Shielding a healing signal: Protecting CXCL12 unlocks its regenerative power
CXCL12 plays an important role in tissue repair, but its therapeutic potential can be limited by rapid degradation in protease-rich environments such as wounds. This Almac Voice explores a novel approach using chlorite-oxidised oxyamylose (COAM) to protect CXCL12 from degradation while preserving its biological activity. The research demonstrates how extending CXCL12 stability can enhance wound healing and highlights the wider potential of this approach for regenerative medicine, tissue repair and other protease-sensitive chemokine therapies.
Read the full Almac Voice to explore how protecting CXCL12 could help unlock its potential in wound healing and regenerative medicine.