Advancing Flow Chemistry Scale-Up Through Integrated Chemical Engineering

Scaling up flow processes in the fine chemical and pharmaceutical industries is underpinned by the integration of chemical engineering and process chemistry. Continuous processing is vital for achieving efficiency, productivity, and sustainability within chemical manufacture and is aligned with good corporate social responsibility.

At Almac Sciences (Almac), the implementation of scalable flow processes has augmented the way chemical processes are performed, ensuring that the transition from laboratory to industrial scale is seamless and effective across their sites in Ireland.

This article, published in the July / August 2025 edition of Chemistry Today, explores the strategic implementation of flow chemistry, highlighting its role in innovation, cost reduction, and environmental impact mitigation, with case studies in high-pressure hydrogenation and low-temperature formylation.