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Publications

Publications

Examples of when Almac enzyme engineering technology was used to improve an enzyme

Enzyme Engineering Services

Patents

Squalene Hopene Cyclase derivatives and use thereof for producing Ambrox

Patent

Squalene Hopene Cyclase derivatives and use thereof for producing Ambrox

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Cleaning composition comprising an engineered fatty acid alpha-dioxygenase

Patent

Cleaning composition comprising an engineered fatty acid alpha-dioxygenase

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Technical Papers

Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution

Technical Publication

Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution

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Spatial requirement for PAMO for transformation of non-native linear substrate

Technical Publication

Spatial requirement for PAMO for transformation of non-native linear substrate

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Enzyme Optimization and Process Development for a Scalable Synthesis of (R)‑2-Methoxymandelic Acid

Technical Publication

Enzyme Optimization and Process Development for a Scalable Synthesis of (R)‑2-Methoxymandelic Acid

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Rational Design of a (S)-Selective-Transaminase for Asymmetric Synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine

Technical Publication

Rational Design of a (S)-Selective-Transaminase for Asymmetric Synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine

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Rational Mutagenesis of Methionine Sulfoxide Reductase

Technical Publication

Rational Mutagenesis of Methionine Sulfoxide Reductase

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Rational engineering of a carboxylesterase for the synthesis of polyesters for biomedical applications

Technical Publication

Rational engineering of a carboxylesterase for the synthesis of polyesters for biomedical applications

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Towards the enzymatic synthesis of oligonucleotides | Manufacturing Chemist

Technical Publication

Towards the enzymatic synthesis of oligonucleotides | Manufacturing Chemist

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Regio- and stereoselectivity in the CYP450BM3-catalyzed hydroxylation of complex terpenoids: a QM/MM study

Technical Publication

Regio- and stereoselectivity in the CYP450BM3-catalyzed hydroxylation of complex terpenoids: a QM/MM study

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Catalytic mechanism of phenylacetone monooxygenases for non-native linear substrates

Technical Publication

Catalytic mechanism of phenylacetone monooxygenases for non-native linear substrates

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BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions

Technical Publication

BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions

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ALDELE: All-Purpose Deep Learning Toolkits for Predicting the Biocatalytic Activities of Enzymes

Technical Publication

ALDELE: All-Purpose Deep Learning Toolkits for Predicting the Biocatalytic Activities of Enzymes

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Enzyme Screening and Engineering for N- and O-Demethylation: Key Steps in the Synthesis of Buprenorphine

Technical Publication

Enzyme Screening and Engineering for N- and O-Demethylation: Key Steps in the Synthesis of Buprenorphine

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