Protein Characterisation

Our new fully GMP Thermo Scientific Q Exactive BioPharma MS/MS Hybrid Quadrupole-Orbitrap Mass Spectrometer takes full advantage of the high-resolution, accurate-mass (HRAM) capabilities of the Orbitrap mass analyser to enable three key protein characterisation workflows:

  • Denatured and native MS intact analysis
  • Disulfide bridge mapping, subunit and top/middle-down analysis
  • Peptide mapping

Combined with experience in sample preparation, analysis experiments,  UHPLC and data processing technologies, Almac can provide complete solutions for the rigorous structural characterisation of biotherapeutic compounds.

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