Articles & Publications
Publication
Discovery and characterization of highly potent and selective allosteric USP7 inhibitors
Nature Chemical Biology volume 14, pages 118–125(2018)
Gerald Gavory, Colin R O’Dowd, Matthew D Helm, Jakub Flasz, Elias Arkoudis, Anthony Dossang, Caroline Hughes, Eamon Cassidy, Keeva McClelland, Ewa Odrzywol, Natalie Page, Oliver Barker, Hugues Miel & Timothy Harrison
Publication
Identification and characterisation of dual inhibitors of the USP25/28 deubiquitinating enzyme subfamily
ACS Chem Biol, 2017, 12, 3113-3125
Jonathan D Wrigley, Gerald Gavory, Iain Simpso, Marian Preston 1 , Helen Plant, Jenna Bradle , Anne U Goeppert, Ewelina Rozycka, Gareth Davies, Jarrod Walsh, Andrea Valentine, Keeva McClelland, Krzysztofa Ewa Odrzywol , Jonathan Renshaw, Joanna Boros, Jonathan Tart, Lindsey Leach, Thorsten Nowak, Richard A Ward, Timothy Harrison, David M Andrews
Publication
Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors
ACS Med. Chem. Lett. 2018, 9, 3, 238–243
Colin R. O’Dowd, Matthew D. Helm, J. S. Shane Rountree, Jakub T. Flasz, Elias Arkoudis, Hugues Miel, Peter R. Hewitt, Linda Jordan, Oliver Barker, Caroline Hughes, Ewelina Rozycka, Eamon Cassidy, Keeva McClelland, Ewa Odrzywol, Natalie Page, Stephanie Feutren-Burton, Scarlett Dvorkin, Gerald Gavory, Timothy Harrison