Published Papers

Explore our collection of technical papers showcasing Almac Science’s expertise in Custom and Flow Chemistry. These publications highlight innovative approaches, practical insights, and real-world applications that support efficient route development, scalable manufacturing, and complex chemical challenges. Access expert-led research designed to help advance your projects with confidence.

Technical Publication

A pharma perspective on sustainability advantages through adoption of continuous flow

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Technical Publication

Continuous-Flow Synthesis of Cyclobutenes Using LED Technology

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Technical Publication

Continuous-flow transfer hydrogenation of benzonitrile using formate as a safe and sustainable source of hydrogen

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Technical Publication

Tandem Continuous Flow Curtius Rearrangement and Subsequent Enzyme-Mediated Impurity Tagging

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Technical Publication

FAST Hydrogenations as a Continuous Platform for Green Aromatic Nitroreductions

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Technical Publication

A Perspective on Continuous Flow Chemistry in the Pharmaceutical Industry

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Technical Publication

Continuous flow photooxidation of alkyl benzenes using fine bubbles for mass transfer enhancement

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Technical Publication

Overcoming the Hurdles and Challenges Associated with Developing Continuous Industrial Processes

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Technical Publication

Coupling biocatalysis with high-energy flow reactions for the synthesis of carbamates and β-amino acid derivatives

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Technical Publication

Evaluating the Green Credentials of Flow Chemistry towards Industrial Applications

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Technical Publication

Interrupted Curtius Rearrangements of Quaternary Proline Derivatives: A Flow Route to Acyclic Ketones and Unsaturated Pyrrolidines

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Technical Publication

Coupling biocatalysis with high-energy flow reactions for the synthesis of carbamates and β-amino acid derivatives

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Technical Publication

Modular Synthesis of Benzoylpyridines Exploiting a Reductive Arylation Strategy

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Technical Publication

Oxidation of Alcohols and Aldehydes with Peracetic Acid and a Mn(II)/Pyridin-2-Carboxylato Catalyst: Substrate and Continuous Flow Studies

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Technical Publication

Development and Scale-Up of 7‑COOH CBD Synthesis, a Key Cannabinoid Metabolite

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Technical Publication

Multiphase photochemistry in flow mode via an integrated continuous stirred tank reactor (CSTR) approach

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Technical Publication

Continuous Flow Approach for Benzylic Photo-oxidations Using Compressed Air

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Technical Publication

Chemoselective oxidative N-debenzylation of aryl halogenated amines using the Laccase LAC97/TEMPO system

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Technical Publication

Structurally Diverse Nitrogen-Rich Scaffolds via Continuous Photo Click Reactions

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Technical Publication

Continuous Flow Synthesis of β-Aminoketones as Masked Vinyl Ketone Equivalents

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Technical Publication

A Sustainable-by-Design Process for the Selective Photooxidation of Ethylbenzene in a Scalable Agitated Baffle Reactor

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Technical Publication

Tandem continuous-flow α-C-H functionalisation of pyrrolidine with aryl bromide-derived organolithium reagents

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Technical Publication

The Impact of Continuous Flow Technology and Collaboration between Academia and Industry

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Technical Publication

Ritter reactions in continuous flow catalysed by a solid-supported sulfonic acid catalyst

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