Molecular-logic based computation (MLBC) has grown by accumulating many examples of combinational logic gates and a few sequential variants. In spite of many inspirations being available in biology, there are virtually no examples of MLBC in chemistry where sequential and combinational operations are integrated. Here we report a simple alcohol-ketone redox interconversion which switches a macrocycle between a large or small cavity, with erect aromatic walls which create a deep hydrophobic space or with collapsed walls respectively.
Our VP Technology Development and Commercialization, Tom Moody, recently contributed to this published article in Nature Communications entitled, “Molecular memory with downstream logic processing exemplified by switchable and self-indicating guest capture and release.”