Formulation Development

Formulation Development

Right from project kick-off an experienced formulation scientist will be an integral part of the rapidd™ project team. The Formulation Scientist will be responsible for developing your preclinical formulation. Their early involvement also ensures that they are aware of all the information generated during chemical development and solid state characterisation of your API.  Using all available pre-formulation information we ensure a quality by design approach right from the start of drug product development.

If your API has appropriate properties and you want to minimise time and expenditure we can fill API into capsule shells or API in bottles for reconstitution at the clinic.  Alternatively if bioavailability enhancement needs to be investigated using techniques such as amorphous dispersions, we can produce a range of formulations and arrange for comparative bioavailability studies to be conducted.

Furthermore, we are open minded about collaborating with a range of established partners if there is a particular niche technology that you would like to investigate.
rapidd™ also offers a wide variety of formulation technologies and approaches, including:

  • Oral Liquid Formulations
    • API in Bottle
    • Co-Solvent Screening, Instruction for Reconstitution & in-use Stability
    • Oral Liquid Formulations
  • Development of Capsule & Tablet Formulations
    • Simple API in Capsule Shell
    • Blending Process Investigations using a Range of Technologies
  • Amorphous and Solubility Enhancement Systems
    • Surfactant and Polymer Screening
    • Spray Drying / Spray Granulation
    • Solubilised System
    • Formulation Optimisation (e.g. suitable for capsule filling)
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