{"id":970,"date":"2020-10-02T08:48:12","date_gmt":"2020-10-02T07:48:12","guid":{"rendered":"https:\/\/www.almacgroup.com\/discovery\/?page_id=970"},"modified":"2020-10-27T15:57:18","modified_gmt":"2020-10-27T15:57:18","slug":"breath-border-and-regions-airways-training-hub-post-doctorate-researcher-research-fellow","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/discovery\/breath-border-and-regions-airways-training-hub-post-doctorate-researcher-research-fellow\/","title":{"rendered":"\u2018BREATH\u2019 (Border and Regions Airways Training Hub)  Post-Doctorate Researcher \/ Research Fellow"},"content":{"rendered":"\n<p>A Post-Doctoral Research Fellowship has been funded under the European Union\u2019s INTERREG VA Programme for a pioneering cross-border research project, designed to better understand and alleviate the impact of Chronic Obstructive Airways Disease (COPD).<\/p>\n\n\n\n<p>The BREATH project involves a strong cross-border partnership between the Smooth Muscle Research Centre (Dundalk Institute of Technology; DkIT), the School of Pharmacy and Wellcome-Wolfson Institute of Experimental Medicine&nbsp;(Queen\u2019s University Belfast; QUB) and the Institute of Biomedical &amp; Environmental Health Research (University of the West of Scotland; UWS) and Almac Discovery. It has established a world-class cluster of researchers, involving collaborations between scientists and clinicians that will help to address the causes, treatment and potential prevention of COPD.<\/p>\n\n\n\n<div style=\"height:32px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n<!-- Accordions -->\n<section class=\"u-bg-light-grey u-p-y4 t-theme-component-overwrite\" id=\"accordionBlock\">\n\t<div class=\"o-wrapper\">\n\t\t<div class=\"o-grid o-grid--center\">\n\t\t\t<div class=\"o-grid__item u-width-full u-align-center u-align-left@m\">\n\t\t\t\t\t\t\t\t\t<h2 class=\"u-line-height-140 u-a-center@s u-c-mid-grey\"><p>Applications are invited for the following position:<\/p>\n<\/h2>\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t<div class=\"u-m-t2\">\n\t\t\t\t\t<div class=\"c-accordion js-accordion\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item1\" class=\"c-accordion__item u-c-mid-grey accordion-1\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">Post-Doctorate Researcher \/ Research Fellow (Almac Discovery)<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>The Post-Doctorate Researcher \/ Research Fellow will be required to initiate, develop and manage high level research projects in line with the objectives of the BREATH project, which is funded by the EU&#8217;s INTERREG VA Programme, managed by the SEUPB.<\/p>\n<p>This position will involve working as an active member of the cross-border research consortium, with a specific focus on targeting deubiquitinases (DUBs) to develop new treatments for airways disease, including chronic obstructive pulmonary disease (COPD). The successful applicant will be based in Almac Discovery\u2019s state of the art laboratories on the Life Sciences Campus at Queen\u2019s University, Belfast.<\/p>\n<p>Almac Discovery is a research driven drug discovery company with operations at Queen\u2019s University Belfast (medicinal chemistry and biology) Edinburgh (protein therapeutics) and Manchester (bio-informatics). The combination of the highest quality science, dedicated, passionate people and access to a strong academic network allow Almac Discovery to succeed in the challenging world of modern drug discovery. We work creatively and energetically to translate early stage research from concept to therapeutic opportunity.<\/p>\n<p>The role holder will be involved in target identification and validation of DUBs in airways diseases, including running CRISPR-based screens in disease relevant cellular systems, as well as using novel DUB inhibitors to interrogate new biological pathways of importance in airways disease.<\/p>\n<p>Applicants must possess a PhD in biology, biochemistry, molecular \/ cellular biology or another relevant life science discipline. In addition, they will possess an excellent scientific background and expertise, experimental knowledge and hands-on experience in target identification and\/or validation and molecular \/ cellular biology. The ideal applicant will have a track record of publication in high quality peer reviewed journals, commensurate with their stage of career.<\/p>\n<p>It would be highly desirable for the successful post holder to possess previous experience in an area relevant to airways disease and in ubiquitin drug discovery. Previous experience of CRISPR gene-editing technology and familiarity with assay design and set-up of in vitro assays relevant to drug discovery would also be advantageous.<\/p>\n<p>Further enquiries regarding this position may be directed to Xavier Jacq, Vice President Biology, Almac Discovery (<a href=\"mailto:xavier.jacq@almacgroup.com\">xavier.jacq@almacgroup.com<\/a>)<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<svg class=\"c-accordion__arrow u-m-t1 u-m-l3\" width=\"8px\" height=\"18px\" viewBox=\"0 0 8 18\" version=\"1.1\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\">\n\t\t\t\t\t\t\t\t    <defs>\n\t\t\t\t\t\t\t\t        <path d=\"M5,0 L5,11 L8,11 L4,18 L0,11 L3,11 L3,0 L5,0 Z\" id=\"path-1\"><\/path>\n\t\t\t\t\t\t\t\t    <\/defs>\n\t\t\t\t\t\t\t\t    <g id=\"Almac-Components\" stroke=\"none\" stroke-width=\"1\" fill=\"none\" fill-rule=\"evenodd\">\n\t\t\t\t\t\t\t\t        <g id=\"Artboard\" transform=\"translate(-39.000000, -34.000000)\">\n\t\t\t\t\t\t\t\t            <g id=\"icons\/path-arrow\" transform=\"translate(39.000000, 34.000000)\">\n\t\t\t\t\t\t\t\t                <g id=\"Group-3\">\n\t\t\t\t\t\t\t\t                    <mask id=\"mask-2\" fill=\"white\">\n\t\t\t\t\t\t\t\t                        <use xlink:href=\"#path-1\"><\/use>\n\t\t\t\t\t\t\t\t                    <\/mask>\n\t\t\t\t\t\t\t\t                    <use id=\"Combined-Shape\" fill=\"#207392\" fill-rule=\"nonzero\" xlink:href=\"#path-1\"><\/use>\n\t\t\t\t\t\t\t\t                    <rect id=\"Rectangle\" fill=\"#4C565C\" mask=\"url(#mask-2)\" x=\"0\" y=\"0\" width=\"8\" height=\"20\"><\/rect>\n\t\t\t\t\t\t\t\t                <\/g>\n\t\t\t\t\t\t\t\t            <\/g>\n\t\t\t\t\t\t\t\t        <\/g>\n\t\t\t\t\t\t\t\t    <\/g>\n\t\t\t\t\t\t\t\t<\/svg>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article id=\"item2\" class=\"c-accordion__item u-c-mid-grey accordion-2\">\n\t\t\t\t\t\t        <h4 class=\"c-accordion__title u-bg-white u-c-mid-grey js-accordionTarget-one\">How to apply<\/h4>\n\t\t\t\t\t\t        <div class=\"c-accordion__content u-bg-white\">\n\t\t\t\t\t\t\t\t\t<div class=\"o-grid\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if image is there then allow content to sit with it -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- if not then content goes full width -->\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<p>Applications for all positions should be in the form of a CV with names of two referees and should be sent to recruit@almacgroup.com, quoting reference PDR2020.<\/p>\n<p>Applicants should also include a cover letter detailing their suitability for the relevant position. They should also include an official copy of degree(s) (if applicable, an official English translation) and any English proficiency test result required, which must be sent as PDFs in a single email.<\/p>\n<p>This post is initially offered on a 12 month fixed term basis commencing in January 2020 with a\u00a0 possibility of extension.<\/p>\n<p>No other form of application will be accepted.<\/p>\n<p><strong>The closing date for receipt of applications is Thursday 29th October 2020 at 1700 hours.<\/strong><\/p>\n<p><strong>Late applications are not accepted.<\/strong><\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/article>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<\/div> <!-- \/c-tabs -->\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div> <!-- \/o-grid -->\n\t<\/div> <!-- \/o-wrapper -->\n<\/section>\n\n\n\n<div style=\"height:63px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 class=\"has-vivid-cyan-blue-color has-text-color has-text-align-center wp-block-heading\">This project has been supported by the EU\u2019s INTERREG VA Programme, managed by the Special EU Programmes Body (SEUPB)<\/h3>\n\n\n\n<div class=\"wp-block-image\"><figure class=\"aligncenter size-large\"><img decoding=\"async\" width=\"500\" height=\"122\" data-src=\"https:\/\/www.almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/09\/Discovery-Interreg.png\" alt=\"\" class=\"wp-image-995 lazyload\" data-srcset=\"https:\/\/www.almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/09\/Discovery-Interreg.png 500w, https:\/\/www.almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/09\/Discovery-Interreg-300x73.png 300w\" data-sizes=\"(max-width: 500px) 100vw, 500px\" src=\"data:image\/gif;base64,R0lGODlhAQABAAAAACH5BAEKAAEALAAAAAABAAEAAAICTAEAOw==\" style=\"--smush-placeholder-width: 500px; --smush-placeholder-aspect-ratio: 500\/122;\" \/><noscript><img decoding=\"async\" width=\"500\" height=\"122\" src=\"https:\/\/www.almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/09\/Discovery-Interreg.png\" alt=\"\" class=\"wp-image-995\" srcset=\"https:\/\/www.almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/09\/Discovery-Interreg.png 500w, https:\/\/www.almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/09\/Discovery-Interreg-300x73.png 300w\" sizes=\"(max-width: 500px) 100vw, 500px\" \/><\/noscript><\/figure><\/div>\n\n\n<!-- TX1 title-image.php -->\n\t\t\t<div class=\"c-box-link-title-image below bottom black strip-blue standard \">\n\t\t\t<div class=\"o-wrapper\">\n\t\t\t\t<div class=\"o-grid u-flex-align-stretch\">\n\t\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t\t<h2 class=\"u-p-b4 u-a-center\"><\/h2>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"o-grid u-flex-align-stretch u-m-b6@m u-overflow-hidden u-overflow-initial@l \">\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"o-grid__item u-width-6\/12 u-width-full@s\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- Show the correct button based off pop up to show or not -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/09\/Post-Doc-Researcher-Job-Description-September-2020.pdf\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<header class=\"c-link-box__image lazyload\" \n                                                                        role=\"img\" aria-label=\"\" \n                                                                        style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/04\/Job-Description.jpg&#039;)\">\n   \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/header>\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"c-link-box__content strip-blue\">\n\t\t\t\t\t\t\t\t\t\t<div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-m-b2\">Job description <\/h3>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-m-b2\">\n\t\t\t\t\t\t\t\t\t\t\t\tAccess the full job description here.\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\n\n    <div class=\"  u-m-t-auto \">\n                            <div class=\"c-btn c-btn-secondary c-btn--red\">Download<\/div>\n                    <\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<!-- Only show pop up if acf is checked to show it -->\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t<\/article>\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<article class=\"o-grid__item u-width-6\/12 u-width-full@s\" id=\"\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<!-- Show the correct button based off pop up to show or not -->\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"https:\/\/almacgroup.com\/wp-content\/uploads\/2019\/10\/Almac-Employee-Benefits-Table-UK-version.pdf\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\n\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<header class=\"c-link-box__image lazyload\" \n                                                                        role=\"img\" aria-label=\"\" \n                                                                        style=\"background-image:inherit;\" data-bg-image=\"url(&#039;https:\/\/www.almacgroup.com\/discovery\/wp-content\/uploads\/sites\/2\/2020\/04\/Fun-Run.jpg&#039;)\">\n   \t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/header>\n\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"c-link-box__content strip-blue\">\n\t\t\t\t\t\t\t\t\t\t<div>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"u-m-b2\">Reward<\/h3>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"u-m-b2\">\n\t\t\t\t\t\t\t\t\t\t\t\tFrom opportunities for career development to a selection of benefit options, we want all who join our team to realise their full potential.\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\n\n    <div class=\"  u-m-t-auto \">\n                            <div class=\"c-btn c-btn-secondary c-btn--red\">Download<\/div>\n                    <\/div>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t<!-- Only show pop up if acf is checked to show it -->\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t<\/article>\n\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\t\n\n\n<div style=\"height:23px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>A Post-Doctoral Research Fellowship has been funded under the European Union\u2019s INTERREG VA Programme for a pioneering cross-border research project, designed to better understand and alleviate the impact of Chronic Obstructive Airways Disease (COPD). The BREATH project involves a strong cross-border partnership between the Smooth Muscle Research Centre (Dundalk Institute of Technology; DkIT), the School [&hellip;]<\/p>\n","protected":false},"author":7,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-970","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>\u2018BREATH\u2019 (Border and Regions Airways Training Hub) Post-Doctorate Researcher \/ Research Fellow - Discovery<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/discovery\/breath-border-and-regions-airways-training-hub-post-doctorate-researcher-research-fellow\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"\u2018BREATH\u2019 (Border and Regions Airways Training Hub) Post-Doctorate Researcher \/ Research Fellow\" \/>\n<meta property=\"og:description\" content=\"A Post-Doctoral Research Fellowship has been funded under the European Union\u2019s INTERREG VA Programme for a pioneering cross-border research project, designed to better understand and alleviate the impact of Chronic Obstructive Airways Disease (COPD). 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