Specialty Central Lab Service Tablet Image Specialty Central Lab Service Mobile Image
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Specialty Central Lab Service

Specialty Central Lab Service Tablet Image Specialty Central Lab Service Mobile Image
Mobile Gradient

Specialty Central Lab Service

 

Specialty Central Lab Service

Almac Diagnostic Services offer a premium ‘white glove’ Specialty Central Lab service on a ‘Project by Project’ basis. We can take care of your end-to-end needs acting as your central lab vendor who can also seamlessly integrate with other labs.

We can conduct your specimen lab management & processing, storage, data needs and downstream analysis either in-house or work with other vendors to ship samples to them for analysis.

Our specialty lab solutions include a range of platforms including qPCR & NGS platforms and a range of proteomic and single cell options for molecular analysis.

Benefits of partnering with Almac

Utilising Almac as your specialty central lab service provider provides reassurance your clinical specimens are being stored safely and are readily accessible as required (no long lead times to retrieve or process specimens).

Our premium service can be tailored to client’s individual needs, providing complete flexibility for your biomarker programmes. Offering the service on a project-by-project basis ensures that you are not locked-in to long term punitive contracts and charges in comparison to other service providers in the market.

Services

Specialty Central Lab Service – Additional Information

Sample receipt and accessioning

SAMPLE RECEIPT AND ACCESSIONING -Sample Management Service

Almac receive and accession a range of biological material including:

  • Fresh Frozen Tissue.
  • FFPE tissue.
  • Whole Blood / Bone Marrow Aspirates.
  • Range of Derivatives.

Almac’s dedicated Sample Management Team ensure that there is full sample traceability from the moment the samples are received at our sites, ensuring that there are no breaks in the chain of custody.

Importantly, Almac focus on quality and incorporate a range of QC checks throughout the sample lifecycle. From the initial stages of reception at Almac; assessing package integrity, sample integrity and sample suitability for processing. Protecting clinical specimens is critical, and supports to success of further downstream applications.

Your Almac assigned dedicated Point of Contact (POC), will work closely with you to ensure that all required information is accessioned accurately, and maintain your LIMS inventory information. Your POC will work with you to curate the inventory and support reconciliations in a timely manner.

All samples are given a unique Almac LIMS barcode. This identifier ensures full traceability throughout processing and storage conditions throughout the lifecycle of the sample within Almac.

Sample Preparation and QC

Sample Preparation and QC - Sample Management Service

Almac Diagnostic Services has over 20 years’ experience in preparing samples for molecular analysis from a range of sample types.

Whether it is the preparation of FFPE tissue slides for pathology review or extraction of ctDNA from isolated plasma, Almac ensure this work is performed by a highly experienced team following procedures outlined in our dedicated SOPs.

Almac’s team of Consultant Pathologists are able to remotely conduct digital pathology review on H&E samples, generating high quality, annotated digital images for clients.

Lab inventory management (LIMS) & Reporting

Almac’s LIMS ensures sample information is uploaded to a protected and audited environment.

Throughout the sample processing lifecycle, LIMS ensures full traceability, including storage locations, processing history, shipment/disposal status, thereby ensuring full chain of custody of the sample at all times.

Information generated throughout the sample lifecycle is also automatically uploaded into LIMS: Sample accessioning information, H&E pathology information, nucleic acid QC and processing history.

All of this information links directly to the unique Almac LIMS barcode which is assigned to the sample at the point of receipt.

Bespoke reports can be developed by our Data Management team to retrieve and format data contained in our LIMS system to meet your specified requirements, ensuring full visibility of your sample and overall inventory.

Bespoke client reporting

Bespoke Client Sample Reports

Bespoke reports can be developed by our Data Management team to retrieve and format data contained in our LIMS system to meet your specified requirements, ensuring full visibility of your sample and overall inventory.

Integrations with Client Systems & Third-Party Vendor Systems

Bespoke integrations with Biopharma client or 3rd party data systems can also be implemented to facilitate seamless transfer of sample associated data/metadata as required.

Data Management Team

  • Almac Diagnostic Services Data Management staff have experience in standard formatted data returns (e.g. SDTM/CDISC) and can accommodate a wide range of file formats such as:
    • SAS xpt
    • CSV
    • Excel
    • ASCII delimited

Storage

Almac offer a range of fully validated, HTA compliant, short term and long term storage solutions covering:

  • Ambient storage.
  • Cold storage (+4°C, -20°C)
  • Ultra Low Temperature Storage (-80°C, LN2).
  • We have the storage capacity to suit your study needs, no matter what the size.

All of our storage units are recorded on our LIMS system, providing a full and accurate inventory.

All samples are stored in Almac secure storage units and are temperature monitored 24/7 with a committed response team in the event of any temperature excursions.

Logistics

 

Almac can manage all your logistical requirements in-house at one location, from the courier collection of the sample at the clinical site to confirmation of delivery at the end destination. This ensures Almac has full visibility on the shipment, ensuring time and temperature sensitive material reaches its destination safely. Almac’s experience allows us to predict, prevent and overcome logistical obstacles, ensuring rapid transit of your valuable clinical samples.

Downstream molecular analysis

Our DNA and RNA sequencing services are supported by our state-of-the-art laboratory technologies which are ideally suited to biomarker discovery, development and delivery for clinical trials.

We also have a team of highly qualified and experienced scientists, bioinformaticians, and biostatisticians with substantial knowledge and experience in state of the art genomic technologies and their use in a highly regulated clinical testing environment.

We recognise that each study is unique and has its own challenges. Our team will work with collaborators and clients throughout the project to provide a comprehensive tailored service – from initial study design and planning, all the way through to the interpretation of results, and will integrate seamlessly as part of your extended team.

We offer complete transparency throughout every study, with all methodology, programs and analytical methods clearly explained and available for review. We pride ourselves on quality and we work under strict standard operating procedures (SOPs). All analytical methods we use are extensively tested and verified generating the highest quality data for downstream analysis.

Almac’s end to end Sample Management Service includes integrated services including Specimen Collection & Logistics, Specimen and Data Management, Sample Processing, Storage & Downstream Molecular Analysis.

Our dedicated project management teams will provide end to end oversight to ensure your needs are met on time and within budget.

Almac Sample Management Service

Find out more on each element of Almac’s Sample Management service by following the links below. We also offer an integrated Clinical Trial Specimen Collection & Logistics Service.

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