{"id":52993,"date":"2023-02-02T15:26:39","date_gmt":"2023-02-02T15:26:39","guid":{"rendered":"https:\/\/www.almacgroup.com\/api-chemical-development\/?page_id=52993"},"modified":"2026-04-02T10:15:49","modified_gmt":"2026-04-02T09:15:49","slug":"insight-enzyme-databases","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/api-chemical-development\/insight-enzyme-databases\/","title":{"rendered":"INSIGHT enzyme databases"},"content":{"rendered":"<!-- thirds_media_text.php -->\n<!-- Two thirds text, One third Media -->\n<section class=\"u-bg-white t-theme-component-overwrite\"  id=\"thirdsMediaBlock\">\n\t<div class=\"c-half-media-text\">\n\t\t<div class=\"o-wrapper\">\n\t\t\t\n\t\t\t\t\t\n\t\t\t\t\t\t<article class=\"o-grid \">\n\t\t\t\t\t\t\t<div class=\"u-width-2\/3 u-width-full@m c-half-media__repeat-text none u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Almac has developed a new platform called INSIGHT (<strong>IN<\/strong> <strong>S<\/strong>ilico <strong>I<\/strong>nformed meta<strong>G<\/strong>enomic <strong>H<\/strong>arvesting Technology) with the support for research and development from Invest Northern Ireland under the European Union\u2019s Investment for Growth and Jobs Programme.<\/p>\n<p>With the increased attraction of biocatalysis as a sustainable alternative to traditional chemical synthesis, the need for shortened development times arises. Almac\u2019s new INSIGHT platform has been specifically designed to reduce timelines and cost for development of specific and sustainable biocatalysts.<\/p>\n<div class=\"u-hidden@m\">\n<p><img decoding=\"async\" width=\"1280\" height=\"720\" class=\"alignnone size-medium wp-image-53511 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1.jpg\" alt=\"\" data-srcset=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1.jpg 1280w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-300x169.jpg 300w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-1024x576.jpg 1024w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-768x432.jpg 768w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-996x560.jpg 996w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-480x270.jpg 480w\" data-sizes=\"(max-width: 1280px) 100vw, 1280px\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 1280px; --smush-placeholder-aspect-ratio: 1280\/720;\" \/><noscript><img decoding=\"async\" width=\"1280\" height=\"720\" class=\"alignnone size-medium wp-image-53511\" src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1.jpg\" alt=\"\" srcset=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1.jpg 1280w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-300x169.jpg 300w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-1024x576.jpg 1024w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-768x432.jpg 768w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-996x560.jpg 996w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Figure-1-480x270.jpg 480w\" sizes=\"(max-width: 1280px) 100vw, 1280px\" \/><\/noscript><\/p>\n<\/div>\n<div class=\"u-hidden u-block@m u-m-b3@m\"><img decoding=\"async\" width=\"600\" height=\"1023\" class=\"alignnone size-medium wp-image-53512 lazyload\" data-src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2.png\" alt=\"\" data-srcset=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2.png 600w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2-176x300.png 176w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2-328x560.png 328w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2-188x320.png 188w\" data-sizes=\"(max-width: 600px) 100vw, 600px\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 600px; --smush-placeholder-aspect-ratio: 600\/1023;\" \/><noscript><img decoding=\"async\" width=\"600\" height=\"1023\" class=\"alignnone size-medium wp-image-53512\" src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2.png\" alt=\"\" srcset=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2.png 600w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2-176x300.png 176w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2-328x560.png 328w, https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/NEW-Intro-2-188x320.png 188w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><\/noscript><\/div>\n<p>The new INSIGHT platform hosts metagenomic and bioinformatic enzyme discovery, high throughput screening, in <em>silico<\/em> enzyme engineering and machine learning to identify and engineer new biocatalysts. These techniques enable the development of more robust enzymes to displace multi-step chemical routes by simpler, low cost and greener enzymatic processes.<\/p>\n<p>To expedite the INSIGHT platform, Almac integrates library synthesis into its multi-level enzyme engineering platform which shortens timelines and makes the accelerated development of genes-to-GMP more affordable.<\/p>\n<p>The basic concept of INSIGHT is to improve the enzyme discovery process project initiation which shortens timelines for our customers. INSIGHT is composed of the following enzyme discovery pipelines:<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"u-width-1\/3 u-width-full@m c-half-media__repeat-image\">\n\t\t\t\t                <!-- \n-->\n\n\n\t\t\t\t\t\t\t\t\t<img decoding=\"async\" data-src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2023\/02\/Screenshot-2023-02-02-at-15.22.46-e1775121340878.png\" alt=\"\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" class=\"lazyload\" style=\"--smush-placeholder-width: 175px; --smush-placeholder-aspect-ratio: 175\/74;\"><noscript><img decoding=\"async\" src=\"https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2023\/02\/Screenshot-2023-02-02-at-15.22.46-e1775121340878.png\" alt=\"\"><\/noscript>\n\t\t\t\t                \t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/article>\n\n\t\t\t\t\t\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/section>\n\n\n<!-- TX1 title-image.php -->\n\t\t\t<div class=\"c-box-link-title-image below bottom panel-grey strip-none standard centre\">\n\t\t\t<div class=\"o-wrapper\">\n\t\t\t\t<div class=\"o-grid u-flex-align-stretch\">\n\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t<h2 class=\"u-p-b4 u-a-center\"><\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"o-grid u-flex-align-stretch u-m-b6@m u-overflow-hidden u-overflow-initial@l o-grid--center\">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"o-grid__item u-width-4\/12 u-width-6\/12@m u-width-full@s\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- Show the correct button based off pop up to show or not -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/api-chemical-development\/insight-enzyme-databases\/smart-enzyme-discovery\/\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<header class=\"c-link-box__image c-link-box__remove-bg lazyload\" \n                                                                        role=\"img\" aria-label=\"\" \n                                                                        style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/smart-enzyme-discovery_updated.jpg&#039;)\">\n   \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/header>\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"c-link-box__content strip-none\">\n\t\t\t\t\t\t\t\t\t\t<div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"u-m-b2\">Smart enzyme discovery<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-m-b2\">\n\t\t\t\t\t\t\t\t\t\t\t\tUsing molecular modelling tools and Almac&#8217;s bioinformatic algorithms to discover new enzymes for desired reactions.\u2028\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\n\n    <div class=\"  u-m-t-auto \">\n                            <div class=\"c-btn c-btn-secondary c-btn--red\">Find out more<\/div>\n                    <\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<!-- Only show pop up if acf is checked to show it -->\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t<\/article>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"o-grid__item u-width-4\/12 u-width-6\/12@m u-width-full@s\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- Show the correct button based off pop up to show or not -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/api-chemical-development\/insight-enzyme-databases\/metagenomics-enzyme-discovery\/\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<header class=\"c-link-box__image c-link-box__remove-bg lazyload\" \n                                                                        role=\"img\" aria-label=\"\" \n                                                                        style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/Metagenomics-enzyme-discovery.jpg&#039;)\">\n   \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/header>\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"c-link-box__content strip-none\">\n\t\t\t\t\t\t\t\t\t\t<div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"u-m-b2\">Metagenomics enzyme discovery<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-m-b2\">\n\t\t\t\t\t\t\t\t\t\t\t\tUsing the sequence space of unique proprietary metagenomics databases to discover new enzymes for desired reactions.\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\n\n    <div class=\"  u-m-t-auto \">\n                            <div class=\"c-btn c-btn-secondary c-btn--red\">Find out more<\/div>\n                    <\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<!-- Only show pop up if acf is checked to show it -->\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t<\/article>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"o-grid__item u-width-4\/12 u-width-6\/12@m u-width-full@s\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- Show the correct button based off pop up to show or not -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/api-chemical-development\/insight-enzyme-databases\/ai-assisted-enzyme-discovery-2\/\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<header class=\"c-link-box__image lazyload\" \n                                                                        role=\"img\" aria-label=\"\" \n                                                                        style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/enzyme1_optimise-scaled-1.jpg&#039;)\">\n   \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/header>\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"c-link-box__content strip-none\">\n\t\t\t\t\t\t\t\t\t\t<div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"u-m-b2\">AI-assisted enzyme discovery <\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-m-b2\">\n\t\t\t\t\t\t\t\t\t\t\t\tUsing machine learning and deep learning to discover new enzymes with desired properties.\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\n\n    <div class=\"  u-m-t-auto \">\n                            <div class=\"c-btn c-btn-secondary c-btn--red\">Find out more<\/div>\n                    <\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<!-- Only show pop up if acf is checked to show it -->\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t<\/article>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"o-grid__item u-width-4\/12 u-width-6\/12@m u-width-full@s\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- Show the correct button based off pop up to show or not -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/api-chemical-development\/insight-enzyme-databases\/enzyme-expression-improvement-platform-2\/\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<header class=\"c-link-box__image c-link-box__remove-bg lazyload\" \n                                                                        role=\"img\" aria-label=\"\" \n                                                                        style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/09\/enzyme2_optimise-scaled-1.jpg&#039;)\">\n   \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/header>\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"c-link-box__content strip-none\">\n\t\t\t\t\t\t\t\t\t\t<div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"u-m-b2\">Enzyme expression improvement platform<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-m-b2\">\n\t\t\t\t\t\t\t\t\t\t\t\tUsing INSIGHT technology to improve the expression platform.\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\n\n    <div class=\"  u-m-t-auto \">\n                            <div class=\"c-btn c-btn-secondary c-btn--red\">Find out more<\/div>\n                    <\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<!-- Only show pop up if acf is checked to show it -->\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t<\/article>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"o-grid__item u-width-4\/12 u-width-6\/12@m u-width-full@s\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- Show the correct button based off pop up to show or not -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/knowledge\/library\/almac-sciences-insight-platform-accelerates-genes-to-gmp-implementation\/\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<header class=\"c-link-box__image lazyload\" \n                                                                        role=\"img\" aria-label=\"\" \n                                                                        style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/api-chemical-development\/wp-content\/uploads\/sites\/4\/2024\/10\/INSIGHT-whitepaper-tile.jpg&#039;)\">\n   \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/header>\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"c-link-box__content strip-none\">\n\t\t\t\t\t\t\t\t\t\t<div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 class=\"u-m-b2\">Almac Sciences\u2019 INSIGHT Platform Whitepaper<\/h4>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-m-b2\">\n\t\t\t\t\t\t\t\t\t\t\t\tAlmac Sciences\u2019 INSIGHT Platform Accelerates Genes-to-GMP Implementation\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\n\n    <div class=\"  u-m-t-auto \">\n                            <div class=\"c-btn c-btn-secondary c-btn--red\">Find out more<\/div>\n                    <\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<!-- Only show pop up if acf is checked to show it -->\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t<\/article>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article 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