{"id":50888,"date":"2020-02-03T15:32:27","date_gmt":"2020-02-03T15:32:27","guid":{"rendered":"https:\/\/www.almacgroup.com\/api-chemical-development\/?page_id=50888"},"modified":"2025-11-19T09:28:22","modified_gmt":"2025-11-19T09:28:22","slug":"modified-histones","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/api-chemical-development\/modified-histones\/","title":{"rendered":"Modified Histones"},"content":{"rendered":"\n<div class=\"wp-block-image\"><figure class=\"alignright size-large is-resized\"><img decoding=\"async\" data-src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-910x1024.jpg\" alt=\"Modified Histones\" class=\"wp-image-51007 lazyload\" width=\"228\" height=\"256\" data-srcset=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-910x1024.jpg 910w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-267x300.jpg 267w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-768x864.jpg 768w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-1365x1536.jpg 1365w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-1820x2048.jpg 1820w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000.jpg 2000w\" data-sizes=\"(max-width: 228px) 100vw, 228px\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 228px; --smush-placeholder-aspect-ratio: 228\/256;\" \/><noscript><img decoding=\"async\" src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-910x1024.jpg\" alt=\"Modified Histones\" class=\"wp-image-51007\" width=\"228\" height=\"256\" srcset=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-910x1024.jpg 910w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-267x300.jpg 267w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-768x864.jpg 768w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-1365x1536.jpg 1365w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000-1820x2048.jpg 1820w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2020\/02\/histones-assembled-large-mods-v3-2000.jpg 2000w\" sizes=\"(max-width: 228px) 100vw, 228px\" \/><\/noscript><\/figure><\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-regulating-regular-and-disease-specific-cellular-processes\">Regulating Regular and Disease-Specific Cellular Processes<\/h4>\n\n\n\n<p>Our proprietary platform technologies for the chemical synthesis of proteins enable the provision of pure, full-length natural histones, containing a wide variety of post-translational modifications, at any specified site(s) within the protein.<\/p>\n\n\n\n<p>Our synthetic modified histones correspond exactly to the sequences of the natural modified histones, containing no amino acid replacements or residue analogues. They can be used in a variety of applications, such as substrates for specific histone modification enzymes, protein binding assays, and the generation of chromatin preparations.<\/p>\n\n\n\n<div class=\"c-table-responsive\">\n<figure class=\"wp-block-table\"><table class=\"c-table--img\"><thead><tr class=\"u-bg-table--black\"><td><strong>Chemokine Name<\/strong><\/td><td><strong>Size<\/strong><\/td><td><strong>Catalogue code<\/strong><br>(Click to visit shop)<\/td><\/tr><\/thead><tbody><tr><td>H3 native<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-0001<\/a><\/td><\/tr><tr><td>H3 K9me<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3k9me-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-1002<\/a><\/td><\/tr><tr><td>H3 K9ac K14ac<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3k9ack14ac-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-3001 <\/a><\/td><\/tr><tr><td>H3 K9me2<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3k9me2-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-1003<\/a><\/td><\/tr><tr><td>H3 K4ac K9ac K14ac K18ac K23ac<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3k4ack9ack14ack18ack23ac-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-3003<\/a><\/td><\/tr><tr><td>H3 K9me3<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3k9me3-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-1004<\/a><\/td><\/tr><tr><td>H3 S10p K14ac<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3s10pk14ac-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-3002<\/a><\/td><\/tr><tr><td>H3 K4me3<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3k4me3-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-1001&nbsp;<\/a><\/td><\/tr><tr><td>H3 S10p<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3r2me3-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-4001<\/a><\/td><\/tr><tr><td>H3 R2me<\/td><td>25ug<\/td><td><a href=\"https:\/\/shop.almacgroup.com\/histone-h3r2me3-synthetic-25ug\" target=\"_blank\" rel=\"noreferrer noopener\">AH3-2001<\/a><\/td><\/tr><\/tbody><\/table><\/figure><\/div>\n\n<style>\n.wp-block-table {\n      overflow-x: visible;\n  }\n.wp-block-table table td a {\n    color: #e63329;\n    text-decoration: underline;\n}\n.c-table--img {\nbackground-image: none !important;\ncolor: #1d1d1b !important;\n}\n.c-table--img thead td {\nborder-bottom: 1px solid #cfcfcf !important;\n}\n.c-table--img tbody td {\nborder: 1px solid #cfcfcf !important;\n}\n@media only screen and (max-width: 768px) {\n  .wp-block-table {\n      overflow-x: auto;\n  }\n}\n<\/style>\n\n\n<div class=\"o-wrapper\">\n\t<div class=\"o-grid\">\n\n\t\t<div class=\"o-grid__item u-width-full u-align-center\">\n\t\t\t\t\t\t\t<h2 class=\"u-m-b4\">Related Resources<\/h2>\n\t\t\t\t\t<\/div>\n\n\t<\/div>\n            <div class=\"o-grid u-flex-align-stretch u-m-b3\">\n\n            \n                                            <article class=\"o-grid__item u-width-4\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-center u-align-center u-p-x4 u-p-y3 u-m-b2\">\n                \n                                                <img decoding=\"async\" class=\"u-m-b2 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2021\/08\/peptides-catalogue-scaled-1.jpeg\" alt=\"Solid Phase Peptide Synthesis of Full-Length Modified Histones\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 2560px; --smush-placeholder-aspect-ratio: 2560\/1714;\"><noscript><img decoding=\"async\" class=\"u-m-b2\" src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2021\/08\/peptides-catalogue-scaled-1.jpeg\" alt=\"Solid Phase Peptide Synthesis of Full-Length Modified Histones\"><\/noscript>\n                        \n                                                    <p class=\"c-resource__category\">Poster<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Solid Phase Peptide Synthesis of Full-Length Modified Histones<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-primary c-btn--none\" href=\"https:\/\/almacgroup.com\/knowledge\/library\/solid-phase-peptide-synthesis-of-full-length-modifies-histones\/\" target=\"\">Read more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                    <\/div>\n    <\/div>\n\n\n<div class=\"o-wrapper\">\n\t<div class=\"o-grid\">\n\n\t\t<div class=\"o-grid__item u-width-full \">\n\t\t\t\t\t<\/div>\n\n\t<\/div>\n    <\/div>\n\n\n\n<h4 class=\"wp-block-heading\" id=\"h-complete-the-form-below-to-make-an-enquiry\">Complete the form below to make an enquiry<\/h4>\n\n\n\n","protected":false},"excerpt":{"rendered":"<p>Regulating Regular and Disease-Specific Cellular Processes Our proprietary platform technologies for the chemical synthesis of proteins enable the provision of pure, full-length natural histones, containing a wide variety of post-translational modifications, at any specified site(s) within the protein. Our synthetic modified histones correspond exactly to the sequences of the natural modified histones, containing no amino [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-50888","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Modified Histones - API Services &amp; Chemical Development<\/title>\n<meta name=\"description\" content=\"Our proprietary platform technologies for the chemical synthesis of proteins enable the provision of pure, full-length natural histones.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/api-chemical-development\/modified-histones\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Modified Histones\" \/>\n<meta property=\"og:description\" content=\"Our proprietary platform technologies for the chemical synthesis of proteins enable the provision of pure, full-length natural histones.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.almacgroup.com\/api-chemical-development\/modified-histones\/\" \/>\n<meta property=\"og:site_name\" content=\"API Services &amp; 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