Almac

• API Development & Manufacture
  • Medicinal Chemistry Support
    • Synthesis of Scaffolds
    • Cytotoxics
    • Diazo Chemistry
    • Organophosphorus Chemistry
  • Intermediate and API Supplies
  • Regulatory Support and Quality Systems
• Peptide & Protein Technology
  • Custom Peptides
  • GMP Peptide API
  • Immunograde Peptides
  • Chemokines
    • Native Human Chemokines
    • Biotinylated Chemokines
    • AlexaFluor^® Chemokines
  • Modified Histones
  • Protein Conjugation Technology
    • Almac’s proprietary ligation technology
    • Site-Specific protein ligation applications
    • Technology compatible with prokaryotic and eukaryotic expression
    • PEGylation of antibody fragments: anti-EGFR single domain antibody
    • PEGylation of protein therapeutics : INFa2b & INFb1b
  • Facilities and Equipment
  • Contact Us – Peptide Quote
• rapidd™
  • Benefits
  • Services
  • API
    • API Toxicology & GMP Supply
    • API Radiolabelling
    • Solid State Characterisation
  • Analytical
    • Method Development and Validation
    • API & Drug Product Supply
  • Drug Product
    • Formulation Development
    • Product Manufacture, Packaging, Labelling and Release
  • Pre-Clinical Safety Assessment
  • Regulatory
• Analytical
• Solid State Services
  • Preformulation
    • formufast™
  • Amorphous Materials
  • Cocrystal Screening
  • Counterfeit Analysis
  • Crystallisation Development
  • Polymorph Screening
  • Salt Screening and Selection
  • Solid State Characterisation
  • Scientific Litigation and Prosecution Support
  • Troubleshooting
• Isotope Chemistry
  • Chemistry
  • Analysis
  • cGMP
  • Labels
• Biocatalysis / selectAZyme™
  • selectAZyme™ Applications
  • selectAZyme™ Expertise
  • selectAZyme™ Enzyme Panels
  • Process Development
  • Chiral Building Blocks
  • selectAZyme™ Screening
  • Fermentation and Molecular Biology
  • Metabolite Services
  • Purification
  • Enzyme Panel Quotation Request
• FLEXYTE™ Fluorescence Lifetime Assays
  • Epigenetics
    • HMTs
    • Deiminases
    • Demethylase
    • Epireader Histone Interactions
  • DUB Assays
  • Kinases
    • Ser / thr
    • Tyrosine Kinase
  • Proteases
  • Phosphatases
  • Protein-Ligand Interactions
  • Compound Interference
  • Custom Assay Development
  • Bulk Substrate Provision
• Animal Free Chemokines
  • Chemokine FAQs
  • Chemokine Products
    • Native Human Chemokines
    • Site-specific Biotin Labelled Chemokines
    • Site-specific AF647® Labelled Chemokines
  • Chemokines by Receptor Binding Affinity
    • CCR 1 – 10
    • CXCR 1 – 6
    • Other Receptors
  • Product Information

Troubleshooting

• API issues
  • Crystallinity, Solubility, Stability, Purification, Yield, Screening and Selection
  • Batch to Batch Variation
  • Scale-Up Problems
• Drug Product Issue
  • Dissolution
  • Stability

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