Squalene Hopene Cyclase variants for producing Sclareolide

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Squalene Hopene Cyclase variants for producing Sclareolide

Variants of squalene hopene cyclase (SHC) are provided for enzymatically converting homofamesoic acid to sclareolide, which can be non-enzymatically converted to ambrox.

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Modular Synthesis of Benzoylpyridines Exploiting a Reductive Arylation Strategy

Origin of the enantioselectivity of alcohol dehydrogenase