{"id":62,"date":"2020-01-22T10:23:57","date_gmt":"2020-01-22T10:23:57","guid":{"rendered":"https:\/\/www.almacgroup.com\/diagnostics\/?page_id=62"},"modified":"2023-05-18T12:18:45","modified_gmt":"2023-05-18T11:18:45","slug":"angio","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/angio\/","title":{"rendered":"Angio"},"content":{"rendered":"\n<h5 class=\"wp-block-heading\" id=\"h-almac-s-predictive-assay-for-anti-angiogenic-agents\">Almac\u2019s Predictive Assay for Anti-Angiogenic Agents<\/h5>\n\n\n\n<p>Almac has identified and validated a powerful gene expression biomarker which identifies a molecular subgroup of patients who may benefit from anti-angiogenic therapy following standard of care chemotherapy.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>This assay has the potential to be used as a companion diagnostic for anti-angiogenic agents across a range of disease areas.<\/p>\n<\/blockquote>\n\n\n\n<div style=\"height:24px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p>Almac initially presented the identification of this molecular subgroup at ASCO 2011 and&nbsp;further validation of&nbsp;the signature in the ICON7 clinical trial was presented by&nbsp;Dr. Charlie Gourley from the University of Edinburgh at ASCO 2014: &#8216;<a href=\"http:\/\/ascopubs.org\/doi\/abs\/10.1200\/jco.2014.32.15_suppl.5502\">Molecular subgroup of high-grade serous ovarian cancer (HGSOC) as a predictor of outcome following bevacizumab<\/a>&#8216;.<\/p>\n\n\n\n<p>Additional validation studies are currently being performed in&nbsp;high-grade serous ovarian cancer (HGSOC) as well as in other cancer types.<\/p>\n\n\n\n\n    <div class=\"u-flex u-flex-justify-start   u-m-t-auto \">\n                            <a class=\"c-btn c-btn-secondary c-btn--red\" href=\"\/diagnostics\/contact-us\/\">Contact Us<\/a>\n                    <\/div>\n\n\n\n<div style=\"height:48px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<div class=\"u-flex u-block@m\">\n<div class=\"u-align-center u-p-a2 u-bg-light-grey u-m-r1 u-m-b1\" style=\"max-width: 400px;\">\n<p><a href=\"\/diagnostics\/claratreport\/\"><img decoding=\"async\" class=\"aligncenter wp-image-51373 lazyload\" data-src=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/claraT-logo.png\" alt=\"\" width=\"154\" height=\"108\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 154px; --smush-placeholder-aspect-ratio: 154\/108;\"><noscript><img decoding=\"async\" class=\"aligncenter wp-image-51373 \" src=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/claraT-logo.png\" alt=\"\" width=\"154\" height=\"108\"><\/noscript><\/a><\/p>\n<h4><a href=\"\/diagnostics\/claratreport\/\">Almac Angio Assay<\/a><\/h4>\n<\/div>\n<div class=\"u-align-center u-p-a2 u-bg-light-grey u-m-r1 u-m-b1\" style=\"max-width: 400px;\">\n<p><br>\n<img decoding=\"async\" class=\"aligncenter wp-image-51374 lazyload\" data-src=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Untitled-3.png\" alt=\"\" width=\"394\" height=\"166\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 394px; --smush-placeholder-aspect-ratio: 394\/166;\"><noscript><img decoding=\"async\" class=\"aligncenter wp-image-51374\" src=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Untitled-3.png \n\" alt=\"\" width=\"394\" height=\"166\"><\/noscript><\/p>\n<\/div>\n<\/div>\n<div class=\"u-align-center u-p-a2 u-bg-light-grey u-m-r1 u-m-b1\" style=\"max-width: 665px;\">\n<p>Assessment of the Almac AADx Assay can be made through use of Almac Diagnostic Services unique gene expression report, <a href=\"\/diagnostics\/claratreport\/\">clara<sup>T<\/sup><\/a>.This provides visualisation of the AADx Assay scores as an easy-to-interpret graduated bar.<\/p>\n<\/div>\n\n\n\n<div style=\"height:48px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"o-wrapper\">\n\t<div class=\"o-grid\">\n\n\t\t<div class=\"o-grid__item u-width-full \">\n\t\t\t\t\t\t\t<h2 class=\"u-m-b4\">Related resources<\/h2>\n\t\t\t\t\t<\/div>\n\n\t<\/div>\n            <div class=\"o-grid u-flex-align-stretch u-m-b3\">\n\n            \n                                            <article class=\"o-grid__item u-width-6\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x4 u-p-y3 u-m-b2\">\n                \n                        \n                                                    <p class=\"c-resource__category\">Poster<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Poster  Predictive assay for anti-angiogenic agents identifies a molecular subgroup of RAS wt mCRC with low efficacy of FOLFIRI plus bevacizumab<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-secondary c-btn--red\" href=\"\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/03\/Predictive-assay-for-anti-angiogenic-agents-AADx-identifies-a-molecular-subgroup-of-RAS-wt-mCRC-with.pdf\" target=\"\">Learn more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-6\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x4 u-p-y3 u-m-b2\">\n                \n                        \n                                                    <p class=\"c-resource__category\">News<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">Almac validates novel test for Ovarian Cancer patients<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-secondary c-btn--red\" href=\"\/news\/almac-validates-novel-test-for-ovarian-cancer-patients\" target=\"\">Learn more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                    <\/div>\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Almac\u2019s Predictive Assay for Anti-Angiogenic Agents Almac has identified and validated a powerful gene expression biomarker which identifies a molecular subgroup of patients who may benefit from anti-angiogenic therapy following standard of care chemotherapy. This assay has the potential to be used as a companion diagnostic for anti-angiogenic agents across a range of disease areas. [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":51,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-62","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Angio - Diagnostic Services | Almac\u2019s Predictive Assay for Anti-Angiogenic Agents<\/title>\n<meta name=\"description\" content=\"A powerful gene expression biomarker which identifies a molecular subgroup of patients who may benefit from anti-angiogenic therapy following standard of care chemotherapy.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/angio\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Angio\" \/>\n<meta property=\"og:description\" content=\"A powerful gene expression biomarker which identifies a molecular subgroup of patients who may benefit from anti-angiogenic therapy following standard of care chemotherapy.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/angio\/\" \/>\n<meta property=\"og:site_name\" content=\"Diagnostic Services\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-18T11:18:45+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/11\/Almac_Logo-e1698941154737.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"100\" \/>\n\t<meta property=\"og:image:height\" content=\"52\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/angio\/\",\"url\":\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/angio\/\",\"name\":\"Angio - 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