Synthesis of 14C-Labelled Peptide
The approach taken for a client who trusted Almac for the manufacture and supply of 14C-labelled antibody drug conjugate for their drug development programme.
New Technology Enables Primary and Secondary Screening of Broad Panels
Graham Cotton of Almac & Wayne Bowen of TTP Labtech
Published in GEN News 10th May 2013
Luminescence and fluorescence based assay methods prevail in modern HTS. Although invaluable as technologies, the problem of compound-related assay interferences such as quenching, auto-fluorescence, and light scattering becomes important.
The degree of interference experienced may depend on variables such as assay reagents, composition of the chemical library, and reader technology.