Biocatalysis: Genes to GMP
Biocatalysis is increasingly providing a practical and cost-effective route to complex chiral molecules, intermediates and APIs. In this article, Tom Moody, Head of Biocatalysis & Radiolabelling at Almac Group, explores Almac’s “genes to GMP” approach, showing how enzyme identification, engineering and process optimisation can progress into scalable GMP manufacturing. Through real-world case studies, the article highlights how technologies including enzyme evolution, in silico design and process intensification can improve efficiency, reduce waste and deliver more sustainable chemical processes.
Read the full article to discover how Almac is taking biocatalysis from enzyme design and development through to scalable GMP manufacture.