{"id":70,"date":"2020-01-22T10:27:04","date_gmt":"2020-01-22T10:27:04","guid":{"rendered":"https:\/\/www.almacgroup.com\/diagnostics\/?page_id=70"},"modified":"2023-05-18T12:18:56","modified_gmt":"2023-05-18T11:18:56","slug":"coldx","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/coldx\/","title":{"rendered":"ColDx"},"content":{"rendered":"\n<h5 class=\"wp-block-heading\" id=\"h-almac-s-breakthrough-biomarker-for-stage-ii-iii-colon-cancer\">Almac\u2019s Breakthrough Biomarker for Stage II\/III Colon Cancer<\/h5>\n\n\n\n<p>This true example of a powerful multiplex signature involves a 634\u2013probe set signature that can identify patients at high-risk for recurrence and\/or high risk for cancer-related death. Importantly, it has been shown to perform independently from known prognostic factors.<\/p>\n\n\n\n<p>The work has been validated in two independent studies, both of which have been published in The Journal of Clinical Oncology. (For further information, you can find links to these papers below). Both studies show the ColDx assay to be a significant, independent predictor of recurrence-free interval in stage II colon cancer therefore indicating it\u2019s potential utility with traditional clinical risk markers to refine patient prognosis.<\/p>\n\n\n\n<p>Professor Richard Kennedy, MD, PhD, McClay Professor in Medical Oncology, Queens University Belfast and VP and Medical Director, Almac Diagnostic Services commented,&nbsp;\u201cThe ability to accurately stratify stage II colon cancer patients into low and high risk categories provides invaluable information, ensuring clinicians are better informed when deciding the most appropriate treatment for their patients\u201d.<\/p>\n\n\n\n<blockquote class=\"wp-block-quote is-layout-flow wp-block-quote-is-layout-flow\">\n<p>This&nbsp;assay has now been launched in the US by&nbsp;Helomics Therapeutics Inc.\u00ae&nbsp;as GeneFX colon, and will help identify those patients at greatest risk of cancer recurrence, for whom chemotherapy may be a useful option following surgery.<\/p>\n<\/blockquote>\n\n\n\n<div style=\"height:20px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n\n    <div class=\"u-flex u-flex-justify-start   u-m-t-auto \">\n                            <a class=\"c-btn c-btn-secondary c-btn--red\" href=\"\/diagnostics\/contact-us\/\">Contact Us<\/a>\n                    <\/div>\n\n\n\n<div style=\"height:56px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<div class=\"o-wrapper\">\n\t<div class=\"o-grid\">\n\n\t\t<div class=\"o-grid__item u-width-full \">\n\t\t\t\t\t\t\t<h2 class=\"u-m-b4\">Related Resources<\/h2>\n\t\t\t\t\t<\/div>\n\n\t<\/div>\n            <div class=\"o-grid u-flex-align-stretch u-m-b3\">\n\n            \n                                            <article class=\"o-grid__item u-width-4\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                        \n                                                    <p class=\"c-resource__category\">Podcast<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">ColDx helps guide stage II colon cancer treatment- Hosted by Cancer Network<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-secondary c-btn--red\" href=\"https:\/\/www.cancernetwork.com\/view\/could-gene-assay-help-guide-stage-ii-colon-cancer-treatment\" target=\"\">Learn more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-4\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                        \n                                                    <p class=\"c-resource__category\">Publication<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">View ColDX second Clinical Validation in the Journal of Clinical Oncology<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-secondary c-btn--red\" href=\"https:\/\/ascopubs.org\/doi\/full\/10.1200\/JCO.2015.65.4699\" target=\"\">Learn more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                                            <article class=\"o-grid__item u-width-4\/12 u-width-4\/12@l u-width-6\/12@m u-width-full@s u-flex u-m-b3 u-a-full\">\n                    <div class=\"c-related-resources__panel u-flex u-flex-direction-column u-flex-align-flex-start u-p-x2 u-p-y2 u-m-b2\">\n                \n                        \n                                                    <p class=\"c-resource__category\">Publication<\/p>\n                        \n                                                    <h4 class=\"u-m-t2\">View ColDX first Clinical Validation in the Journal of Clinical Oncology<\/h4>\n                        \n                        \n                                                                                                                        <a class=\"u-m-t-auto c-btn c-btn-secondary c-btn--red\" href=\"https:\/\/ascopubs.org\/doi\/full\/10.1200\/JCO.2011.35.4498\" target=\"\">Learn more<\/a>\n                                                                                                        <\/div> <!-- \/c-related-resoucres__panel -->\n                    <\/article>\n                    <\/div>\n    <\/div>\n","protected":false},"excerpt":{"rendered":"<p>Almac\u2019s Breakthrough Biomarker for Stage II\/III Colon Cancer This true example of a powerful multiplex signature involves a 634\u2013probe set signature that can identify patients at high-risk for recurrence and\/or high risk for cancer-related death. Importantly, it has been shown to perform independently from known prognostic factors. The work has been validated in two independent [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":51,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-70","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>ColDx - Diagnostic Services<\/title>\n<meta name=\"description\" content=\"Almac\u2019s Breakthrough Biomarker for Stage II\/III Colon Cancer\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/coldx\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ColDx\" \/>\n<meta property=\"og:description\" content=\"Almac\u2019s Breakthrough Biomarker for Stage II\/III Colon Cancer\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/coldx\/\" \/>\n<meta property=\"og:site_name\" content=\"Diagnostic Services\" \/>\n<meta property=\"article:modified_time\" content=\"2023-05-18T11:18:56+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.almacgroup.com\/diagnostics\/wp-content\/uploads\/sites\/3\/2020\/11\/Almac_Logo-e1698941154737.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"100\" \/>\n\t<meta property=\"og:image:height\" content=\"52\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/coldx\/\",\"url\":\"https:\/\/www.almacgroup.com\/diagnostics\/portfolio-overview\/coldx\/\",\"name\":\"ColDx - 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