Like many other companies and institutions around the world, we are experiencing interference with some of our systems within the TNT network.
We are implementing remediation steps as quickly as possible. We have implemented operational contingencies to continue to complete collections from customers with scheduled stops. For customers who do not have a regular stop, collection should be arranged via our customer service centers.
Customers may experience delays in the transit of shipments, particularly inter-continental or non-EU European delivery, as we work to remediate our systems. Additionally, if customers do not have the facility for self-labeling, they may also experience delays.
We are not able to collect shipments of dangerous goods at this time.
We regret any inconvenience to our customers.
Conducting many of the industry’s most complex studies We are pioneers in adaptive and other dynamic randomisation techniques. To assist you in the design and implementation of dynamic randomisation and dose titration schemes, our in-house statisticians offer upfront consultancy during the planning phase. Their expertise will also be applied throughout your study’s life cycle to ensure its successful execution. Numerous randomisation methodologies via IXRS®:
- Permuted block list approaches (central, simple through to complex stratification)
- Covariate adaptive (dynamic) randomisation methodologies, including:
- Pocock and Simon minimisation with biased-coin assignment
- Dynamic hierarchical methodologies
- Custom methodologies
- Adaptive trial designs
Adaptive trial designs Well-designed adaptive trials result in lower drug development costs, reduced timings, faster decisions and improved patient safety. IXRS® and eCOA tools capture safety and efficacy data and make it viewable in real-time – providing sponsors with the information they need, when they need it quickly. We have implemented more than 100 adaptive studies and established a reputation as a market leader in adaptive trial designs including:
- Fixed interim designs
- Bayesian response adaptive algorithms