Trace Impurity identification using Q-TOF mass spectroscopy
Accurate identification of trace impurities is critical to pharmaceutical development and quality control. This case study explores how Q-TOF accurate mass spectrometry, combined with targeted MS/MS and advanced molecular formula generation, can support the isolation, identification and structural elucidation of trace impurities in APIs and formulated drug products. Through a practical example, the study demonstrates how the approach successfully determined the structure of a trace impurity identified during API stability evaluation.
Read the case study to discover how Q-TOF mass spectrometry can support accurate identification and structural elucidation of trace impurities.