Solubility Enhancement

Improving the Bioavailability of your Compound

Many APIs have poor physicochemical properties that may struggle to get sufficient exposure when dosed to patients. We can develop a variety of formulations that potentially offer improvements in the bioavailability of your compound.

Through our advanced techniques, we can offer:

• Micronisation of API
• Spray dried amorphous material (aqueous & solvent capabilities)
• Solubilised / lipid-based systems

Never limiting ourselves to the technologies we have available in-house, we are happy to accommodate your particular approach or platform technology and will work with external parties.

To tackle the bioavailability challenges of your compound, our knowledgeable scientists will assess different formulations by developing discriminatory dissolution methods and by arranging comparative bioavailability studies. With their expertise, they can also devise a practical way to take one of these approaches forward to GMP manufacture.