{"id":2274,"date":"2020-12-09T14:04:38","date_gmt":"2020-12-09T14:04:38","guid":{"rendered":"https:\/\/www.almacgroup.com\/diagnostics\/?page_id=2274"},"modified":"2025-05-20T15:06:19","modified_gmt":"2025-05-20T14:06:19","slug":"liquid-biopsy-solutions","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/diagnostics\/liquid-biopsy-solutions\/","title":{"rendered":"Liquid Biopsy Solutions"},"content":{"rendered":"\n<p>Almac Diagnostic Services offer a range of comprehensive <strong>next-generation sequencing (NGS) Liquid Biopsy solutions, including large and mid-size panels<\/strong>, analysed using the Illumina NovaSeq6000 and NextSeq 500\/550 sequencing platforms.<\/p>\n\n\n\n<p>Our Liquid Biopsy solutions offer BioPharma clients a non-invasive approach, providing a rapid and precise <strong>translational research &amp; <a href=\"https:\/\/www.almacgroup.com\/diagnostics\/clinical-trial-solutions\/biomarker-discovery\/\">biomarker discovery<\/a><\/strong> tool for early diagnosis screening, drug resistance and tumour heterogeneity in real-time. <\/p>\n\n\n\n<p>These include:<\/p>\n\n\n\n<figure class=\"wp-block-image size-large u-hidden@m\"><a href=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW.png\"><img decoding=\"async\" width=\"1024\" height=\"512\" data-src=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-1024x512.png\" alt=\"\" class=\"wp-image-5963 lazyload\" data-srcset=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-1024x512.png 1024w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-300x150.png 300w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-768x384.png 768w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-1536x768.png 1536w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-1120x560.png 1120w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-480x240.png 480w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW.png 1750w\" data-sizes=\"(max-width: 1024px) 100vw, 1024px\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 1024px; --smush-placeholder-aspect-ratio: 1024\/512;\" \/><noscript><img decoding=\"async\" width=\"1024\" height=\"512\" src=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-1024x512.png\" alt=\"\" class=\"wp-image-5963\" srcset=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-1024x512.png 1024w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-300x150.png 300w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-768x384.png 768w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-1536x768.png 1536w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-1120x560.png 1120w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW-480x240.png 480w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW.png 1750w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/noscript><\/a><\/figure>\n\n\n\n<figure class=\"wp-block-image size-large u-hidden u-block@m\"><a href=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW.png\"><img decoding=\"async\" width=\"1024\" height=\"647\" data-src=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-1024x647.png\" alt=\"\" class=\"wp-image-5964 lazyload\" data-srcset=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-1024x647.png 1024w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-300x189.png 300w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-768x485.png 768w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-1536x970.png 1536w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-887x560.png 887w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-480x303.png 480w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW.png 2000w\" data-sizes=\"(max-width: 1024px) 100vw, 1024px\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 1024px; --smush-placeholder-aspect-ratio: 1024\/647;\" \/><noscript><img decoding=\"async\" width=\"1024\" height=\"647\" src=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-1024x647.png\" alt=\"\" class=\"wp-image-5964\" srcset=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-1024x647.png 1024w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-300x189.png 300w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-768x485.png 768w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-1536x970.png 1536w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-887x560.png 887w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW-480x303.png 480w, https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_MOBILE_FINAL_AW.png 2000w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/noscript><\/a><\/figure>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"wp-block-heading\" id=\"h-to-find-out-more-information-on-each-almac-solution-click-the-appropriate-drop-down-below\"><strong>To find out more information on each Almac solution, click the appropriate drop-down below:<\/strong><\/h3>\n\n\n<!-- Accordions -->\n<section class=\"u-bg-light-grey u-p-y4 t-theme-component-overwrite\" id=\"accordionBlock\">\n\t<div class=\"o-wrapper\">\n\t\t<div class=\"o-grid o-grid--center\">\n\t\t\t<div class=\"o-grid__item u-width-full u-align-center u-align-left@m\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t<div class=\"u-m-t2\">\n\t\t\t\t\t<div class=\"c-accordion js-accordion\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item1\" class=\"c-accordion__item u-c-mid-grey accordion-1\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">TruSight Oncology 500 ctDNA<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 style=\"color: #c52d2c;\">TruSight Oncology 500 ctDNA (Research Use Only)<\/h4>\n<p><b>The Platform:<\/b> The Illumina TruSight Oncology 500 circulating tumour DNA (ctDNA) assay is an <b>NGS-based assay<\/b> that enables <b>comprehensive genomic profiling to assess multiple variant types in 523 cancer-related genes from cell-free DNA (cfDNA)<\/b>. This assay features the same DNA content as the TruSight Oncology 500 solid tumor assay for detection of single nucleotide variants (SNVs), indels, copy number variants (CNVs), DNA fusions, tumour mutational burden (TMB), and microsatellite instability (MSI) from plasma samples.<\/p>\n<p>In addition, the <b>DRAGEN Bio-IT Platform<\/b> offers speed and accuracy to detect variants through its ultra-rapid variant calling algorithm.<\/p>\n<p><img decoding=\"async\" data-src=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/dragenv3.png\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" class=\"lazyload\" style=\"--smush-placeholder-width: 130px; --smush-placeholder-aspect-ratio: 130\/66;\" \/><noscript><img decoding=\"async\" src=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/dragenv3.png\" \/><\/noscript><\/p>\n<h5 style=\"color: #c52d2c;\">Benefits<\/h5>\n<ul>\n<li>Enables comprehensive tumour cell profiling when tissue biopsy is not an option.<\/li>\n<li>Targets multiple biomarkers and somatic variant types in a single assay with limited sample input requirements.<\/li>\n<li>Allows monitoring of disease progression, response to treatment and acquired resistance.<\/li>\n<\/ul>\n<h5 style=\"color: #c52d2c;\">Features<\/h5>\n<ul>\n<li>Coverage of current and emerging biomarkers including comprehensive coverage of key cancer-associated genes across multiple tumour types.<\/li>\n<li>Immuno-oncology relevant biomarker readouts including blood TMB (bTMB) and blood MSI (bMSI).<\/li>\n<li>Unique molecular barcode (UMI) technology, high raw coverage enabled by the NovaSeq 6000 system, and <em>in silico<\/em> error correction models improve variant calling and reduce artefacts.<\/li>\n<li>Ultra-rapid variant calling powered and accelerated by DRAGEN Bio-IT Platform.<\/li>\n<li>Robust variant calling performance demonstrated for low frequency (&lt;0.5%) variants.<\/li>\n<li>Hybrid capture enrichment library preparation coupled with comprehensive content enables novel variant and rearrangement detection without a <em>priori<\/em> knowledge.<\/li>\n<li>Upstream cfDNA QC enables assessment of gDNA contamination in sample prior to library preparation and sequencing, enabling contextualisation of observed results.<\/li>\n<li>Comprehensive variant annotation allows effective triage of clinically actionable variants.<\/li>\n<\/ul>\n<div class=\"c-diag-table-wrap\">\n<table class=\"u-table\">\n<tbody>\n<tr>\n<th style=\"background-color: #c52d2c;\">Metric<\/th>\n<th style=\"background-color: #c52d2c;\">TSO-500 ctDNA Solution<\/th>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Chemistry<\/td>\n<td style=\"width: 303px;\">Illumina TruSight Oncology 500 ctDNA<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">System<\/td>\n<td style=\"width: 303px;\">NovaSeq 6000\u2122 System<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Genes<\/td>\n<td style=\"width: 303px;\">523 genes. See Illumina Website under \u2018Product Literature\u2019 for <a class=\"u-color-blue\" href=\"https:\/\/www.illumina.com\/products\/by-type\/clinical-research-products\/trusight-oncology-500-ctdna.html\">(Full Gene List)<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Panel Size<\/td>\n<td style=\"width: 303px;\">1.94 Mb DNA<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sample type<\/td>\n<td style=\"width: 303px;\">Plasma<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">DNA input requirement<\/td>\n<td style=\"width: 303px;\">30ng<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Standard Sequencing Specification<\/td>\n<td style=\"width: 303px;\">Median Exon Coverage \u22651300X<\/p>\n<p>\u226580% of target exons covered at \u22651000X<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Total assay turnaround time<\/td>\n<td style=\"width: 303px;\">For batch retrospective testing &#8211; turnaround time agreed on a per project basis<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Run time<\/td>\n<td style=\"width: 303px;\">44 hrs Sequencing run time (S4 flowcell)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sample throughput<\/td>\n<td style=\"width: 303px;\">24 Libraries per run (S4 flowcell)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Variants<\/td>\n<td style=\"width: 303px;\">SNVs and indels, DNA fusions, CNVs, MSI, TMB<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Limit of detection (VAF)<\/td>\n<td style=\"width: 303px;\">0.5% VAF for small variants (as per Illumina\u2019s manufacturing guidelines)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Data Analysis<\/td>\n<td style=\"width: 303px;\">DRAGEN Server pipeline<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Deliverables \/ Output files<\/td>\n<td style=\"width: 303px;\">BCL<br \/>\nFASTQ<br \/>\ngVCF<br \/>\nAnnotated Small Variant Report<br \/>\nCopy Number Variants Report<br \/>\nFusion Report<br \/>\nCombined Variant Report<br \/>\nMetrics Report<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item2\" class=\"c-accordion__item u-c-mid-grey accordion-2\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">LIQUIDPlex \u2122<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 style=\"color: #c52d2c;\">Archer LIQUIDPlex \u2122 (Research Use only)<\/h4>\n<p><b>The Platform:<\/b> The Archer LiquidPlex panel is a <b>customisable NGS-based assay<\/b> which allows <b>profiling of cell-free DNA (cfDNA) samples to assess small variants across 28 key genes of interest across a variety of cancer types<\/b> (additional genes can be added on request.<\/p>\n<p>The assay enables the <b>calling of small variants at low allelic fractions through the use of unique molecular barcodes and an Archer Analysis bioinformatics pipeline<\/b> applying <b>Almac-optimised parameters<\/b>.<\/p>\n<p><img decoding=\"async\" data-src=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/archer.png\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" class=\"lazyload\" style=\"--smush-placeholder-width: 132px; --smush-placeholder-aspect-ratio: 132\/50;\" \/><noscript><img decoding=\"async\" src=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/archer.png\" \/><\/noscript><\/p>\n<p>This results in <b>highly sensitive variant calling, enabling somatic variant detection in this sample type, without sacrificing specificity<\/b>. The smaller panel size and library preparation methodology allows for a <b>rapid turnaround from sample acquisition to result<\/b> and, <b>reduces the need for large sequencing read budgets<\/b> by focusing on key oncology driver genes.<\/p>\n<h4 style=\"color: #c52d2c;\">Features &amp; Benefits<\/h4>\n<h5 style=\"color: #c52d2c;\">Benefits<\/h5>\n<ul>\n<li>Low input to library preparation amenable to cfDNA yields obtainable from plasma samples.<\/li>\n<li>Anchored multiplex PCR based library preparation method enables faster turnaround times from cfDNA sample to result.<\/li>\n<li>Smaller panel size reduces sequencing read budget requirements.<\/li>\n<li>Cloud based analysis platform allows scale up for large sample cohorts without impacting turnaround times.<\/li>\n<\/ul>\n<h5 style=\"color: #c52d2c;\">Features<\/h5>\n<ul>\n<li>Archer Analysis variant calling pipeline applying Almac-optimised parameters ensures highly sensitive and specific variant calling.<\/li>\n<li>Unique molecular barcodes enable consensus read generation to allow variant calling at allele frequencies below short read sequencer error rates.<\/li>\n<li>Customisable gene content to suit your analysis application.<\/li>\n<li>Filtering of germline polymorphisms enables a focus on key mutations of interest and discernment of underlying biology.<\/li>\n<li>Custom variant annotation available on request.<\/li>\n<\/ul>\n<div class=\"c-diag-table-wrap\">\n<table class=\"u-table\">\n<tbody>\n<tr>\n<th style=\"background-color: #c52d2c;\">Metric<\/th>\n<th style=\"background-color: #c52d2c;\">LIQUIDPlex\u2122 Solution<\/th>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Chemistry<\/td>\n<td style=\"width: 303px;\">Archer LIQUIDPlex\u2122<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">System<\/td>\n<td style=\"width: 303px;\">Illumina NextSeq 550\/500<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Genes<\/td>\n<td style=\"width: 303px;\">Customisable<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Panel Size<\/td>\n<td style=\"width: 303px;\">28 Key Oncology Genes (Additional content can be added). See Archer Website for <a class=\"u-color-blue\" href=\"https:\/\/archerdx.com\/liquidplex\/\">(More Information)<\/a><\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sample type<\/td>\n<td style=\"width: 303px;\">Plasma\/ cfDNA<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">DNA input requirement<\/td>\n<td style=\"width: 303px;\">50ng minimum input recommended<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Standard Sequencing Specification<\/td>\n<td style=\"width: 303px;\">&gt;5 Million 2x151bp reads per sample. Custom read budgets for more sensitive applications are also available<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Total assay turnaround time<\/td>\n<td style=\"width: 303px;\">For batch retrospective testing &#8211; turnaround time agreed on a per project basis<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sequencing Run time<\/td>\n<td style=\"width: 303px;\">29 Hours per run<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sample throughput<\/td>\n<td style=\"width: 303px;\">Variable depending on flowcell type and required read budget<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Variants<\/td>\n<td style=\"width: 303px;\">Key hotspot mutations and de novo mutations covered across 28 genes<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Minimum Theoretical Detectable Variant allele frequency (VAF)<\/td>\n<td style=\"width: 303px;\">0.1%<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Data Analysis<\/td>\n<td style=\"width: 303px;\">Archer Analysis ctDNA variant calling pipeline hosted on Archer Analysis Unlimited cloud platform (with Almac-optimised parameters)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Deliverables \/ Output files<\/td>\n<td style=\"width: 303px;\">Raw unfiltered variant calls<br \/>\nFiltered and annotated variant calls files (custom filtering and\/or annotation available on request)<br \/>\nBAM Files<br \/>\nFASTQ Files<br \/>\nAlignment Statistics QC Reports<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item3\" class=\"c-accordion__item u-c-mid-grey accordion-3\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">PGDx elio\u2122 plasma complete<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 style=\"color: #c52d2c;\">PGDx elio\u2122 plasma complete<\/h4>\n<p><b>The Platform:<\/b> The Personal Genome Diagnostics PGDx elio\u2122 plasma complete panel is a comprehensive multi-gene pan-cancer\u00a0<b>NGS-based assay<\/b>\u00a0that assesses\u00a0<b>521 genes<\/b>\u00a0for Sequence Mutations (SNV and indels), <b>38 genes<\/b> for amplifications, <b>21 genes<\/b> for translocations, as well as key genomic signatures including <b>TMB, MSI and LoH<\/b> in circulating cell-free DNA (cfDNA). This qualitative research use assay enables comprehensive genomic profiling of cfDNA derived from plasma from Streck BCT (or equivalent) or, EDTA tubes, using targeted high throughput, parallel-sequencing technology.<\/p>\n<p>The\u00a0<b>PGDx Elio Analysis platform<\/b>\u00a0performs automated and streamlined analysis of resultant data, enabling high throughput analyses of complex blood based biomarkers.<\/p>\n<h5 style=\"color: #c52d2c;\">Features &amp; Benefits:<\/h5>\n<ul>\n<li>A comprehensive genomic profiling panel that identifies key genomic alterations in 521 pan-solid tumor genes across all variant classes.<br \/>\n25,000 X raw sequencing coverage. &gt;2,000 X deduplicated coverage, error corrected coverage enabling confidence in variant calling<\/li>\n<li>Utilises a robust automated Bioinformatics pipeline offering fast, reliable and comprehensive results, simplifying analysis.<\/li>\n<\/ul>\n<p><b> The technical specification table for the PGDx elio\u2122 plasma complete panel is as per the PGDx website and guidelines. For further information visit:\u00a0<a href=\"https:\/\/www.personalgenome.com\/products\">https:\/\/www.personalgenome.com\/products<\/a> <\/b><\/p>\n<div class=\"c-diag-table-wrap\">\n<table class=\"u-table\">\n<tbody>\n<tr>\n<th style=\"background-color: #c52d2c;\">Metric<\/th>\n<th style=\"background-color: #c52d2c;\">PGDx elio\u2122 Solution<\/th>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Chemistry<\/td>\n<td style=\"width: 303px;\">PGDx elio\u2122 plasma complete<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">System<\/td>\n<td style=\"width: 303px;\">Illumina Novaseq<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Genes<\/td>\n<td style=\"width: 303px;\">521 Pan Solid Tumor Genes<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Panel Size<\/td>\n<td style=\"width: 303px;\">0.24 Mb<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sample type<\/td>\n<td style=\"width: 303px;\">Plasma<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">DNA input requirement<\/td>\n<td style=\"width: 303px;\">25ng<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Standard Sequencing Specification<\/td>\n<td style=\"width: 303px;\">Average Total Coverage: 25,000x<br \/>\nAverage unique coverage (assuming 25ng input): 2\u2019000x<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Read length<\/td>\n<td style=\"width: 303px;\">2 x 140bp<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Total assay turnaround time<\/td>\n<td style=\"width: 303px;\">For batch retrospective testing \u2013 turnaround time agreed on a per project basis<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Variants<\/td>\n<td style=\"width: 303px;\">SNVs and indels, Amplifications, Rearrangements, bTMB, MSI, LoH<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Manufacturer stated Sensitivity (LoD95)<\/td>\n<td style=\"width: 303px;\">Actionable SNV and Indel: 0.40% VAF<br \/>\nNon-actionable SNV and Indel: 1.16% VAF<br \/>\nTranslocations: 0.33% VAF<br \/>\nAmplifications: 1.32-fold<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Data Analysis<\/td>\n<td style=\"width: 303px;\">PGDx Elio Analysis server<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item4\" class=\"c-accordion__item u-c-mid-grey accordion-4\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">PGDx elio\u2122 plasma focus<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<h4 style=\"color: #c52d2c;\">PGDx elio\u2122 plasma focus<\/h4>\n<p><b>The Platform:<\/b> The Personal Genome Diagnostics PGDx elio\u2122 plasma focus panel is a broad multi-gene pan-cancer <b>NGS-based assay<\/b>\u00a0that assesses <b>33 Full coding genes<\/b> for Sequence Mutations in circulating cell-free DNA (cfDNA). This qualitative in vitro diagnostic assay uses targeted high throughput, parallel-sequencing technology to detect single nucleotide variants (SNVs), small insertions\/deletions (indels), amplifications, rearrangements, and microsatellite instability (MSI) from plasma samples.<\/p>\n<h5 style=\"color: #c52d2c;\">Features &amp; Benefits:<\/h5>\n<ul>\n<li>A comprehensive genomic profiling diagnostic panel that identifies key genomic alterations in 30+ genes including key immune-oncology biomarker microsatellite instability (MSI).<\/li>\n<li>Utilises a robust automated Bioinformatics pipeline to offer fast, reliable and comprehensive results.<\/li>\n<li>Faster turnaround time to reliable results, enabling the best and most informed treatment decisions<\/li>\n<\/ul>\n<p><b>* The technical specification table for the PGDx elio\u2122 plasma focus panel is as per the PGDx website and guidelines. For further information visit: <a href=\"https:\/\/www.personalgenome.com\/products\">https:\/\/www.personalgenome.com\/products<\/a><\/b><\/p>\n<div class=\"c-diag-table-wrap\">\n<table class=\"u-table\">\n<tbody>\n<tr>\n<th style=\"background-color: #c52d2c;\">Metric<\/th>\n<th style=\"background-color: #c52d2c;\">PGDx elio\u2122 Solution<\/th>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Chemistry<\/td>\n<td style=\"width: 303px;\">PGDx elio\u2122 plasma focus<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">System<\/td>\n<td style=\"width: 303px;\">Illumina NextSeq<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Genes<\/td>\n<td style=\"width: 303px;\">33 Full Coding Genes<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Panel Size<\/td>\n<td style=\"width: 303px;\">0.24 Mb<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sample type<\/td>\n<td style=\"width: 303px;\">Plasma<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">DNA input requirement<\/td>\n<td style=\"width: 303px;\">25ng<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Standard Sequencing Specification<\/td>\n<td style=\"width: 303px;\">Average Total Coverage 30,000x<br \/>\nAverage Distinct Coverage 2,600x<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Read length<\/td>\n<td style=\"width: 303px;\">2 x 150bp<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Total assay turnaround time<\/td>\n<td style=\"width: 303px;\">For batch retrospective testing \u2013 turnaround time agreed on a per project basis<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Variants<\/td>\n<td style=\"width: 303px;\">SNVs and indels, Amplifications, Rearrangements, MSI<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Sensitivity<\/td>\n<td style=\"width: 303px;\">0.1% (select actionable) 0.5% (all bases)<\/td>\n<\/tr>\n<tr>\n<td style=\"width: 123px;\">Data Analysis<\/td>\n<td style=\"width: 303px;\">PGDx elio\u1d40\u1d39\u00a0Bioinformatics<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/div> <!-- \/c-tabs -->\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div> <!-- \/o-grid -->\n\t<\/div> <!-- \/o-wrapper -->\n<\/section>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<!-- Half image, half text -->\n<section class=\"u-bg-white t-theme-component-overwrite\" id=\"halfMediaTextBlock\">\n    <div class=\"c-half-media-text \">\n        <div class=\"o-wrapper\">\n                                                                                    <article class=\"o-grid download u-bg-white\">\n                                <div class=\"o-grid__item u-width-8\/12 u-width-full@m u-p-r3 u-p-r0@m u-flex u-flex-direction-column u-flex-align-flex-start u-flex-justify-center c-half-media-text__ie-fix\">\n                                                                        <h2 style=\"color: #c52d2c;\">Liquid Biopsy Resources<\/h2>\n<p>View Almac\u2019s TruSightOncology 500 ctDNA factsheet and performance evaluation including key outcomes of running the Illumina panel in our diagnostic laboratory. Click the resource to find out more:<\/p>\n                                                                    <\/div>\n                                <div class=\"o-grid__item u-width-4\/12 u-width-full@m\">\n                                    <div class=\"c-resource__featured c-resource__featured-new u-m-t4@m\">\n                                        <div class=\"u-bg-panel-grey u-p-a2 u-align-center\">\n                                            <img decoding=\"async\" alt=\"Image\" data-src=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/Almac-TruSightOncologyctDNA-factsheet-e1607522069486.png\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" class=\"lazyload\" style=\"--smush-placeholder-width: 509px; --smush-placeholder-aspect-ratio: 509\/708;\"><noscript><img decoding=\"async\" alt=\"Image\" src=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/Almac-TruSightOncologyctDNA-factsheet-e1607522069486.png\"><\/noscript>\n                                        <\/div>\n                                        <section class=\"u-p-t2 u-p-b3 u-p-x3 u-bg-light-grey\">\n                                            <h4><a href=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/Illumina-TruSight-Oncology-500-ctDNA-Technical-Specification-Performance-Evaluation.pdf\" target=\"_blank\">Almac\u2019s TruSight Oncology 500 ctDNA Factsheet<\/a><\/h4>\n                                            <div><a class=\"c-btn c-btn2\" href=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/Illumina-TruSight-Oncology-500-ctDNA-Technical-Specification-Performance-Evaluation.pdf\" target=\"_blank\">Download Resource<\/a><\/div>\n                                        <\/section>\n                                    <\/div>\n                                <\/div>\n                            <\/article>\n                                                                <\/div>\n    <\/div>\n<\/section>\n\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 style=\"color: #c52d2c;\">Contact Us<\/h2>\n<p>Interested in partnering with Almac on your biomarker project using our (RUO) Liquid Biopsy Sequencing Solutions? Get in touch below: <\/p>\n<!-- [if lte IE 8]>\n<script charset=\"utf-8\" type=\"text\/javascript\" src=\"\/\/js.hsforms.net\/forms\/v2-legacy.js\"><\/script>\n<![endif]--><\/p>\n<p><script charset=\"utf-8\" type=\"text\/javascript\" src=\"\/\/js.hsforms.net\/forms\/v2.js\"><\/script> <script>\n  hbspt.forms.create({\n\tportalId: \"742105\",\n\tformId: \"fb28842d-1f6c-4c23-a2df-bf58af6e5c68\"\n});\n<\/script><\/p>\n<h6>*By submitting your information you acknowledge that you have read the privacy statement and you consent to our processing the data in accordance with that privacy statement. We may, from time to time, send you material relevant to your interests. If you change your mind at any time about wishing to receive material from us, you can send an email to info@almacmultisite.web.flint. Every email we send you will also include an unsubscribe link so you can unsubscribe from our marketing list.<\/h6>\n\n\n\n<style>\n.c-hero.c-hero--diagnostics:before {\n  background: linear-gradient(to right,#00b0f0 0%,rgba(0,176,240,0) 50%,rgba(255,255,255,0) 100%);\n}\n.dx-bio .c-careers__accordions .c-accordion__item:after {\n  content: '';\n}\n.c-table__bg table td {\n  background-color: white;\n  color: #798085;\n  border: 2px solid #798085;\n}\n.c-diag-table-wrap th {\n  border: 2px solid #798085;\n}\n<\/style>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\t<article class=\"o-grid o-grid--full\">\n\n\t\t<div class=\"o-grid__item u-width-full u-m-t6 u-m-t4@m u-m-b4\">\n\t\t\t<h2 class=\"u-normal u-a-center\">Related Resources<\/h2>\n\t\t<\/div>\n\n\t\t<div class=\"u-flex u-flex-justify-center u-flex-wrap u-width-full c-news-panels__slider js-news-panels\">\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/diagnostics\/?p=2442&#038;post_type=diagnostic_resource&#038;preview=1&#038;_ppp=c9772050c9\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/dx-box-img.png&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Webinar<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">The Realities of Running Next-Generation Sequencing Liquid Biopsy Panels in Clinical Trials<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#0\">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/Liquid-Biopsy-iStock-Photo-2-e1619687085988.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Technical Publication<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">Technical Specification and Performance Evaluation<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t\t\t<article class=\"u-width-1\/4 u-width-half@l u-width-full@m\">\n\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/news\/trusight-oncology-family-grows-with-liquid-biopsy-and-high-throughput-assay-additions\/ \">\n\t\t\t\t\t\n\t\t\t\t\t\t<div class=\"c-news-panels u-a-center\">\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__img lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/Liquid-Biopsy-iStock-Photo-2-e1619687085988.jpg&#039;)\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-meta\">Article<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\n\t\t\t\t\t\t\t<div class=\"c-news-panels__content u-width-full u-p-x2 u-p-y2 u-bg-\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<p class=\"u-text-18 u-normal\">TSO-500 ctDNA (RUO) PR<\/p>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t<\/div>\n\t<\/article>\n\n\n<!-- <article id=\"related\">\n\t<div class=\"o-grid\">\n\t\t\t\t<div class=\"o-grid__item u-width-full u-a-center\">\n\t\t\t\t\t\t\t<h2 class=\"u-normal u-m-b5\">Related Resources<\/h2>\n\t\t\t\t\t<\/div>\n\t\n\t\t<div class=\"u-flex u-flex-justify-center u-flex-wrap u-width-full c-resources__slider js-resources-panels\">\n\t\t\t\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-4\/12 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/diagnostics\/?p=2442&post_type=diagnostic_resource&preview=1&_ppp=c9772050c9\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/dx-box-img.png&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Webinar<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">The Realities of Running Next-Generation Sequencing Liquid Biopsy Panels in Clinical Trials<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-4\/12 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"#0\" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/Liquid-Biopsy-iStock-Photo-2-e1619687085988.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Technical Publication<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">Technical Specification and Performance Evaluation<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\n\t\t\t\t\t\t\t\t\t<article class=\"c-resources__grid u-width-4\/12 u-width-half@l u-width-full@m\">\n\t\t\t\t\n\t\t\t\t\t<a href=\"https:\/\/www.almacgroup.com\/news\/trusight-oncology-family-grows-with-liquid-biopsy-and-high-throughput-assay-additions\/ \" target=\"\">\n\t\t\t\t\t\t<div class=\"c-resources c-overlay__ u-a-center lazyload\" style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/12\/Liquid-Biopsy-iStock-Photo-2-e1619687085988.jpg&#039;)\">\n\t\t\t\t\t\t\t<div class=\"c-resources__gradient-inner\">\n\t\t\t\t\t\t\t\t<p class=\"c-resources__type u-text-small u-bold u-m-b1\">Article<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-normal\">TSO-500 ctDNA (RUO) PR<\/h3>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/article>\n\t\t\t\t\t<\/div>\n\t<\/div>\n<\/article> -->\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Almac Diagnostic Services offer a range of comprehensive next-generation sequencing (NGS) Liquid Biopsy solutions, including large and mid-size panels, analysed using the Illumina NovaSeq6000 and NextSeq 500\/550 sequencing platforms. Our Liquid Biopsy solutions offer BioPharma clients a non-invasive approach, providing a rapid and precise translational research &amp; biomarker discovery tool for early diagnosis screening, drug [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"template-page-wrapper.php","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-2274","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Liquid Biopsy Solutions - Diagnostic Services<\/title>\n<meta name=\"description\" content=\"Discover Almac Diagnostic Services range of comprehensive next-generation sequencing (NGS) Liquid Biopsy solutions, including large and mid-size panels\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/diagnostics\/liquid-biopsy-solutions\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Liquid Biopsy Solutions\" \/>\n<meta property=\"og:description\" content=\"Discover Almac Diagnostic Services range of comprehensive next-generation sequencing (NGS) Liquid Biopsy solutions, including large and mid-size panels\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.almacgroup.com\/diagnostics\/liquid-biopsy-solutions\/\" \/>\n<meta property=\"og:site_name\" content=\"Diagnostic Services\" \/>\n<meta property=\"article:modified_time\" content=\"2025-05-20T14:06:19+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2025\/05\/90109_Liquid_Biopsy_Diagram_01_DESKTOP_FINAL_AW.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1750\" \/>\n\t<meta property=\"og:image:height\" content=\"875\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.almacgroup.com\/diagnostics\/liquid-biopsy-solutions\/\",\"url\":\"https:\/\/www.almacgroup.com\/diagnostics\/liquid-biopsy-solutions\/\",\"name\":\"Liquid Biopsy Solutions - 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