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Radiolabelling for Complex Development Programmes

Supporting drug development with specialist ¹⁴C radiolabelling expertise, from challenging syntheses to GMP manufacture.

Speak to a Radiolabelling Expert

¹⁴C Radiolabelling

Understanding how a molecule is absorbed, distributed, metabolised and excreted is a critical part of drug development. Generating radiolabelled materials to support these studies often presents significant scientific and technical challenges, particularly when complex structures, limited starting materials or demanding timelines are involved.

At Almac Sciences, we combine specialist radiochemistry expertise with integrated analytical, quality and manufacturing capabilities to deliver robust radiolabelling solutions. From early development through to GMP manufacture, we help customers overcome the synthetic and regulatory challenges associated with producing high-quality radiolabelled materials.

Whether supporting human ADME studies, metabolite investigation or the development of labelled peptides and bioconjugates, our teams work collaboratively to identify practical solutions that meet programme objectives while maintaining quality, compliance and delivery expectations. The service includes non-GMP and GMP radiolabelling, metabolite synthesis, peptide and bioconjugate labelling, supported by integrated analytical, QC and QA expertise.

We are MHRA certified for  ¹⁴C manufacture and GMP compliance and we are fully equipped to deliver an industry-leading, cost-effective radiolabelling service.

Our strong track record in providing a complete suite of custom Radiolabelling solutions include:

Biology & fermentation expertise
QC & analytical support
Stability studies & storage advice
GMP & non-GMP stable & 14C-labelled API synthesise
QC & analytical support selectAZymeTM enzymes for selective and mild transformation
Labelled metabolites
Storage & repurification

Our highly skilled team are enabled to offer custom radiolabelling services within a dedicated controlled access GMP facility using validated quality-critical equipment including: