{"id":50875,"date":"2020-02-03T15:24:01","date_gmt":"2020-02-03T15:24:01","guid":{"rendered":"https:\/\/www.almacgroup.com\/api-chemical-development\/?page_id=50875"},"modified":"2021-09-21T09:50:29","modified_gmt":"2021-09-21T08:50:29","slug":"metabolites","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/api-chemical-development\/metabolites\/","title":{"rendered":"Metabolites"},"content":{"rendered":"\n<h4 class=\"wp-block-heading\">Metabolite synthesis is another tool within selectAZyme\u2019s<sup>TM<\/sup>&nbsp;service offering that provides access to both oxidative and glycosylated products. Almac has implemented state-of-the-art biocatalytic technology for rapid metabolite synthesis, isolation and structural identification.<\/h4>\n\n\n\n<p>We have&nbsp;developed both recombinant and microbial P<sub>450<\/sub>&nbsp;technology to access metabolites from mg to 100s grams scale.&nbsp; These enzymes, which mimic human P<sub>450<\/sub>&nbsp;systems, are a powerful tool for accessing difficult to synthesise metabolites rapidly.<\/p>\n\n\n\n<p><strong>Metabolite Synthesis<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Cloned Human P<sub>450<\/sub><\/li><li>Cloned Microbial P<sub>450<\/sub><\/li><li>Extensive microbial collection<\/li><\/ul>\n\n\n\n<p><strong>Metabolite Isolation\/Structure ID<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Analytical and prep LC<\/li><li>LC\/MS<\/li><li>High-field NMR<\/li><\/ul>\n\n\n\n<p>Almac\u2019s scale-up ability allows us to rapidly take \u2018hits\u2019 from conception to gram delivery as and when our customers require the products.<\/p>\n\n\n\n<p>In addition, Almac can also supply radiolabelled metabolites utilising our in-house isotope chemistry group.<\/p>\n\n\n\n<p><a class=\"c-btn c-btn--red\" href=\"https:\/\/www.almacgroup.com\/api-chemical-development\/contact-us\/\">Contact us<\/a><\/p>\n\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>Metabolite synthesis is another tool within selectAZyme\u2019sTM&nbsp;service offering that provides access to both oxidative and glycosylated products. Almac has implemented state-of-the-art biocatalytic technology for rapid metabolite synthesis, isolation and structural identification. We have&nbsp;developed both recombinant and microbial P450&nbsp;technology to access metabolites from mg to 100s grams scale.&nbsp; These enzymes, which mimic human P450&nbsp;systems, are a [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-50875","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Metabolites - API Services &amp; Chemical Development<\/title>\n<meta name=\"description\" content=\"Almac has implemented state-of-the-art biocatalytic technology for rapid metabolite synthesis, isolation and structural identification.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/api-chemical-development\/metabolites\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Metabolites\" \/>\n<meta property=\"og:description\" content=\"Almac has implemented state-of-the-art biocatalytic technology for rapid metabolite synthesis, isolation and structural identification.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.almacgroup.com\/api-chemical-development\/metabolites\/\" \/>\n<meta property=\"og:site_name\" content=\"API Services &amp; 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