- Biomarker Services
- Companion Diagnostic Development
- Biomarker Clinical Trial Management
- Internal Biomarker Discovery
- Proprietary Discovery Arrays
- Genomic Services
- Bioinformatics Consultancy
- FFPE Solutions
Keyword
Solutions
At Almac we will partner with you from study design right through to delivery and will help you plan your study and guide you with our expertise and knowledge.
We offer a wide range of customisable bioinformatics and biostatistics solutions to fulfil your study requirements, they include:
Biomarker Discovery and Development
- We offer all steps from study design and generation of good quality data to objective evaluation and selection of the most reliable biomarkers. This includes design and execution of platform migration, assay development, validation and regulation.
Exploratory Analysis
- We have capability to discover and understand hidden trends in your data and the relationship to the underlying biological, clinical or technical influences.
Mechanistic and Functional Analysis
- Through the use of proprietary and public databases we can identify and characterise complex biological information in your data. This is achieved through a combination of functional enrichment analysis and investigation of pathways and gene networks.
Traditional and Next Generation Sequencing Data Analysis
- This includes raw sequence processing, homology searches, identification of important sequence features and microarray probe set annotation.
Biostatistics
- Our solutions focus on the design of all aspects of biomarker discovery and validation studies. We offer full biostatistical support for clinical trials involving biomarkers and preparation of relevant regulatory submissions. We also offer association and linkage analysis of genetic data.
Data Integration
- We will support both biomarker discovery and mechanistic functional analysis by combining multiple data sets and data types at both statistical and functional levels.
All our solutions can be delivered with a variety of data types e.g. data-types independent analysis capabilities (array, qPCR, proteomics, metabolomics, IHC, siRNA, clinical data etc).
For further information please click on the downloadable menu.
Downloads
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A key resource for deciphering the molecular basis of cancer subtypes
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Investigation of molecular subtypes within FFPE breast cancer tumors using the Breast Cancer DSA poster AACR 2011
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Bioinformatics Biomarker Discovery Solutions Menu
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Almac Sequence Analysis Menu
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Almac Gene Expression Data Analysis Menu
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Almac Functional Analysis Menu