Peptide Vaccine Cocktails


Peptide Vaccine Cocktails

The use of multiple peptide antigens in a single drug product is becoming an increasingly popular approach for the development of vaccines.

This approach offers the advantage of using short peptides that are relatively straightforward to manufacture, whilst maximising the likelihood of generating the required immune response for a successful vaccine. Each peptide drug substance is manufactured separately and released for combination into a single drug product.

Almac has experience in supporting several peptide vaccine cocktail projects. As well as performing process development and GMP manufacture of each peptide drug substance, our analytical expertise comes to the fore in devising analytical methods which are appropriate not just for the individual peptides, but also for the drug product mix. Additionally we support development of an understanding of the peptides’ physical chemistry properties, which can be crucial in developing an appropriate method of generating the peptide cocktail.

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