{"id":1383,"date":"2025-09-09T11:37:45","date_gmt":"2025-09-09T10:37:45","guid":{"rendered":"https:\/\/www.almacgroup.com\/pharmaceutical-drug-product-development\/?page_id=1383"},"modified":"2025-09-09T11:37:46","modified_gmt":"2025-09-09T10:37:46","slug":"hot-melt-extrusion","status":"publish","type":"page","link":"https:\/\/www.almacgroup.com\/pharmaceutical-drug-product-development\/hot-melt-extrusion\/","title":{"rendered":"Hot Melt Extrusion"},"content":{"rendered":"\n<p>At Almac, our melt extrusion process creates stable amorphous solid dispersions (ASDs)&nbsp; that improve solubility, absorption, and therapeutic performance.<\/p>\n\n\n\n<p>Our scientists use advanced formulation tools, including Design of Experiments (DoE), to optimise polymer selection, process parameters and excipient compatibility. <\/p>\n\n\n\n<p>From pre-formulation to GMP manufacture, trust Almac with to unlock the potential of your drug product.<\/p>\n\n\n\t<div class=\"\">\n\t\t<div class=\"o-wrapper\">\n\t\t\t<div class=\"o-grid\">\n\t\t\t\t<div class=\"o-grid__item u-width-full\">\n\t\t\t\t\t<div class=\"s-cms\">\n\t\t\t\t\t\t<p id=\"hubspotform\"><\/p>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/div>\n\n\t\n","protected":false},"excerpt":{"rendered":"<p>At Almac, our melt extrusion process creates stable amorphous solid dispersions (ASDs)&nbsp; that improve solubility, absorption, and therapeutic performance. Our scientists use advanced formulation tools, including Design of Experiments (DoE), to optimise polymer selection, process parameters and excipient compatibility. From pre-formulation to GMP manufacture, trust Almac with to unlock the potential of your drug product.<\/p>\n","protected":false},"author":1287,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-1383","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v25.3.1 (Yoast SEO v26.3) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Hot Melt Extrusion - Pharmaceutical Development<\/title>\n<meta name=\"description\" content=\"Almac&#039;s melt extrusion process creates stable amorphous solid dispersions that improve solubility, absorption, and therapeutic performance.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.almacgroup.com\/pharmaceutical-drug-product-development\/hot-melt-extrusion\/\" \/>\n<meta property=\"og:locale\" content=\"en_GB\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Hot Melt Extrusion\" \/>\n<meta property=\"og:description\" content=\"Almac&#039;s melt extrusion process creates stable amorphous solid dispersions that improve solubility, absorption, and therapeutic performance.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.almacgroup.com\/pharmaceutical-drug-product-development\/hot-melt-extrusion\/\" \/>\n<meta property=\"og:site_name\" content=\"Pharmaceutical Development\" \/>\n<meta property=\"article:modified_time\" content=\"2025-09-09T10:37:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/www.almacgroup.com\/pharmaceutical-drug-product-development\/wp-content\/uploads\/sites\/5\/2020\/11\/Almac_Logo.jpeg\" \/>\n\t<meta property=\"og:image:width\" content=\"640\" \/>\n\t<meta property=\"og:image:height\" content=\"334\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Estimated reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.almacgroup.com\/pharmaceutical-drug-product-development\/hot-melt-extrusion\/\",\"url\":\"https:\/\/www.almacgroup.com\/pharmaceutical-drug-product-development\/hot-melt-extrusion\/\",\"name\":\"Hot Melt Extrusion - 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