{"id":1229,"date":"2020-03-20T16:45:22","date_gmt":"2020-03-20T16:45:22","guid":{"rendered":"https:\/\/www.almacgroup.com\/diagnostics\/?page_id=1229"},"modified":"2026-03-04T08:16:27","modified_gmt":"2026-03-04T08:16:27","slug":"dna-sequencing-solutions","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/diagnostics\/global-laboratories\/platforms-technologies\/dna-sequencing-solutions\/","title":{"rendered":"DNA-Sequencing Solutions"},"content":{"rendered":"\n<div style=\"height:34px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"block-7bde669d-d178-4731-b8f1-2b120ecc3a98\">Background Information<\/h3>\n\n\n\n<p id=\"block-75d1f825-9e9c-4a99-a545-36035180e989\">Almac Diagnostic Services has implemented a range of comprehensive next-generation sequencing (NGS) solutions including large panels, mid-size panels and bespoke single gene assays.&nbsp; These multiple solutions are analysed using the Illumina MiSeq, NextSeq500, NextSeq550, NovaSeq6000 and NovaSeq X Plus <strong><a href=\"https:\/\/almacgroup.com\/diagnostics\/our-services\/platforms-technologies\/\">sequencing platforms<\/a><\/strong>.&nbsp; Our DNA-Sequencing solutions support novel <strong><a href=\"https:\/\/almacgroup.com\/diagnostics\/genomic-services\/\">biomarker discovery<\/a><\/strong> through to<strong> <a href=\"https:\/\/almacgroup.com\/diagnostics\/clinical-trial-assays\/\">prospective clinical trial use<\/a><\/strong>, supported by Almac innovative proprietary<strong>&nbsp;<a href=\"https:\/\/almacgroup.com\/diagnostics\/supporting-services\/data-sciences\/\">bioinformatics<\/a><\/strong> solutions.<\/p>\n\n\n\n&nbsp;\n&nbsp;\n\n<div class=\"u-hidden@s\">\n  <svg version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" viewBox=\"0 0 2584 1584\">\n    <image width=\"2584\" height=\"1584\" 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u-align-left@m\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t<div class=\"u-m-t2\">\n\t\t\t\t\t<div class=\"c-accordion js-accordion\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item1\" class=\"c-accordion__item u-c-mid-grey accordion-1\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">TruSight\u2122 Oncology 500<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p><strong><span style=\"color: #00b0f0;\">TruSight\u2122 Oncology 500<\/span><\/strong><\/p>\n<p><strong>The Platform<\/strong>:\u00a0 The TSO-500 panel targets <strong>DNA and RNA variants<\/strong> for assessment of <strong>523 genes, <\/strong>including RNA fusions from <strong>55 genes<\/strong>, in the same solid tumour sample.\u00a0 In addition, it accurately measures the key immunotherapy biomarkers: tumour mutation burden <strong>(TMB)<\/strong> and microsatellite instability <strong>(MSI)<\/strong>.<\/p>\n<p><strong><span style=\"color: #00b0f0;\">Features &amp; Benefits:<\/span><\/strong><\/p>\n<ul>\n<li><strong>Pan-cancer content<\/strong> aligned with key guidelines and clinical trials<\/li>\n<li><strong>Tumour-only workflow<\/strong> for simplicity and efficiency<\/li>\n<li>TMB calling performance similar to whole-exome sequencing (WES) panels<\/li>\n<li>Large 1.94 Mb panel and <strong>sophisticated algorithm for accurate TMB score<\/strong><\/li>\n<li><strong>A solution that can be kit-able in future<\/strong> to <strong>support multiple CDx tests<\/strong><\/li>\n<\/ul>\n<div class=\"c-diag-table-wrap\">\n<table class=\"u-table\">\n<tbody>\n<tr>\n<th style=\"background-color: #00b0f0;\">Metric<\/th>\n<th style=\"background-color: #00b0f0;\">TSO-500 Solution<\/th>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Chemistry<\/td>\n<td style=\"width: 303px;\">Illumina TruSight\u2122 Oncology 500<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Tissue Type<\/td>\n<td style=\"width: 303px;\">FFPE (compatible with other sample types on request)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Recommended Tissue Requirements<\/td>\n<td style=\"width: 303px;\">For FFPE, tissue should be macrodissected<br \/>\n10 x 5 \u00b5m FFPE sections with a tissue area &gt;1cm<sup>2<\/sup> and high tumour content &gt;10% viable cells<br \/>\nSpecific tissue guidelines will be provided on a per-project basis<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Recommended DNA Input<\/td>\n<td style=\"width: 303px;\">Recommended sample input 120 ng, minimum 40 ng<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Standard Sequencing Specification<\/td>\n<td style=\"width: 303px;\">Minimum 200X coverage<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Deliverables<\/td>\n<td style=\"width: 303px;\">FASTQ, VCF, TMB &amp; MSI Scores and QC Report as standard. BAM files available on request<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item2\" class=\"c-accordion__item u-c-mid-grey accordion-2\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">Whole Genome Sequencing (WGS) Service<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>A high quality, robust Next Generation Sequencing (NGS) solution built on Roche\u2019s platform. Almac&#8217;s wet lab optimised workflow generates comprehensive WGS data from blood. The platform covers coding and non-coding regions with readily interpretable raw sequencing data for use in biomarker discovery and retrospective clinical investigation.<\/p>\n<p><strong><span style=\"color: #00b0f0;\">Features &amp; Benefits:<\/span><\/strong><\/p>\n<ul>\n<li><strong>QC guarantee of 30X mean target coverage<\/strong> across sample cohort ensures comprehensive downstream analysis and data interpretation<\/li>\n<li>Protocol <strong>optimised for blood samples<\/strong><\/li>\n<li><strong>Interactive QC report<\/strong> enables rapid and comprehensive sample quality interrogation across the cohort<\/li>\n<li><strong>Raw Sequence data<\/strong> delivered in FASTQ format, compatible with the majority of bioinformatics pipelines<\/li>\n<li><strong>Germline variant discovery service: <\/strong>filtered and annotated germline variants delivered as standard VCF files compatible with majority of downstream interpretation tools.<\/li>\n<\/ul>\n<div class=\"c-diag-table-wrap\">\n<table>\n<tbody>\n<tr>\n<th style=\"background-color: #00b0f0;\"><strong>Metric<\/strong><\/th>\n<th style=\"background-color: #00b0f0;\"><strong>WGS Solution<\/strong><\/th>\n<\/tr>\n<tr>\n<td>Chemistry<\/td>\n<td>Roche KAPA HyperPrep (PCR-Free)<\/td>\n<\/tr>\n<tr>\n<td>Sample Type<\/td>\n<td>Optimised for blood<\/td>\n<\/tr>\n<tr>\n<td>Recommended Sample Requirements<\/td>\n<td>2ml EDTA Blood<\/td>\n<\/tr>\n<tr>\n<td>Recommended DNA Input<\/td>\n<td>Minimum recommended input of 250ng DNA from blood samples<\/td>\n<\/tr>\n<tr>\n<td>Standard Sequencing Specification<\/td>\n<td>30X mean target coverage<\/td>\n<\/tr>\n<tr>\n<td>Deliverables<\/td>\n<td>FASTQ files<br \/>\nExcel compatible report, detailing lab, pre &amp; post alignment QC<br \/>\nHTML interactive report allowing simultaneous assessment of sequence QC data from multiple samples.<br \/>\nGermline variant discovery service including variant filtering and annotation offered as standard.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p style=\"text-align: center;\"><span style=\"font-family: 'trebuchet ms', geneva; font-weight: bold;\"><a style=\"color: #ffffff; background: #00b0f0; text-decoration: none; border: 2px solid #00b0f0; border-radius: 4px; padding: 8px 14px; font-size: 18px;\" href=\"https:\/\/www.almacgroup.com\/diagnostics\/whole-genome-sequencing-wgs-service\/\" rel=\" noopener\">Find out more<\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item3\" class=\"c-accordion__item u-c-mid-grey accordion-3\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">Whole Genome Methylation Sequencing (WGMS) Service<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>&nbsp;<\/p>\n<p>A high quality, robust Next Generation Sequencing (NGS) solution built on New England Biolab\u2019s enzymatic methylation sequencing platform (EM-seq). Almac\u2019s wet lab optimised workflow generates comprehensive WGMS data from fresh frozen (FF) samples. The platform covers coding and non-coding regions, generating raw sequencing data for use in biomarker discovery and retrospective clinical investigation. Optional bioinformatics services include processing of raw sequencing data to generate readily interpretable CpG site methylation profiles, and fully customised downstream analysis and reporting solutions.<\/p>\n<p><strong><span style=\"color: #00b0f0;\">Features &amp; Benefits:<\/span><\/strong><\/p>\n<p>QC guarantee of 30X mean target coverage across sample cohort enables comprehensive downstream analysis and data interpretation.<\/p>\n<ul>\n<li>EM-Seq methodology allows for more uniform coverage of CpG site methylation sites.<\/li>\n<li>Protocol optimised for fresh frozen tissue samples.<\/li>\n<li>Interactive QC report enables rapid and comprehensive sample quality interrogation across the cohort.<\/li>\n<li>Raw Sequence data delivered in FASTQ format, compatible with the majority of bioinformatics pipelines for processing and interpreting Em-Seq data.<\/li>\n<li>Optional bioinformatics services to generate readily interpretable CpG site methylation profiles, and fully customised downstream analysis and reporting solutions<\/li>\n<\/ul>\n<div class=\"c-diag-table-wrap\">\n<p>Recommended DNA Input200ng DNA from FF samples.<\/p>\n<table>\n<tbody>\n<tr>\n<th style=\"background-color: #00b0f0;\"><strong>Metric<\/strong><\/th>\n<th style=\"background-color: #00b0f0;\"><strong>WGMS Solution<\/strong><\/th>\n<\/tr>\n<tr>\n<td>Chemistry<\/td>\n<td>New England Biolabs NEBNext Enzymatic Methyl-Seq (EM-Seq\u2122).<\/td>\n<\/tr>\n<tr>\n<td>Tissue Type<\/td>\n<td>Optimised for Fresh Frozen (FF) samples.<\/td>\n<\/tr>\n<tr>\n<td>Standard Sequencing Specification<\/td>\n<td>30X average on target coverage across cohort (sample quality dependent).<\/td>\n<\/tr>\n<tr>\n<td>Deliverables<\/td>\n<td>FASTQ and\/or BAM files.\u2028Excel compatible report, detailing lab, pre &amp; post alignment QC.<\/p>\n<ul>\n<li>Scalable WGMS pipeline hosted on the Illumina Connected Analytics (ICA) cloud platform enabling:<\/li>\n<li>Pre &amp; post alignment QC (standard).<\/li>\n<li>CpG site methylation profiling delivered in bedGraph format (optional).<\/li>\n<li>Custom downstream analysis &amp; reporting can be facilitated by Almac Diagnostic Services Bioinformatics Team if required, at an additional cost.<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p style=\"text-align: center;\"><span style=\"font-family: 'trebuchet ms', geneva; font-weight: bold;\"><a style=\"color: #ffffff; background: #00b0f0; text-decoration: none; border: 2px solid #00b0f0; border-radius: 4px; padding: 8px 14px; font-size: 18px;\" href=\"https:\/\/www.almacgroup.com\/diagnostics\/global-laboratories\/platforms-technologies\/dna-sequencing-solutions\/portfolio-overview-whole-genome-methylation-sequencing\/\" rel=\" noopener\">Find out more<\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item4\" class=\"c-accordion__item u-c-mid-grey accordion-4\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">Whole Exome Sequencing (WES) Services<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p><strong>The Platform<\/strong>: <strong>Almac optimised solution for comprehensive Whole Exome Sequencing (WES)<\/strong> from <strong>multiple sample types<\/strong>, including more challenging Formalin Fixed Paraffin Embedded <strong>(FFPE) material<\/strong>. The platform covers 99.7% of coding exons with readily interpretable raw sequencing data for use in biomarker discovery and retrospective clinical investigation.<\/p>\n<p><strong><span style=\"color: #00b0f0;\">Features &amp; Benefits:<\/span><\/strong><\/p>\n<ul>\n<li>A <strong>comprehensive variant detection platform<\/strong>, covering 213,994 coding exons<\/li>\n<li>QC <strong>guarantee of 100X mean target coverage<\/strong> across sample cohort ensured comprehensive downstream analysis and data interpretation<\/li>\n<li><strong>Machine-learning based bait design<\/strong> of SureSelect Human All Exon V7 maximises coverage with minimal sequencing<\/li>\n<li><strong>Interactive QC report<\/strong> enables rapid and comprehensive sample quality interrogation across cohort<\/li>\n<li>Raw sequence data delivered in FASTQ format and <strong>compatible with the majority of bioinformatics pipelines<\/strong><\/li>\n<\/ul>\n<div class=\"c-diag-table-wrap\">\n<table>\n<tbody>\n<tr>\n<th style=\"background-color: #00b0f0;\"><strong>Metric<\/strong><\/th>\n<th style=\"background-color: #00b0f0;\"><strong>WES Solution<\/strong><\/th>\n<\/tr>\n<tr>\n<td>Chemistry<\/td>\n<td>Agilent Human All Exon V7<\/td>\n<\/tr>\n<tr>\n<td>Tissue Type<\/td>\n<td>Optimised for FFPE (compatible with other sample types on request)<\/td>\n<\/tr>\n<tr>\n<td>Recommended Tissue Requirements<\/td>\n<td>For FFPE, tissue should be macrodissected<br \/>\n10 x 5 \u00b5m FFPE sections with a tissue area &gt;1cm<sup>2<\/sup> and high tumour content &gt;10% viable cells<br \/>\nSpecific guidelines will be provided on a per-project basis<\/td>\n<\/tr>\n<tr>\n<td>Recommended DNA Input<\/td>\n<td>Recommended Minimum 100 ng from FF<br \/>\nRecommended Minimum 100 ng of amplifiable DNA from FFPE<\/td>\n<\/tr>\n<tr>\n<td>Standard Sequencing Specification<\/td>\n<td>On average 100X coverage<br \/>\nOther Sequencing specifications available on request<\/td>\n<\/tr>\n<tr>\n<td>Deliverables<\/td>\n<td>FASTQ, VCF and interactive QC Report as standard. BAM available files on request<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<p style=\"text-align: center;\"><span style=\"font-family: 'trebuchet ms', geneva; font-weight: bold;\"><a style=\"color: #ffffff; background: #00b0f0; text-decoration: none; border: 2px solid #00b0f0; border-radius: 4px; padding: 8px 14px; font-size: 18px;\" href=\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/whole-exome-sequencing\/\" rel=\" noopener\">Find out more<\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item5\" class=\"c-accordion__item u-c-mid-grey accordion-5\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">PGDx elio\u2122 tissue complete<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p><strong><span style=\"color: #00b0f0;\">PGDx elio\u2122 tissue complete<\/span><\/strong><\/p>\n<p><strong>The Platform<\/strong>:\u00a0 The Personal Genome Diagnostics PGDx elio\u2122 tissue complete panel is a comprehensive pan-cancer <em>in vitro<\/em> diagnostic <b>NGS-based assay<\/b>\u00a0that identifies key genomic alterations in <b>505 Full coding genes<\/b>. This assay identifies somatic mutations with high accuracy and sensitivity, providing information on single nucleotide variants (SNVs), insertions\/ deletions (indels), amplifications, translocations, and immune-oncology biomarkers microsatellite instability (MSI) and tumour mutation burden (TMB) in accordance with NCCN guidelines. The automated and robust bioinformatics pipeline ensures consistent, high quality comprehensive results to support critical treatment decisions and cancer care pathways.<\/p>\n<p><strong><span style=\"color: #00b0f0;\">Features &amp; Benefits:<\/span><\/strong><\/p>\n<ul>\n<li>Identifies key genomic alterations in 500+ genes including key immune-oncology biomarkers microsatellite instability (MSI) and tumour mutation burden (TMB).<\/li>\n<li>Utilises a robust automated Bioinformatics pipeline to offer fast, reliable, and comprehensive results.<\/li>\n<li>Identifies potential therapy targets from a single sample to help inform critical treatment decisions.<\/li>\n<\/ul>\n<p><b>* The technical specification table for the PGDx elio\u2122 tissue complete panel is as per the PGDx website and guidelines. For further information visit: <a href=\"https:\/\/www.personalgenome.com\/products\">https:\/\/www.personalgenome.com\/products<\/a><\/b><\/p>\n<div class=\"c-diag-table-wrap\">\n<table class=\"u-table\">\n<tbody>\n<tr>\n<th style=\"background-color: #00b0f0;\">Metric<\/th>\n<th style=\"background-color: #00b0f0;\">PGDx elio\u2122 Solution<\/th>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Chemistry<\/td>\n<td style=\"width: 303px;\">PGDx elio\u2122 tissue complete<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">System<\/td>\n<td style=\"width: 303px;\">Illumina NextSeq<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Genes<\/td>\n<td style=\"width: 303px;\">505 Full Coding Genes<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">DNA input requirement<\/td>\n<td style=\"width: 303px;\">50-100ng<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sequencing coverage<\/td>\n<td style=\"width: 303px;\">2,500x<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Total assay turnaround time<\/td>\n<td style=\"width: 303px;\">For batch retrospective testing \u2013 turnaround time agreed on a per project basis<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Variants<\/td>\n<td style=\"width: 303px;\">SNVs, indels, Amplifications, Translocations, MSI, TMB<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Data Analysis<\/td>\n<td style=\"width: 303px;\">Automated Bioinformatics pipeline<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item6\" class=\"c-accordion__item u-c-mid-grey accordion-6\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">TruSight\u2122 Tumor 170 Clinical Trial Assay<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p><strong><span style=\"color: #00b0f0;\">Almac TruSight\u2122 Tumor 170 Clinical Trial Assay<\/span><\/strong><\/p>\n<p><strong>The Platform<\/strong>:\u00a0 Almac has validated the Illumina TST-170 cancer mutation panel for prospective clinical trial use, within Europe and the US. The TST-170 panel targets <strong>DNA and RNA variants<\/strong> for assessment of 170 genes including <strong>55 genes for fusions and splice variants, 148 for SNVs and Indels<\/strong> and 59 genes for CNV (CNV &#8211; Illumina RUO Assay Only).<\/p>\n<p><strong><span style=\"color: #00b0f0;\">Features &amp; Benefits:<\/span><\/strong><\/p>\n<ul>\n<li><strong>Pan-cancer content<\/strong> aligned with key guidelines and clinical trials<\/li>\n<li><strong>Analytically validated<\/strong> for use in prospective clinical trials<\/li>\n<li><strong>High levels of accuracy and precision from FFPE<\/strong> suitable for clinical trial use<\/li>\n<li><strong>Bespoke Almac bioinformatics pipeline<\/strong>s providing enhanced variant call reproducibility, accuracy and data quality control (QC)<\/li>\n<li><strong>A solution that can be kit-able in future<\/strong> to <strong>support multiple CDx<\/strong><\/li>\n<\/ul>\n<div class=\"c-diag-table-wrap\">\n<table>\n<tbody>\n<tr>\n<th style=\"background-color: #00b0f0;\"><strong>Metric<\/strong><\/th>\n<th style=\"background-color: #00b0f0;\"><strong>Almac TST-170 Solution<\/strong><\/th>\n<\/tr>\n<tr>\n<td>Chemistry<\/td>\n<td>Illumina TruSight\u2122 Tumor 170<\/td>\n<\/tr>\n<tr>\n<td>Tissue Type<\/td>\n<td>Validated for FFPE solid tumour tissue<br \/>\n(compatible with other sample types on request for RUO testing)<\/td>\n<\/tr>\n<tr>\n<td>Recommended Tissue Requirements<\/td>\n<td>1 mm<sup>3\u00a0 <\/sup>Tissue \u221e (If FFPE, tissue should be macrodissected)<br \/>\nSpecific guidelines provided on a per-project basis<\/td>\n<\/tr>\n<tr>\n<td>Recommended Input<\/td>\n<td>120 ng DNA<br \/>\n<span style=\"font-family: inherit; font-size: inherit;\">85 ng RNA*<\/span><\/td>\n<\/tr>\n<tr>\n<td>Standard Sequencing Specification<\/td>\n<td>Minimum coverage of 95% of reportable range \u2265259X<\/td>\n<\/tr>\n<tr>\n<td>Deliverables<\/td>\n<td>FASTQ, VCF, QC Report as standard with Customised Reporting. BAM files available on request<\/td>\n<\/tr>\n<tr>\n<td>Estimated TAT<\/td>\n<td>Approx. 9 days \u00a7 for prospective testing<br \/>\n(From sample receipt, inclusive of pathology review)For RUO testing, timelines advised on a per-project basis<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h6><em>*Ability of TST-170 to analyse RNA allows for detection of expressed fusion genes resulting from both chromosomal abnormalities and posttranscriptional events and thus detects gene fusions that DNA sequencing panels would not recognize<\/em><\/h6>\n<h6><em>\u221e Variable across tissue type; Melanoma would require more tissue; Tissue fixation has greatest influence upon sample QC and assay performance<\/em><\/h6>\n<h6><em>\u00a7 From sample receipt, inclusive of pathology review<\/em><\/h6>\n<p>&nbsp;<\/p>\n<p style=\"text-align: center;\"><span style=\"font-family: 'trebuchet ms', geneva; font-weight: bold;\"><a style=\"color: #ffffff; background: #00b0f0; text-decoration: none; border: 2px solid #00b0f0; border-radius: 4px; padding: 8px 14px; font-size: 18px;\" href=\"\/diagnostics\/trusighttumor170\/\" rel=\" noopener\">Find out more<\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item7\" class=\"c-accordion__item u-c-mid-grey accordion-7\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">TP53 Clinical Trial Assay<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p><strong><span style=\"color: #00b0f0;\">Almac TP53 Clinical Trial Assay<\/span><\/strong><\/p>\n<p><strong>The Platform<\/strong>: A <strong>bespoke single gene assay targeting the TP53 tumour suppressor gene<\/strong>. This assay is intended to <strong>detect genomic germline and somatic DNA aberrations<\/strong> (SNVs and indels) enabling determination of molecular eligibility to facilitate clinical trial enrolment.<\/p>\n<p><strong><span style=\"color: #00b0f0;\">Features &amp; Benefits:<\/span><\/strong><\/p>\n<ul>\n<li><strong>Comprehensive coverage<\/strong> of the full coding sequence<\/li>\n<li><strong>Dual amplicon workflow<\/strong> and<strong> individual base QC <\/strong>ensure high-confidence \u2018Mutation Detected\u2019 &amp; \u2018Not Detected\u2019 status<\/li>\n<li><strong>High levels of accuracy and precision<\/strong> from FFPE suitable for clinical trial use<\/li>\n<li>Rapid turnaround time with powerful reporting and interpretation services<\/li>\n<\/ul>\n<div class=\"c-diag-table-wrap\">\n<table>\n<tbody>\n<tr>\n<th style=\"background-color: #00b0f0;\"><strong>Metric<\/strong><\/th>\n<th style=\"background-color: #00b0f0;\"><strong>\u00a0Almac TP53 Solution<\/strong><\/th>\n<\/tr>\n<tr>\n<td>Chemistry<\/td>\n<td>Illumina TruSeq\u2122 Custom Amplicon Dx<\/td>\n<\/tr>\n<tr>\n<td>Tissue Type<\/td>\n<td>Validated for FFPE solid tumour tissue<br \/>\n(compatible with other sample types on request for RUO testing)<\/td>\n<\/tr>\n<tr>\n<td>Recommended Tissue Requirements<\/td>\n<td>1 mm<sup>3\u00a0 <\/sup>Tumor Tissue (macrodissected)<br \/>\n10% viable tumour cells within marked tumour area<br \/>\nSpecific guidelines will be provided on a per-project basis<\/td>\n<\/tr>\n<tr>\n<td>Recommended Input<\/td>\n<td>Input for FFPE is determined based on sample quality from qPCR amplifiability assessment and comparison to high-quality genomic DNA control<br \/>\n100 ng input for RUO testing of FF tissue, blood, BMA etc<\/td>\n<\/tr>\n<tr>\n<td>Standard Sequencing Specification<\/td>\n<td>Minimum coverage of 99% of reportable range \u2265 1000X<\/td>\n<\/tr>\n<tr>\n<td>Deliverables<\/td>\n<td>FASTQ, VCF, QC Report as standard with Customised Reporting. BAM files available on request<\/td>\n<\/tr>\n<tr>\n<td>Estimated TAT<\/td>\n<td>Approx. 7 days \u00a7 for prospective testing<br \/>\n(From sample receipt, inclusive of pathology review)<br \/>\nFor RUO testing, timelines advised on a per-project basis<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<h6><em>\u00a7 From sample receipt, inclusive of pathology review<\/em><\/h6>\n<p style=\"text-align: center;\"><span style=\"font-family: 'trebuchet ms', geneva; font-weight: bold;\"><a style=\"color: #ffffff; background: #00b0f0; text-decoration: none; border: 2px solid #00b0f0; border-radius: 4px; padding: 8px 14px; font-size: 18px;\" href=\"\/diagnostics\/portfolio-overview\/tp53-clinical-trial-assay\/\" rel=\" noopener\">Find out more<\/a><\/span><\/p>\n<p>&nbsp;<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item8\" class=\"c-accordion__item u-c-mid-grey accordion-8\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">Custom DNA Sequencing Solutions<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p><strong><span style=\"color: #00b0f0;\">Custom DNA Sequencing Solutions<\/span><\/strong><\/p>\n<p>We offer the development of custom RUO DNA sequencing solutions for retrospective use tailored to clients exact requirements.<\/p>\n<p>When a biomarker assay is required for trial enrichment, or a patient treatment decision will be made based on the result, assays must be run under CLIA \/ GLP. Not all biomarker assays that take place in the clinical trial setting will result in patient treatment decisions; those that are <strong><a href=\"\/diagnostics\/clinical-trial-solutions\/pharmacodynamic-biomarker-testing\/?utm_campaign=DX_EDM_PDBiomarkerTesting_Feb2020&amp;utm_source=DX_EDM_PDBiomarkerTesting_Feb2020\">pharmacodynamic (PD) biomarkers<\/a><\/strong> or assays for research use only purposes (RUO) do not require the same level of validation and are typically run retrospectively in batches as the trial progresses.<\/p>\n<p>Although the validation requirements are less stringent, we develop and process these assays under the same quality management system and with the same processes and protocols for robust delivery.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/div> <!-- \/c-tabs -->\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div> <!-- \/o-grid -->\n\t<\/div> <!-- \/o-wrapper -->\n<\/section>\n\n\n\n<div style=\"height:29px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3>Almac Additional Benefits for DNA Sequencing Solutions<\/h3>\n<p><strong><span>Flexible Extraction Protocols:<\/span><\/strong> Almac offer both high-quality <strong>single DNA extractions and a dual RNA \/ DNA extraction protocol<\/strong> for our DNA-Sequencing solutions. Dual extraction facilitates simultaneous generation of <a href=\"\/diagnostics\/rna-sequencing-solutions\/\"><strong>RN<\/strong><strong>A-Seq<\/strong><\/a> data and DNA-Seq data from a single sample, <strong>conserving valuable sample material<\/strong>.<\/p>\n<p><strong><span>Customisable Analysis &amp; Reporting:<\/span><\/strong> Data analysis and reporting is performed using the latest DRAGEN suite of secondary analysis tools and\/or <strong>Almac customised<\/strong> <a href=\"\/diagnostics\/supporting-services\/bioinformatics-biostatistics-software-development\/\"><strong><u>bioinformatics<\/u><\/strong><\/a> <strong>pipelines<\/strong> hosted on the Illumina Connected Analytics (ICA) platform. ICA is a <strong>cloud-based NGS solution<\/strong> which enables full integration with Illumina sequencing instruments, whilst ensuring scalability and security of project data. A significant benefit of utilising ICA within this offering is the <strong>flexibility of workflow optimisation<\/strong> and the <strong>ability to customise bespoke pipelines<\/strong>.\n<br>\n<br>\n<h3><span>DNA-Sequencing Resources<\/span><\/h3>\n<p>To view additional resources such as whitepapers, technical factsheets, webinars and other information, <a href=\"#relatedResourcesScroll\">click here.<\/a><\/p>\n<br>\n<br>\n<h3><span>Contact Us<\/span><\/h3>\n<p>Interested in partnering with Almac on your biomarker project using our DNA Sequencing Solutions? Get in touch below:&nbsp;<\/p>\n\n\n\n\n\n\n\n<style>\r\n.c-hero.c-hero--diagnostics:before {\r\n  background: linear-gradient(to right,#00b0f0 0%,rgba(0,176,240,0) 50%,rgba(255,255,255,0) 100%);\r\n}\r\n.dx-bio .c-careers__accordions .c-accordion__item:after {\r\n  content: '';\r\n}\r\n.c-table__bg table td {\r\n  background-color: white;\r\n  color: #798085;\r\n  border: 2px solid #798085;\r\n}\r\n.c-diag-table-wrap th {\r\n  border: 2px solid #798085;\r\n}\r\n<\/style>\n\n\n\n<div style=\"height:56px\" aria-hidden=\"true\" id=\"relatedResourcesScroll\" class=\"wp-block-spacer\"><\/div>\n\n\n\t<article class=\"o-grid o-grid--full\">\n\n\t\t<div class=\"o-grid__item u-width-full u-m-t6 u-m-t4@m u-m-b4\">\n\t\t\t<h2 class=\"u-normal u-a-center\">Related Resources<\/h2>\n\t\t<\/div>\n\n\t\t<div class=\"u-flex u-flex-justify-center u-flex-wrap u-width-full c-news-panels__slider js-news-panels\">\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2023\/06\/Almac-Dx-Whole-Genome-Sequencing-Factsheet-Website-FINAL-FINAL.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">WGS Technical Specification<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2024\/01\/ALMAC-Dx-WGMS-Brochure-FINAL-Online-Jan-2024.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">WGMS Technical Specification<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.illumina.com\/products\/by-type\/clinical-research-products\/trusight-oncology-500.html\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TSO-500 Technical Specification<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/06\/Almac-Dx-WES-Factsheet-Updated-June-2025.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">WES Technical Specification<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.illumina.com\/products\/by-type\/clinical-research-products\/trusight-tumor-170.html\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TST-170 Technical Specification (RUO)<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/wp-content\/uploads\/2019\/01\/21358-ALMAC-TST-170-Validation-Report-D1.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TST-170 Performance Specification<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/wp-content\/uploads\/2020\/03\/ALMAC-Diagnostics-TST170-Assay-Sheet-March-2020-V2.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Publication<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TST-170 Technical Specification (IUO)<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/news\/tst170-validation\/\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Article<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TST-170 PR<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/diagnostics\/diagnostic-resource\/almac-validate-illumina-trusight-tumor-170-assay\/\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Webinar<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TST-170 Webinar<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/wp-content\/uploads\/2019\/11\/Almac-Dx-TP53-Assay-Factsheet.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TP53 Technical Specification<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"\/wp-content\/uploads\/2019\/11\/Almac-Dx-TP53-Assay-Performance-Specification.pdf\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/04\/diagnostics-menu-panels.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-white\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TP53 Performance Specification<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t<\/div>\n\t<\/article>\n\n\n<!-- <article id=\"related\">\n\t<div class=\"o-grid\">\n\t\t\t\t<div class=\"o-grid__item u-width-full u-a-center\">\n\t\t\t\t\t\t\t<h3 class=\"u-normal u-m-b4\">Related Resources<\/h3>\n\t\t\t\t\t<\/div>\n\t\n\t\t<div class=\"u-flex u-flex-justify-center u-flex-wrap u-width-full c-resources__slider js-resources-panels\">\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2023\/06\/Almac-Dx-Whole-Genome-Sequencing-Factsheet-Website-FINAL-FINAL.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">WGS Technical Specification<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2024\/01\/ALMAC-Dx-WGMS-Brochure-FINAL-Online-Jan-2024.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">WGMS Technical Specification<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.illumina.com\/products\/by-type\/clinical-research-products\/trusight-oncology-500.html\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TSO-500 Technical Specification<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/06\/Almac-Dx-WES-Factsheet-Updated-June-2025.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">WES Technical Specification<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.illumina.com\/products\/by-type\/clinical-research-products\/trusight-tumor-170.html\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TST-170 Technical Specification (RUO)<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"\/wp-content\/uploads\/2019\/01\/21358-ALMAC-TST-170-Validation-Report-D1.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TST-170 Performance Specification<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"\/wp-content\/uploads\/2020\/03\/ALMAC-Diagnostics-TST170-Assay-Sheet-March-2020-V2.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Publication<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TST-170 Technical Specification (IUO)<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"\/news\/tst170-validation\/\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Article<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TST-170 PR<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"\/diagnostics\/diagnostic-resource\/almac-validate-illumina-trusight-tumor-170-assay\/\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Webinar<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TST-170 Webinar<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"\/wp-content\/uploads\/2019\/11\/Almac-Dx-TP53-Assay-Factsheet.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Almac-Diagnostics-DNA-panel-solution.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TP53 Technical Specification<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-1\/3 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"\/wp-content\/uploads\/2019\/11\/Almac-Dx-TP53-Assay-Performance-Specification.pdf\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/04\/diagnostics-menu-panels.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Sheet<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TP53 Performance Specification<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/article> -->\n\n\n\n<div style=\"height:40px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Background Information Almac Diagnostic Services has implemented a range of comprehensive next-generation sequencing (NGS) solutions including large panels, mid-size panels and bespoke single gene assays.&nbsp; These multiple solutions are analysed using the Illumina MiSeq, NextSeq500, NextSeq550, NovaSeq6000 and NovaSeq X Plus sequencing platforms.&nbsp; Our DNA-Sequencing solutions support novel biomarker discovery through to prospective clinical trial [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":43,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-page-wrapper.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1229","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>DNA-Sequencing Solutions - Diagnostic Services<\/title>\n<meta name=\"description\" content=\"A range of comprehensive next-generation sequencing (NGS) solutions including large panels, mid-size panels and bespoke single gene assays.\u00a0Our DNA-Sequencing solutions support novel biomarker discovery through to prospective clinical trial use, supported by Almac innovative proprietary\u00a0bioinformatics solutions.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/diagnostics\/global-laboratories\/platforms-technologies\/dna-sequencing-solutions\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"DNA-Sequencing Solutions\" \/>\n<meta property=\"og:description\" content=\"A range of comprehensive next-generation sequencing (NGS) solutions including large panels, mid-size panels and bespoke single gene assays.\u00a0Our DNA-Sequencing solutions support 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