Peak Purity of Peptides and Large Molecules by Accurate Mass LC-MS
Traditional UV-based peak purity analysis can become less effective as molecules increase in size and complexity, potentially leaving co-eluting impurities undetected. This whitepaper explores how Almac Sciences uses High Resolution Accurate Mass LC-MS to provide greater insight into peak purity for peptides and large molecules. Through peptide and monoclonal antibody case studies, it demonstrates how accurate mass spectrometry can detect, characterise and potentially quantify impurities hidden beneath the principal chromatographic peak.
Read the whitepaper to discover how accurate mass LC-MS can provide deeper insight into peak purity for peptides and large molecules.