Flow Chemistry for Challenging Development Pathways
Harnessing continuous processing technologies to solve complex synthetic and manufacturing challenges.
Custom & Flow Chemistry
Some chemical transformations present challenges that cannot be efficiently addressed through traditional batch manufacturing. Factors such as reaction safety, scalability, heat transfer, mixing efficiency and process control can all limit the viability of conventional approaches.
At Almac Sciences, we apply custom and continuous flow chemistry technologies to help overcome these challenges. Combining deep process chemistry expertise with advanced reactor technologies, we develop practical, scalable manufacturing routes that improve efficiency, enhance process understanding and reduce development risk.
From early feasibility assessments through to manufacturing implementation, we work closely with customers to identify where flow chemistry can deliver meaningful advantages and support the development of robust processes ready for scale-up and commercialisation.
Almac’s integrated flow technology platform can be applied throughout your product lifecycle to guide your synthesis project from conception to manufacture.
We offer the following:
- Route invention using continuous flow technology.
- Proof of concept studies and process demonstration.
- Packed bed hydrogenations, rapid pelletised catalyst screening and process optimisation, custom built flow rig for rapid scale up.
- Flow as an enabling technology for suitable reactions in multi-step synthetic routes.
- Reaction validity in flow and process robustness within microreactor.
- Process tech transfer and product delivery.
- Lab scale production to low kgs.
- UV-photochemical flow cell and LED’s.
- Development capabilities for both batch and flow and their integration.
- Enzyme immobilisation development and associated flow processes.
- Suspension polymerisation.
- UF/DF.
- Microbubble technology.
Custom and Flow Chemistry Technical Expertise
Published Papers
Dr Scott Wharry
Custom and Flow Chemistry Manager
Scott is the Custom and Flow Chemistry Manager at Almac Sciences. Scott has extensive experience managing multi-disciplinary teams in process development, technology transfer for multi-kg manufacturing and biocatalysis projects. He is responsible for continuous processes at Almac.
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