Home / Knowledge Centre /
Patent

Squalene Hopene Cyclase derivatives and use thereof for producing Ambrox

A squalene hopene cyclase enzyme was first discovered and later engineered to catalyse the cyclization of Homofarnesol to Ambrox, which is widely used as a fixative by the fragrance and perfume industry. For a reaction scale of 50g/L of substrate and 2.5% of enzyme loading the best variants show up to 142-fold improvement in activity over the WT enzyme.

Read patent WO2022051761A2 and WO2023245039A1 to find out more.

View Resource

Download here instantly

This website uses cookies. By continuing to browse the site, you are agreeing to our use of cookies