{"id":1619,"date":"2024-09-30T16:11:23","date_gmt":"2024-09-30T15:11:23","guid":{"rendered":"https:\/\/www.almacgroup.com\/analytical-solid-state\/?page_id=1619"},"modified":"2025-11-18T12:08:02","modified_gmt":"2025-11-18T12:08:02","slug":"case-studies","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/analytical-solid-state\/case-studies\/","title":{"rendered":"Analytical solid state case studies"},"content":{"rendered":"\n<h4 class=\"wp-block-heading has-medium-font-size\" id=\"h-with-more-than-55-years-experience-our-expert-teams-offer-a-comprehensive-end-to-end-suite-of-analytical-testing-for-a-range-of-product-types-including-small-molecules-peptide-biologics-conjugates-potent-and-controlled-substances-we-have-hundreds-of-success-stories-innovative-solutions-and-best-in-class-service-examples-to-share-in-helping-to-advance-human-health-here-are-just-some-of-them\">With more than 55 years\u2019 experience, our expert teams offer a comprehensive end-to-end suite of analytical testing for a range of product types including small molecules, peptide, biologics, conjugates, potent and controlled substances. We have hundreds of success stories, innovative solutions and best-in-class service examples to share in helping to advance human health. Here are just some of them.<\/h4>\n\n\n<div class=\"o-wrapper\">\n\t<div class=\"o-grid\">\n\n\t\t<div class=\"o-grid__item u-width-full \">\n\t\t\t\t\t<\/div>\n\n\t<\/div>\n            <div class=\"o-grid u-flex-align-stretch u-m-b3\">\n\n            \n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/09\/almacvoice6.jpg\" alt=\"Quantitative NMR of challenging materials\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/09\/almacvoice6.jpg\" alt=\"Quantitative NMR of challenging materials\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Quantitative NMR of challenging materials<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/quantitative-nmr-of-challenging-materials\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/09\/almacvoice11.jpg\" alt=\"N and C terminal sequence analysis\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/09\/almacvoice11.jpg\" alt=\"N and C terminal sequence analysis\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">N and C terminal sequence analysis<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/n-and-c-terminal-sequence-analysis\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/10\/almac_case_study_7.jpg\" alt=\"Spotlight on stability:  API and drug product testing\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/10\/almac_case_study_7.jpg\" alt=\"Spotlight on stability:  API and drug product testing\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Spotlight on stability:  API and drug product testing<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/spotlight-on-stability-api-and-drug-product-testing-2\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/11\/SI_Tile_4.jpg\" alt=\"Determination of Isotopic Purity by Accurate Mass LC\/MS\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/11\/SI_Tile_4.jpg\" alt=\"Determination of Isotopic Purity by Accurate Mass LC\/MS\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Determination of Isotopic Purity by Accurate Mass LC\/MS<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/mass-spectrometry-determination-of-isotopic-purity-by-accurate-mass-lc-ms\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/11\/SI_Tile_5.jpg\" alt=\"Evaluation of the effects of residual carbon content matrix on the determination of pharmaceutically regulated elemental impurities by ICP-MS\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/11\/SI_Tile_5.jpg\" alt=\"Evaluation of the effects of residual carbon content matrix on the determination of pharmaceutically regulated elemental impurities by ICP-MS\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Evaluation of the effects of residual carbon content matrix on the determination of pharmaceutically regulated elemental impurities by ICP-MS<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/evaluation-of-the-effects-of-residual-carbon-content-matrix-on-the-determination-of-pharmaceutically-regulated-elemental-impurities-by-icp-ms\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/12\/SI_case-study_validation_of_GC_tile_square.png\" alt=\"Validation of a GC-FID headspace method for quantitative detection of silicone oils (siloxane polymers) within the lyophilisation life cycle\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 612px; --smush-placeholder-aspect-ratio: 612\/612;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/12\/SI_case-study_validation_of_GC_tile_square.png\" alt=\"Validation of a GC-FID headspace method for quantitative detection of silicone oils (siloxane polymers) within the lyophilisation life cycle\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Validation of a GC-FID headspace method for quantitative detection of silicone oils (siloxane polymers) within the lyophilisation life cycle<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/validation-of-a-gc-fid-headspace-method-for-quantitative-detection-of-silicone-oils\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/10\/almac_case_study_8.jpg\" alt=\"Analytical method development for synthetic peptide purity and impurtities content by UHPLC - illustrated case study\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/10\/almac_case_study_8.jpg\" alt=\"Analytical method development for synthetic peptide purity and impurtities content by UHPLC - illustrated case study\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Analytical method development for synthetic peptide purity and impurtities content by UHPLC &#8211; illustrated case study<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/analytical-method-development-for-synthetic-peptide-for-purity-and-impurities-content-by-uhplc\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/02\/analytical-method-optimisation-case-study-cover_square.jpg\" alt=\"Analytical method optimisation with Fusion QbD software \u2013illustrative case studies for a synthetic peptide and small molecule Active Pharmaceutical Ingredient(API) by Almac Sciences\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/02\/analytical-method-optimisation-case-study-cover_square.jpg\" alt=\"Analytical method optimisation with Fusion QbD software \u2013illustrative case studies for a synthetic peptide and small molecule Active Pharmaceutical Ingredient(API) by Almac Sciences\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Analytical method optimisation with Fusion QbD software \u2013illustrative case studies for a synthetic peptide and small molecule Active Pharmaceutical Ingredient(API) by Almac Sciences<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--red\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/analytical-method-optimisation-with-fusion-qbd-software-illustrative-case-studies-for-a-synthetic-peptide-and-small-molecule-active-pharmaceutical-ingredientapi-by-almac-sciences\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/11\/SI_Tile_7.jpg\" alt=\"Impurity level confirmation by Nuclear Magnetic Resonance (NMR) Spectroscopy\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/11\/SI_Tile_7.jpg\" alt=\"Impurity level confirmation by Nuclear Magnetic Resonance (NMR) Spectroscopy\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Impurity level confirmation by Nuclear Magnetic Resonance (NMR) Spectroscopy<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/impurity-level-confirmation-by-nuclear-magnetic-resonance-nmr-spectroscopy\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/11\/SI_Tile_6.jpg\" alt=\"Accurate determination of resin substitution in solid phase peptide synthesis\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/11\/SI_Tile_6.jpg\" alt=\"Accurate determination of resin substitution in solid phase peptide synthesis\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Accurate determination of resin substitution in solid phase peptide synthesis<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/accurate-determination-of-resin-substitution-in-solid-phase-peptide-synthesis\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/12\/SI_whitepaper_peak_purity_tile_case_study.png\" alt=\"Peak Purity of Peptides and Large Molecules by Accurate Mass LC-MS\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 612px; --smush-placeholder-aspect-ratio: 612\/612;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/12\/SI_whitepaper_peak_purity_tile_case_study.png\" alt=\"Peak Purity of Peptides and Large Molecules by Accurate Mass LC-MS\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Whitepaper<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Peak Purity of Peptides and Large Molecules by Accurate Mass LC-MS<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/peak-purity-of-peptides-and-large-molecules-by-accurate-mass-lc-ms\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/10\/almac_case_study_9.jpg\" alt=\"Mass Spectrometry: Trace Impurity Identification using Q-TOF Mass Spectroscopy\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/10\/almac_case_study_9.jpg\" alt=\"Mass Spectrometry: Trace Impurity Identification using Q-TOF Mass Spectroscopy\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Mass Spectrometry: Trace Impurity Identification using Q-TOF Mass Spectroscopy<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/mass-spectrometry-trace-impurity-identification-using-q-tof-mass-spectroscopy\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/09\/almacvoice11.jpg\" alt=\"Analytical method optimisation with Fusion QbD Software \u2013 Illustrative Case Study by Almac Sciences\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/09\/almacvoice11.jpg\" alt=\"Analytical method optimisation with Fusion QbD Software \u2013 Illustrative Case Study by Almac Sciences\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Analytical method optimisation with Fusion QbD Software \u2013 Illustrative Case Study by Almac Sciences<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--red\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/analytical-method-optimisation-with-fusion-qbd-software-illustrative-case-study-by-almac-sciences\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/06\/Ensuring-Pharmaceutical-Safety_tile_2.jpg\" alt=\"Ensuring Pharmaceutical Safety: Mass Spectrometry Approaches to Nitrosamine Analysis\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/06\/Ensuring-Pharmaceutical-Safety_tile_2.jpg\" alt=\"Ensuring Pharmaceutical Safety: Mass Spectrometry Approaches to Nitrosamine Analysis\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Poster<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Ensuring Pharmaceutical Safety: Mass Spectrometry Approaches to Nitrosamine Analysis<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--red\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/ensuring-pharmaceutical-safety-mass-spectrometry-approaches-to-nitrosamine-analysis\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/09\/Use-of-sds_tile_2.jpg\" alt=\"Use of SDS-PAGE for Residue Protein Determination\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/09\/Use-of-sds_tile_2.jpg\" alt=\"Use of SDS-PAGE for Residue Protein Determination\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Whitepaper<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Use of SDS-PAGE for Residue Protein Determination<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--red\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/use-of-sds-page-for-residue-protein-determination\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/09\/Sotax_Tile.png\" alt=\"Sotax AT MD Semi Automated Dissolution System\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/09\/Sotax_Tile.png\" alt=\"Sotax AT MD Semi Automated Dissolution System\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Sotax AT MD Semi Automated Dissolution System<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--red\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/sotax-at-md-semi-automated-dissolution-system\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/09\/Ensuring_excellence_over_encapsulation_tile.png\" alt=\"Ensuring excellence in over-encapsulation manufacture amid supply chain challenges\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 480px; --smush-placeholder-aspect-ratio: 480\/360;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/09\/Ensuring_excellence_over_encapsulation_tile.png\" alt=\"Ensuring excellence in over-encapsulation manufacture amid supply chain challenges\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Ensuring excellence in over-encapsulation manufacture amid supply chain challenges<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--red\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/ensuring-excellence-in-over-encapsulation-manufacture-amid-supply-chain-challenges\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/09\/almacvoice11.jpg\" alt=\"Determination of Peptide Chiral Purity Using Marfey\u2019s Reagent and Accurate Mass Liquid Chromatography Mass Spectrometry\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2024\/09\/almacvoice11.jpg\" alt=\"Determination of Peptide Chiral Purity Using Marfey\u2019s Reagent and Accurate Mass Liquid Chromatography Mass Spectrometry\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Determination of Peptide Chiral Purity Using Marfey\u2019s Reagent and Accurate Mass Liquid Chromatography Mass Spectrometry<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--red\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/determination-of-peptide-chiral-purity-using-marfeys-reagent-and-accurate-mass-liquid-chromatography-mass-spectrometry\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-3\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/11\/Precision-in-Biologic-Development_tile_casestudies.png\" alt=\"Precision in Biologic Development: Leveraging Orthogonal Techniques for Superior Insights\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 400px; --smush-placeholder-aspect-ratio: 400\/400;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/wp-content\/uploads\/sites\/6\/2025\/11\/Precision-in-Biologic-Development_tile_casestudies.png\" alt=\"Precision in Biologic Development: Leveraging Orthogonal Techniques for Superior Insights\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Case Study<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Precision in Biologic Development: Leveraging Orthogonal Techniques for Superior Insights<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--red\" href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/precision-in-biologic-development-leveraging-orthogonal-techniques-for-superior-insights\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                    <\/div>\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>With more than 55 years\u2019 experience, our expert teams offer a comprehensive end-to-end suite of analytical testing for a range of product types including small molecules, peptide, biologics, conjugates, potent and controlled substances. We have hundreds of success stories, innovative solutions and best-in-class service examples to share in helping to advance human health. Here are [&hellip;]<\/p>\n","protected":false},"author":1287,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1619","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Analytical solid state case studies - Analytical &amp; Solid State Services<\/title>\n<meta name=\"description\" content=\"100s of success stories, innovative solutions and best-in-class service studies that demonstrate how we are helping to advance human health.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/case-studies\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Analytical solid state case studies\" \/>\n<meta property=\"og:description\" content=\"100s of success stories, innovative solutions and best-in-class service studies that demonstrate how we are helping to advance human health.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.almacgroup.com\/analytical-solid-state\/case-studies\/\" \/>\n<meta property=\"og:site_name\" content=\"Analytical &amp; 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