{"id":1119,"date":"2021-03-30T14:31:47","date_gmt":"2021-03-30T13:31:47","guid":{"rendered":"https:\/\/www.almacgroup.com\/analytical-solid-state\/?page_id=1119"},"modified":"2025-10-01T09:01:59","modified_gmt":"2025-10-01T08:01:59","slug":"pharmaceutical-drug-product-release-testing","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/analytical-solid-state\/pharmaceutical-drug-product-release-testing\/","title":{"rendered":"Pharmaceutical Drug Product Release Testing"},"content":{"rendered":"\n<h3 class=\"wp-block-heading\" id=\"h-almac-s-extensive-expertise-in-performing-release-testing-includes-api-drug-product-medical-devices-and-biologics-we-have-provision-in-place-to-handle-highly-potent-and-controlled-substances\">Almac\u2019s extensive expertise in performing release testing includes API, drug product, medical devices and biologics. We have provision in place to handle highly potent and controlled substances.<\/h3>\n\n\n\n<p>Release testing covers a variety of tests to address the purity, concentration, consistency, identity and safety of the product. Typical testing would comprise of appearance, assay and impurities, dissolution and microbial testing. It is essential that the methodology involved is robust, to ensure the products\u2019 safety and integrity, and reproducible, in order to minimise out-of-specification or out-of-trend repeats .<\/p>\n\n\n\n<p>As well as release testing, we perform method development and validation, and often transfer methods from client and third party sites. We also have an extensive library of in-house methods, and significant experience working with pharmacopeial methods. We routinely work on NCEs and set specifications in line with ICH guidelines.<\/p>\n\n\n\n<div style=\"height:11px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<!-- Accordions -->\n<section class=\"u-bg-white u-p-y4 t-theme-component-overwrite\" id=\"accordionBlock\">\n\t<div class=\"o-wrapper\">\n\t\t<div class=\"o-grid o-grid--center\">\n\t\t\t<div class=\"o-grid__item u-width-full u-align-center u-align-left@m\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-c-dark-grey u-a-center@s\"><p style=\"text-align: left;\"><strong>Typical release testing methods include:<\/strong><\/p>\n<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t<div class=\"u-m-t2\">\n\t\t\t\t\t<div class=\"c-accordion js-accordion\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item1\" class=\"c-accordion__item u-c-dark-grey accordion-1\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">U(H)PLC<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>U(H)PLC \u2013 Ultra (High) Performance Liquid Chromatography testing is the most widely used analytical technique in the pharma industry. U(H)PLC is flexible, reliable and applicable across multiple product types and dosage strengths.<\/p>\n<p>This technique helps determine the assay value (purity) of compounds, and the nature and level of any impurities present. These methods can also be used to monitor the degradation of products to support stability data. U(H)PLC is a powerful technique and can be used in tandem with MS and MS\/MS detectors to provide full characterisation of a range of drugs.<\/p>\n<p>Almac has significant capacity for U(H)PLC testing with a mix of UPLC and HPLC instruments from both Agilent and Waters with a range of detectors including:<\/p>\n<ul>\n<li>Ultraviolet Visible (UV)<\/li>\n<li>Refractive Index (RI)<\/li>\n<li>Fluorescence Intensity (Fl)<\/li>\n<li>Evaporative Light Scattering Detector (ELSD)<\/li>\n<li>Charged Aerosol Detector (CAD)<\/li>\n<li>Mass Spectrometry \u2013 Triple Quad (MS-TQ)<\/li>\n<li>Mass Spectrometry \u2013 Quadrupole Time of Flight (MS-QTOF)<\/li>\n<\/ul>\n<p>We have expertise in developing complex methods for <a href=\"\/api-chemical-development\/\">small molecule API<\/a>, drug product, <a href=\"\/api-chemical-development\/peptide-protein-technology\/\">peptides<\/a> and peptide cocktails, and <a href=\"\/analytical-solid-state\/biologics-testing\/\">biologics<\/a>.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item2\" class=\"c-accordion__item u-c-dark-grey accordion-2\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">ID by NMR testing<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Nuclear magnetic resonance (NMR) testing is a powerful tool in pharmaceutical drug development. By producing molecular structure information, impurities and other substances can be identified and confirmed. This technique is also widely used in biologic development. NMR is a quick and simple technique used primarily to confirm or elucidate the identity of organic compounds. It is also useful to determine potency values where no suitable reference standard is available.<\/p>\n<p>Almac have two GMP NMR instruments (400MHz and 500MHz) allowing full structural elucidation of small molecules and peptides. We have recently invested in a state-of-the-art broadband cryoprobe which offers enhanced sensitivity over ambient temperature probes and allows us to observe 1H &amp; 19F, as well as NMR active nuclei in the resonance frequency range of 15N-31P. We also have a range of 2D NMR capabilities and a highly trained technical team to support interpretation of data.<\/p>\n<p>As well as ID by NMR, we support qNMR for assaying compounds and have experience developing and validating these methods.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item3\" class=\"c-accordion__item u-c-dark-grey accordion-3\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">Residual solvent analysis<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Residual solvent analysis is undertaken to identify traces of solvents remaining from the manufacturing process. This technique is critical to ensure product purity and safety.<\/p>\n<p>Residual solvents must be detected to low ppm levels to ensure the safety of products. The level of scrutiny required will depend on the manufacturing process and the class of solvents that are used. Our team supports our in-house manufacture of NCEs so has extensive experience in setting specifications for class 1, 2 and 3 solvents in line with ICH guidelines. Our Laboratory has the flexibility to use direct injection GC or headspace GC testing as required.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item4\" class=\"c-accordion__item u-c-dark-grey accordion-4\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">Dissolution testing <\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Drug product dissolution testing is a regulatory requirement and is routinely performed for quality control and development purposes to ensure batch-to-batch consistency, for product release and stability testing.<\/p>\n<p>Almac supports dissolution testing for a range of different drug product formulations including tablets, capsules and softgels utilising USP apparatus 1 (basket) and 2 (paddle). We routinely perform comparative dissolution testing for over-encapsulated products. We can also support disintegration testing if required.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item5\" class=\"c-accordion__item u-c-dark-grey accordion-5\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">Moisture content analysis<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Moisture content analysis is an essential testing element throughout the drug development lifecycle for quality control purposes. The level of moisture content can significantly influence the physical properties and quality of nearly all substances and materials at all stages of development and within the final product. High moisture content can also lead to faster degradation of drugs and as such needs to be carefully monitored and controlled.<\/p>\n<p>Almac perform water determination by Karl Fisher testing:<\/p>\n<ul>\n<li>Volumetric<\/li>\n<li>Coulometric<\/li>\n<li>Stromboli Oven<\/li>\n<\/ul>\n<p><a href=\"\/analytical-solid-state\/solid-state-services\/\">Our physical sciences group<\/a> can also investigate hygroscopicity of samples and formation of different hydrates. Their crystallisation team can look deep into the crystal structure for embedded water, and develop new methods of crystallisation to ensure robust and reproducible crystal formation.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item6\" class=\"c-accordion__item u-c-dark-grey accordion-6\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">Method transfer <\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Analytical Method Transfers are performed between two or more testing laboratories \u2013 it\u2019s a documented process that qualifies a new laboratory to use an analytical method developed by another laboratory. This could be between laboratories at different companies organisations or between two laboratories within the same company organisation.<\/p>\n<p>A formal Analytical method transfer will streamline the testing process, ensuring the method performs well efficiently in the new laboratory, and minimising deviations in results. It is important to have validated analytical methods available at more than one testing site to secure continuity of supply.<\/p>\n<p>Almac can also act as a contingency laboratory to safeguard the continuity of commercial products.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item7\" class=\"c-accordion__item u-c-dark-grey accordion-7\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">Microbiology<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Microbiology: Pharmaceuticals, biopharmaceuticals, biologics and medical devices need to be produced in accordance to the strictest cGMP requirements and must have release testing packages carefully designed to demonstrate compliance. Microbiology testing provides knowledge and understanding any microorganisms and toxins in raw materials, intermediates, finished products, etc. The objective of microbiology testing is to ensure the safe manufacture of pharmaceutical and healthcare preparations and medical devices which involves risk assessment analysis and environmental monitoring.<\/p>\n<p><a href=\"\/analytical-solid-state\/microbiology-testing-overview\/\">Find out more.\u00a0<\/a><\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item8\" class=\"c-accordion__item u-c-dark-grey accordion-8\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">Clinical trial supply support <\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Clinical supply: Before a drug can be used in a clinical trial, extensive analytical testing must be performed to ensure its safety and effectiveness, often in comparison to a standard treatment already offered. Almac is unmatched in its ability to manufacture clinical trial supplies and provide analytical support, with fully integrated sites in the UK, EU and US.<\/p>\n<p><a href=\"https:\/\/www.almacgroup.com\/clinical-services\/analytical-services-for-clinical-trial-supply\/\">Find out more.\u00a0<\/a><\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item9\" class=\"c-accordion__item u-c-dark-grey accordion-9\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">Pharmacopoeial \/ Raw material analysis <\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Raw material testing is an essential activity to ensure that every ingredient used to formulate a drug fully meets the required specifications and requirements.<\/p>\n<p>We perform GMP testing of raw materials, APIs, excipients and drug products for compliance with appropriate standards, according to pharmacopoeial monographs and client methods.<\/p>\n<p>Our scientists have over 10 years\u2019 experience and detailed knowledge of methods in a range of pharmacopoeias, including EP, USP, BP and JP which enables us to provide dedicated support for pharmacopoeial testing.<\/p>\n<p>A full suite of\u00a0<a href=\"https:\/\/www.almacgroup.com\/wp-content\/uploads\/2018\/09\/Almac-AS-Equipment-List.pdf\" target=\"_blank\" rel=\"noopener\">analytical equipment<\/a>\u00a0allows us to offer chemical and physical analysis covering all pharmacopoeial monographs.<\/p>\n<p>In addition to monograph testing, Almac has the ability to develop and validate new methods or transfer existing methods from our clients. We can work with your QC department to provide reliable test results quickly.<\/p>\n<p>Impurities such as N-Nitrosodimethylamine (NDMA) have been highlighted by the US FDA, EMA and other regulatory authorities as an area for concern as they are probable human carcinogens. We have responded to regulatory guidance and offer laboratory drug testing to detect levels of NDMA and related impurities within our mass spectrometry laboratory. Our expert team have successfully performed testing on a number of APIs and Finished Products as per FDA method FY20-006-DPA-S_LCMSMS 10\/17\/2019 to establish levels of NDMA. Read our<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/conducting-nitrosamine-impurity-testing-and-analysis-on-drug-substance-and-drug-product\/\">\u00a0paper<\/a> to find out more.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item10\" class=\"c-accordion__item u-c-dark-grey accordion-10\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-dark-grey js-accordionTarget-one\">Reference standard management<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Reference standards are a vital element within pharmaceutical drug development at every stage of analytical support. Typical reference standard management includes techniques such as characterisation, expiry dating, re-certification, and storage and distribution. A comprehensive reference standard management program is critical to ensure there are no avoidable delays within the drug development process.<\/p>\n<p>Almac manage a catalogue of &gt;2000 reference standards over a range of storage conditions across our <a href=\"\/analytical-solid-state\/almac-sciences-analytical-laboratories\/\">UK, European<\/a> and <a href=\"\/analytical-solid-state\/global-analytical-services-in-the-us\/\">American analytical labs<\/a>.<\/p>\n<p>Our highly organised and proficient team enable prompt recertification. We also manage resupply of standards when stocks run low via our synthetic chemistry group, who can manufacture standards and by\/degradation products of API and drug product. This can be done via total synthesis or isolation from manufacturer supplied mother liquors or enriched waste streams. We have significant knowledge on best practice in this area and have been managing the standard portfolio of a big pharma partner for &gt;15 years.<\/p>\n<p><!--<iframe data-src=\"https:\/\/player.vimeo.com\/video\/668647071?h=54c6c0f61c\" width=\"500\" height=\"500\" frameborder=\"0\" allowfullscreen=\"allowfullscreen\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" class=\"lazyload\" data-load-mode=\"1\">--><\/iframe><\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- AL-549 - Sciences Ref Standard (Jigsaw) Graphic (Jigsaw Accordion) -->\r\n<div class=\"u-p-y5 u-p-y3@m js-jigsaw-accordion\">\r\n    <div class=\"o-wrapper\">\r\n        <div class=\"o-grid\">\r\n            <div class=\"o-grid__item u-width-half u-width-full@m u-m-b3@m\">\r\n\r\n                <h4 class=\"u-color-grey u-m-b4 u-align-center@m c-jigsaw__title\">Full reference standard management<\/h4>                   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fill=\"white\"\/>\r\n                    <path d=\"M88.8418 13.6828H87.8431V11.3786H88.8418V13.6828ZM89.4553 10.7651H87.2225V14.3319H89.4553V10.7651Z\" fill=\"white\"\/>\r\n                    <path d=\"M92.0947 11.0708H90.4825V13.9884H92.0947V11.0708Z\" fill=\"white\"\/>\r\n                    <path d=\"M91.7808 13.6828H90.7892V11.3786H91.7808V13.6828ZM92.4014 10.7651H90.1686V14.3319H92.4014V10.7651Z\" fill=\"white\"\/>\r\n                    <path d=\"M94.8554 11.0708H93.2432V13.9884H94.8554V11.0708Z\" fill=\"white\"\/>\r\n                    <path d=\"M94.5557 13.6828H93.557V11.3786H94.5557V13.6828ZM95.1692 10.7651H92.9435V14.3319H95.1692V10.7651Z\" fill=\"white\"\/>\r\n                    <path d=\"M97.6803 11.0708H96.0681V13.9884H97.6803V11.0708Z\" fill=\"white\"\/>\r\n                    <path d=\"M97.3806 13.6828H96.3819V11.3786H97.3806V13.6828ZM97.9941 10.7651H95.7684V14.3319H97.9941V10.7651Z\" fill=\"white\"\/>\r\n                    <path d=\"M96.6886 17.5271L96.2178 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          <path d=\"M20.9088 21.9483C20.7703 21.9471 20.6347 21.987 20.519 22.0631C20.4033 22.1391 20.3127 22.2478 20.2589 22.3754C20.2051 22.5029 20.1904 22.6436 20.2167 22.7796C20.2429 22.9155 20.309 23.0406 20.4065 23.1389C20.504 23.2372 20.6285 23.3044 20.7642 23.3319C20.8999 23.3593 21.0407 23.3458 21.1687 23.2931C21.2967 23.2404 21.4062 23.1509 21.4833 23.0358C21.5603 22.9208 21.6015 22.7855 21.6015 22.647C21.6023 22.5555 21.5849 22.4648 21.5505 22.3801C21.516 22.2953 21.4652 22.2183 21.4008 22.1533C21.3364 22.0883 21.2597 22.0368 21.1753 22.0016C21.0909 21.9664 21.0003 21.9483 20.9088 21.9483Z\" fill=\"white\"\/>\r\n                            <\/svg>\r\n\r\n                            <h4 class=\"u-color-white u-m-b0 u-m-l3\">Qualification<\/h4>\r\n\r\n                        <\/div>\r\n\r\n                        <div class=\"c-jigsaw-accordion__content\">\r\n\r\n                            <div class=\"s-cms u-text-small u-color-black\">\r\n                               <p>Each reference standard must be qualified prior to use. This comprises  a range of analysis to demonstrate compound characterization and purity including batch aliquoting, purification and isolation for by degradation products. Upon isolation, characterisation (typically by orthogonal methods, both chromatographic and spectroscopic) is necessary to confirm structure and purity. As part of qualification, a specification is issued for each standard which includes details on shelf-life and retest date.<\/p>\r\n                            <\/div>\r\n\r\n                        <\/div>\r\n\r\n                    <\/div>\r\n                    <!-- \/ Qualification -->\r\n\r\n\r\n                    <!-- Storage -->\r\n                    <div class=\"c-jigsaw-accordion__item c-jigsaw-accordion__item--green\" data-id=\"Storage\">\r\n                    \r\n                        <div class=\"c-jigsaw-accordion__title\">\r\n\r\n                            <svg width=\"33\" height=\"33\" viewBox=\"0 0 33 33\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\r\n                                <path d=\"M8.20123 12.8418L9.6595 13.7228\" stroke=\"#00C784\" stroke-width=\"3.64\" stroke-miterlimit=\"10\"\/>\r\n                                <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" d=\"M22.6257 2.26364C25.442 3.47524 27.8358 5.4948 29.5042 8.0669C31.1725 10.639 32.0406 13.6481 31.9985 16.7135C31.9565 19.779 31.0062 22.7631 29.2679 25.2885C27.5296 27.8139 25.0814 29.767 22.2328 30.9009C19.3843 32.0348 16.2635 32.2985 13.2651 31.6587C10.2666 31.0188 7.52532 29.5042 5.38786 27.3063C3.25039 25.1085 1.81283 22.3261 1.25693 19.3112C0.701027 16.2962 1.05176 13.1842 2.26483 10.3686C3.0693 8.49938 4.23416 6.80696 5.69285 5.38799C7.15153 3.96901 8.87547 2.85128 10.7662 2.09864C12.657 1.34599 14.6775 0.973189 16.7124 1.0015C18.7472 1.02981 20.7566 1.45868 22.6257 2.26364V2.26364Z\" fill=\"#00C784\" stroke=\"white\" stroke-width=\"2\" stroke-miterlimit=\"10\"\/>\r\n                                <path d=\"M17.5888 13.5889H15.8449V15.3265H17.5888V13.5889Z\" fill=\"white\"\/>\r\n                                <path d=\"M15.2068 13.5889H13.463V15.3265H15.2068V13.5889Z\" fill=\"white\"\/>\r\n                                <path d=\"M12.7825 13.5889H11.0387V15.3265H12.7825V13.5889Z\" fill=\"white\"\/>\r\n                                <path d=\"M22.4618 13.5889H20.718V15.3265H22.4618V13.5889Z\" fill=\"white\"\/>\r\n                                <path d=\"M20.0374 13.5889H18.2936V15.3265H20.0374V13.5889Z\" fill=\"white\"\/>\r\n                                <path d=\"M15.6747 11.6201H9.18546V21.3412H24.2055V11.6201H16.5861H15.6747ZM23.2697 12.5254V20.4238H18.7492V17.4831H14.6235V20.4238H10.0665V12.5254H23.2697Z\" fill=\"white\"\/>\r\n                            <\/svg>\r\n\r\n                            <h4 class=\"u-color-white u-m-b0 u-m-l3\">Storage<\/h4>\r\n\r\n                        <\/div>\r\n\r\n                        <div class=\"c-jigsaw-accordion__content\">\r\n\r\n                            <div class=\"s-cms u-text-small u-color-black\">\r\n                                <p>Reference standards are typically stored under controlled conditions to prevent degradation. Depending on the nature of the compound this could be controlled ambient, chilled, or frozen. As well as temperature, the storage conditions may have limitations around oxygen, air or water exposure, and each standard will come with specific storage instructions.<\/p>\r\n                            <\/div>\r\n\r\n                        <\/div>\r\n\r\n                    <\/div>\r\n                    <!-- \/ Storage -->\r\n\r\n\r\n                    <!-- Aliquoting -->\r\n                    <div class=\"c-jigsaw-accordion__item c-jigsaw-accordion__item--orange\" data-id=\"Aliquoting\">\r\n                    \r\n                        <div class=\"c-jigsaw-accordion__title\">\r\n\r\n                            <svg width=\"33\" height=\"33\" viewBox=\"0 0 33 33\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\r\n                                <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" d=\"M22.6235 2.26269C25.4399 3.4738 27.8339 5.49286 29.5026 8.06454C31.1714 10.6362 32.04 13.645 31.9986 16.7103C31.9572 19.7757 31.0076 22.7599 29.2699 25.2856C27.5323 27.8112 25.0846 29.7649 22.2365 30.8994C19.3884 32.034 16.2678 32.2986 13.2693 31.6596C10.2709 31.0206 7.52926 29.5069 5.39122 27.3098C3.25317 25.1126 1.81475 22.3309 1.25786 19.3163C0.700977 16.3016 1.05065 13.1896 2.26265 10.3737C3.06654 8.50396 4.23098 6.81095 5.68942 5.39134C7.14786 3.97173 8.87172 2.85334 10.7625 2.10011C12.6533 1.34688 14.674 0.973561 16.7092 1.00146C18.7443 1.02935 20.754 1.45791 22.6235 2.26269Z\" fill=\"#FF8539\" stroke=\"white\" stroke-width=\"2\" stroke-miterlimit=\"10\"\/>\r\n                                <path d=\"M18.99 8.69726C18.99 8.91957 18.924 9.13686 18.8005 9.3217C18.677 9.50655 18.5015 9.65063 18.2961 9.7357C18.0907 9.82077 17.8647 9.84304 17.6466 9.79967C17.4286 9.7563 17.2283 9.64922 17.0711 9.49203C16.9139 9.33483 16.8068 9.13457 16.7634 8.91654C16.72 8.6985 16.7423 8.47249 16.8274 8.2671C16.9125 8.06172 17.0565 7.88617 17.2414 7.76266C17.4262 7.63916 17.6436 7.57324 17.8659 7.57324C18.0135 7.57324 18.1597 7.60231 18.2961 7.65879C18.4324 7.71528 18.5564 7.79809 18.6607 7.90246C18.7651 8.00684 18.8479 8.13073 18.9044 8.2671C18.9609 8.40347 18.99 8.54966 18.99 8.69726Z\" fill=\"white\"\/>\r\n                                <path d=\"M16.2984 6.44909C16.2936 6.6703 16.2236 6.88517 16.0972 7.06678C15.9708 7.2484 15.7936 7.38867 15.5879 7.47003C15.3821 7.55138 15.1569 7.5702 14.9405 7.52413C14.724 7.47805 14.526 7.36916 14.3713 7.21104C14.2165 7.05292 14.1118 6.85263 14.0704 6.63529C14.0289 6.41794 14.0526 6.1932 14.1383 5.98923C14.2241 5.78525 14.3681 5.61111 14.5524 5.48864C14.7367 5.36618 14.953 5.30083 15.1743 5.30078C15.4724 5.30078 15.7583 5.41921 15.9691 5.63C16.1799 5.8408 16.2984 6.12666 16.2984 6.42477\" fill=\"white\"\/>\r\n                                <path d=\"M19.4275 14.062H20.0898V10.9756H13.5702V14.062H14.2629L12.7074 15.7024V24.8949H21.0012V15.6964L19.4275 14.062ZM14.5667 11.9416H19.1602V13.096H14.5667V11.9416ZM20.0351 20.8971H16.7784V18.0598H20.0351V20.8971ZM15.8122 17.1059V21.8632H20.0351V23.9289H13.6796V16.0852L15.5996 14.062H18.0908L20.0351 16.0913V17.1059H15.8122Z\" fill=\"white\"\/>\r\n                            <\/svg>\r\n\r\n                            <h4 class=\"u-color-white u-m-b0 u-m-l3\">Aliquoting<\/h4>\r\n\r\n                        <\/div>\r\n\r\n                        <div class=\"c-jigsaw-accordion__content\">\r\n\r\n                            <div class=\"s-cms u-text-small u-color-black\">\r\n                                <p>Standards are typically used in small quantities by several different parties. For example, both the API and drug product manufacturers require access and for commercial drugs with large volumes there could be multiple suppliers for each worldwide. Typically, the reference standards are provided in bulk to a supplier where they are aliquoted into smaller vials and shared with sites that require them. This vialling prevents waste as once the standard is expired it can no longer be used.<\/p>\r\n                            <\/div>\r\n\r\n                        <\/div>\r\n\r\n                    <\/div>\r\n                    <!-- \/ Aliquoting -->\r\n\r\n\r\n                    <!-- Shipment -->\r\n                    <div class=\"c-jigsaw-accordion__item c-jigsaw-accordion__item--blue\" data-id=\"Shipment\">\r\n                    \r\n                        <div class=\"c-jigsaw-accordion__title\">\r\n\r\n                            <svg width=\"33\" height=\"33\" viewBox=\"0 0 33 33\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\r\n                                <path d=\"M30.3014 11.1445L28.8431 11.7278\" stroke=\"#74BBE7\" stroke-width=\"3.64\" stroke-miterlimit=\"10\"\/>\r\n                                <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" d=\"M22.6213 2.26175C25.4378 3.47237 27.832 5.49095 29.5011 8.06221C31.1703 10.6335 32.0394 13.6419 31.9986 16.7071C31.9578 19.7724 31.009 22.7566 29.272 25.2826C27.535 27.8085 25.0879 29.7627 22.2403 30.898C19.3926 32.0332 16.2722 32.2986 13.2736 31.6605C10.2751 31.0224 7.53318 29.5095 5.39455 27.3132C3.25593 25.1168 1.81667 22.3357 1.2588 19.3214C0.700935 16.3071 1.04951 13.195 2.26044 10.3788C3.06377 8.50857 4.22779 6.81492 5.68598 5.39467C7.14417 3.97442 8.86796 2.85541 10.7588 2.10159C12.6497 1.34777 14.6706 0.973934 16.706 1.00141C18.7414 1.02889 20.7515 1.45716 22.6213 2.26175V2.26175Z\" fill=\"#74BBE7\" stroke=\"white\" stroke-width=\"2\" stroke-miterlimit=\"10\"\/>\r\n                                <path d=\"M13.3615 11.1931L8.7619 10.6523L8.20898 11.4179L11.6298 13.0097L13.3615 11.1931Z\" fill=\"white\"\/>\r\n                                <path d=\"M23.6421 19.1516C23.6412 19.0813 23.6178 19.0132 23.5752 18.9572C23.2593 18.5137 22.9373 18.0762 22.6213 17.6449L21.8193 16.5209C21.802 16.4933 21.7777 16.471 21.7488 16.456C21.72 16.441 21.6877 16.4341 21.6552 16.4358H19.8324V21.2417H20.6041C20.6134 21.5249 20.7318 21.7935 20.9344 21.9916C21.137 22.1897 21.4083 22.3019 21.6917 22.3049V22.3049C21.9768 22.3021 22.2502 22.1905 22.4557 21.9929C22.6613 21.7952 22.7836 21.5265 22.7975 21.2417H23.6421V20.707C23.6421 20.2088 23.6421 19.6924 23.6421 19.182V19.1516ZM22.1778 21.6609C22.1199 21.7216 22.05 21.7697 21.9727 21.8021C21.8953 21.8345 21.812 21.8506 21.7281 21.8492C21.6438 21.8492 21.5604 21.8325 21.4826 21.8001C21.4048 21.7677 21.3342 21.7201 21.2748 21.6602C21.2155 21.6004 21.1687 21.5293 21.137 21.4512C21.1053 21.3731 21.0893 21.2895 21.0901 21.2052C21.0876 21.0475 21.1464 20.895 21.2542 20.7799C21.3139 20.7132 21.3869 20.6598 21.4685 20.6232C21.5502 20.5865 21.6386 20.5675 21.7281 20.5673V20.5673C21.812 20.5659 21.8953 20.582 21.9727 20.6144C22.05 20.6468 22.1199 20.6949 22.1778 20.7556C22.2946 20.8785 22.3599 21.0416 22.36 21.2113C22.3614 21.2952 22.3453 21.3784 22.3129 21.4558C22.2805 21.5332 22.2324 21.603 22.1717 21.6609H22.1778ZM20.3792 18.8357V17.013H21.4061C21.4195 17.0153 21.4323 17.0203 21.4438 17.0276C21.4552 17.0349 21.4651 17.0444 21.4729 17.0555L22.6395 18.7081L22.7307 18.8357H20.3792Z\" fill=\"white\"\/>\r\n                                <path d=\"M13.3129 20.1605V21.1873H14.3883C14.3925 21.4527 14.4969 21.7067 14.6806 21.8982C14.8643 22.0898 15.1137 22.2048 15.3787 22.2201C15.6261 22.2377 15.8712 22.1618 16.0653 22.0075C16.19 21.908 16.2915 21.7825 16.3629 21.6398C16.4342 21.4971 16.4737 21.3406 16.4785 21.1812V21.1508H19.1762V20.124H13.3129V20.1605ZM15.4334 20.4825C15.5249 20.4825 15.6155 20.5006 15.6999 20.5358C15.7843 20.571 15.861 20.6225 15.9254 20.6875C15.9898 20.7525 16.0407 20.8295 16.0751 20.9143C16.1096 20.999 16.1269 21.0897 16.1261 21.1812C16.1248 21.3649 16.053 21.541 15.9256 21.6733C15.8613 21.7386 15.7847 21.7905 15.7002 21.8259C15.6157 21.8614 15.525 21.8797 15.4334 21.8799C15.2481 21.8799 15.0704 21.8063 14.9393 21.6752C14.8083 21.5442 14.7347 21.3665 14.7347 21.1812C14.7347 20.9959 14.8083 20.8182 14.9393 20.6871C15.0704 20.5561 15.2481 20.4825 15.4334 20.4825\" fill=\"white\"\/>\r\n                                <path d=\"M19.1944 15.7131H15.6399L15.2632 12.414L17.1346 10.3969C17.1346 10.3969 18.0703 9.64347 17.5478 9.06628C17.0252 8.48909 16.2171 9.21209 16.2171 9.21209L10.1107 15.3789L8.45193 15.142L8.21497 15.6159L10.0378 16.4118L10.8823 18.3378L11.2712 18.0097L11.1801 16.2903L13.1062 14.4068L13.7867 15.707H13.5923C13.5561 15.7039 13.5196 15.7083 13.4851 15.7198C13.4506 15.7313 13.4189 15.7497 13.3918 15.7738C13.3644 15.7992 13.3431 15.8304 13.3295 15.8651C13.3158 15.8998 13.3101 15.9371 13.3128 15.9743V19.7352H19.3888V15.8953V15.7252L19.1944 15.7131ZM19.006 19.3585H13.7199V18.9393C13.7199 17.9854 13.7199 17.0254 13.7199 16.0594H14.0054L15.1842 18.3256L15.8647 17.6694L15.6824 16.0594H19.0121L19.006 19.3585Z\" fill=\"white\"\/>\r\n                            <\/svg>\r\n\r\n                            <h4 class=\"u-color-white u-m-b0 u-m-l3\">Shipment<\/h4>\r\n\r\n                        <\/div>\r\n\r\n                        <div class=\"c-jigsaw-accordion__content\">\r\n\r\n                            <div class=\"s-cms u-text-small u-color-black\">\r\n                                <p>Once the standards have been portioned out, they need to be sent to the appropriate facility. This shipping exercise includes preparation of GMP paperwork (including certificates of analysis and custom forms) to ensure that the vials are received in a timely fashion. The location of these standards is especially important if vendors are spread over different continents. <\/p>\r\n                            <\/div>\r\n\r\n                        <\/div>\r\n\r\n                    <\/div>\r\n                    <!-- \/ Shipment -->\r\n\r\n\r\n                    <!-- Recertification -->\r\n                    <div class=\"c-jigsaw-accordion__item c-jigsaw-accordion__item--purple\" data-id=\"Recertification\">\r\n                    \r\n                        <div class=\"c-jigsaw-accordion__title\">\r\n\r\n                            <svg width=\"33\" height=\"33\" viewBox=\"0 0 33 33\" fill=\"none\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\">\r\n                                <path fill-rule=\"evenodd\" clip-rule=\"evenodd\" d=\"M22.6235 2.26269C25.4399 3.4738 27.8339 5.49288 29.5026 8.06456C31.1714 10.6362 32.04 13.645 31.9986 16.7103C31.9572 19.7757 31.0076 22.7599 29.2699 25.2855C27.5323 27.8112 25.0846 29.7649 22.2365 30.8994C19.3884 32.034 16.2678 32.2986 13.2694 31.6596C10.2709 31.0206 7.52926 29.5069 5.39121 27.3098C3.25317 25.1126 1.81474 22.3309 1.25786 19.3163C0.700974 16.3016 1.05065 13.1896 2.26266 10.3737C3.06655 8.50398 4.23098 6.81094 5.68942 5.39133C7.14785 3.97172 8.87172 2.85335 10.7625 2.10012C12.6533 1.34689 14.674 0.973561 16.7092 1.00146C18.7443 1.02935 20.754 1.45792 22.6235 2.26269Z\" fill=\"#9059B5\" stroke=\"white\" stroke-width=\"1.91\" stroke-miterlimit=\"10\"\/>\r\n                                <path d=\"M23.62 26.584L24.5314 27.8538\" stroke=\"#9059B5\" stroke-width=\"3.64\" stroke-miterlimit=\"10\"\/>\r\n                                <path d=\"M9.96716 23.0717H22.2955V10.7441H9.96716V23.0717ZM11.0305 13.138H21.2564V22.0145H11.0305V13.138Z\" fill=\"white\"\/>\r\n                                <path d=\"M13.0355 9.57812H11.6624V12.0631H13.0355V9.57812Z\" fill=\"white\"\/>\r\n                                <path d=\"M12.7804 11.8014H11.9297V9.83891H12.7804V11.8014ZM13.3029 9.31641H11.4011V12.3542H13.3029V9.31641Z\" fill=\"white\"\/>\r\n                                <path d=\"M15.5509 9.57812H14.1777V12.0631H15.5509V9.57812Z\" fill=\"white\"\/>\r\n                                <path d=\"M15.2837 11.8014H14.4391V9.83891H15.2837V11.8014ZM15.8123 9.31641H13.9105V12.3542H15.8123V9.31641Z\" fill=\"white\"\/>\r\n                                <path d=\"M17.9024 9.57812H16.5292V12.0631H17.9024V9.57812Z\" fill=\"white\"\/>\r\n                                <path d=\"M17.6472 11.8014H16.7966V9.83891H17.6472V11.8014ZM18.1698 9.31641H16.274V12.3542H18.1698V9.31641Z\" fill=\"white\"\/>\r\n                                <path d=\"M20.3086 9.57812H18.9354V12.0631H20.3086V9.57812Z\" fill=\"white\"\/>\r\n                                <path d=\"M20.0534 11.8014H19.2027V9.83891H20.0534V11.8014ZM20.5759 9.31641H18.6802V12.3542H20.5759V9.31641Z\" fill=\"white\"\/>\r\n                                <path d=\"M19.4639 15.0761L19.0629 14.6934L15.8122 18.0654L14.0684 16.4978L13.6978 16.9171L15.8426 18.8309L19.4639 15.0761Z\" fill=\"white\"\/>\r\n                            <\/svg>\r\n\r\n                            <h4 class=\"u-color-white u-m-b0 u-m-l3\">Recertification<\/h4>\r\n\r\n                        <\/div>\r\n\r\n                        <div class=\"c-jigsaw-accordion__content\">\r\n\r\n                            <div class=\"s-cms u-text-small u-color-black\">\r\n                                <p>Depending on the nature of the standard, recertification may be required annually, or every 2-3 years. Almac\u2019s lab management system can track expiry dates, inventory and stock levels to ensure standards are always ready and available to use. <\/p>\r\n                                <p>Almac\u2019s labs have the capacity and capability to perform full management of reference standard programs on behalf of our clients. We have more than 20 year\u2019s experience in this area with long standing relationships with a number of key partners. Almac\u2019s flexible approach makes us the partner of choice for reference standard programs.<\/p>\r\n                            <\/div>\r\n\r\n                        <\/div>\r\n\r\n                    <\/div>\r\n                    <!-- \/ Recertification -->\r\n                \r\n                <\/div>\r\n            \r\n            <\/div>\r\n        <\/div>\r\n    <\/div>\r\n<\/div>\r\n<!-- \/ AL-549 - Sciences Ref Standard (Jigsaw) Graphic (Jigsaw Accordion) -->\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/div> <!-- \/c-tabs -->\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div> <!-- \/o-grid -->\n\t<\/div> <!-- \/o-wrapper -->\n<\/section>\n\n\n\n<div style=\"height:66px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t<article class=\"o-grid o-grid--full\">\n\n\t\t<div class=\"o-grid__item u-width-full u-m-t6 u-m-t4@m u-m-b4\">\n\t\t\t<h2 class=\"u-normal u-a-center\">Related Resources <\/h2>\n\t\t<\/div>\n\n\t\t<div class=\"u-flex u-flex-justify-center u-flex-wrap u-width-full c-news-panels__slider js-news-panels\">\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/generic-method-approach-for-determination-of-residual-solvents-in-active-pharmaceutical-ingredients-by-gas-chromatography\/\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2023\/11\/SI_Whitepaper_Tile.png&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Whitepaper<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-light-grey\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">Generic method approach for determination of residual solvents in active pharmaceutical ingredients by gas chromatography<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/wp-content\/uploads\/sites\/10\/2025\/10\/Analytical-Method-case-study-for-synthetic-peptide-purity.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2023\/11\/170601_KAP1_118-scaled.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Case Study<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-light-grey\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">Analytical method development for synthetic peptide purity and impurities content by UHPLC \u2013 illustrated case study<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/peptide-uhplc-development-2\/\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2023\/09\/Peptide-UHPLC-development.png&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Almac Voice<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-light-grey\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">Peptide UHPLC development<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/qnmr-a-modern-alternative-to-hplc\/\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2021\/11\/QNMR-a-modern-alternative-to-HPLC.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Almac Voice<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-light-grey\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">QNMR \u2013 a modern alternative to HPLC<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/wp-content\/uploads\/2020\/04\/NMR-under-GxP-in-Drug-Development-and-Manufacturing.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2021\/03\/1.jpeg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Webinar<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-light-grey\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">NMR under GxP in Drug Development Manufacturing<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/conducting-nitrosamine-impurity-testing-and-analysis-on-drug-substance-and-drug-product\/\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2020\/12\/Conducting-Nitrosamine-impurity-testing-and-analysis-on-drug-substance-and-drug-product.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Almac voice<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-light-grey\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">Conducting Nitrosamine impurity testing and analysis on drug substance and drug product<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/quality-control-release-testing-more-than-a-tick-box-exercise\/\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2021\/07\/qual.png&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Almac Voice<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-light-grey\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">Quality Control Release Testing \u2013 more than a tick box exercise<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/wp-content\/uploads\/sites\/10\/2023\/10\/Almac-equipment-List-Analytical-Services.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2021\/03\/3.png&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Equipment List<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-light-grey\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">Analytical equipment list <\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t<\/div>\n\t<\/article>\n\n\n<!-- <article id=\"related\">\n\t<div class=\"o-grid\">\n\t\t\t\t<div class=\"o-grid__item u-width-full u-a-center\">\n\t\t\t\t\t\t\t<h3 class=\"u-normal u-m-b4\">Related Resources <\/h3>\n\t\t\t\t\t<\/div>\n\t\n\t\t<div class=\"u-flex u-flex-justify-center u-flex-wrap u-width-full c-resources__slider js-resources-panels\">\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/generic-method-approach-for-determination-of-residual-solvents-in-active-pharmaceutical-ingredients-by-gas-chromatography\/\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2023\/11\/SI_Whitepaper_Tile.png&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Whitepaper<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">Generic method approach for determination of residual solvents in active pharmaceutical ingredients by gas chromatography<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/wp-content\/uploads\/sites\/10\/2025\/10\/Analytical-Method-case-study-for-synthetic-peptide-purity.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2023\/11\/170601_KAP1_118-scaled.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Case Study<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">Analytical method development for synthetic peptide purity and impurities content by UHPLC \u2013 illustrated case study<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/peptide-uhplc-development-2\/\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2023\/09\/Peptide-UHPLC-development.png&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Almac Voice<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">Peptide UHPLC development<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/qnmr-a-modern-alternative-to-hplc\/\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2021\/11\/QNMR-a-modern-alternative-to-HPLC.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Almac Voice<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">QNMR \u2013 a modern alternative to HPLC<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/wp-content\/uploads\/2020\/04\/NMR-under-GxP-in-Drug-Development-and-Manufacturing.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2021\/03\/1.jpeg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Webinar<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">NMR under GxP in Drug Development Manufacturing<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/conducting-nitrosamine-impurity-testing-and-analysis-on-drug-substance-and-drug-product\/\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2020\/12\/Conducting-Nitrosamine-impurity-testing-and-analysis-on-drug-substance-and-drug-product.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Almac voice<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">Conducting Nitrosamine impurity testing and analysis on drug substance and drug product<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/quality-control-release-testing-more-than-a-tick-box-exercise\/\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2021\/07\/qual.png&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Almac Voice<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">Quality Control Release Testing \u2013 more than a tick box exercise<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/wp-content\/uploads\/sites\/10\/2023\/10\/Almac-equipment-List-Analytical-Services.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2021\/03\/3.png&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Equipment List<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">Analytical equipment list <\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/article> -->\n","protected":false},"excerpt":{"rendered":"<p>Almac\u2019s extensive expertise in performing release testing includes API, drug product, medical devices and biologics. We have provision in place to handle highly potent and controlled substances. Release testing covers a variety of tests to address the purity, concentration, consistency, identity and safety of the product. Typical testing would comprise of appearance, assay and impurities, [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1119","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Pharmaceutical Drug Product Release Testing - Analytical &amp; Solid State Services<\/title>\n<meta name=\"description\" content=\"Almac\u2019s extensive expertise in performing release testing includes API, drug product, medical devices and biologics.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/pharmaceutical-drug-product-release-testing\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Pharmaceutical Drug Product Release Testing\" \/>\n<meta property=\"og:description\" content=\"Almac\u2019s extensive expertise in performing release testing includes API, drug product, medical devices and biologics.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/pharmaceutical-drug-product-release-testing\/\" \/>\n<meta property=\"og:site_name\" content=\"Analytical &amp; 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