The identification and use of robust transaminases from a domestic drain metagenome
Transaminases (TAms) remain one of the most promising biocatalysts for use in chiral amine synthesis, however their industrial implementation has been hampered by their general substrate acceptance.
Almac recently published a manuscript (Moody, T.S. et al. Green Chemistry (2018). “The identification and use of robust transaminases from a domestic drain metagenome”). which described the identification, cloning and screening of 29 novel transaminases from a UK household drain metagenome.
Almac API, Chemical Development, Analytical & Solid State Services
Almac Sciences provides integrated services from development to commercial scale of advanced intermediates and Active Pharmaceutical Ingredients (API).
We provide a range of services for small molecules (including highly potent) and peptides. We have a proven track record of saving time and cost through the integration of our services and application of innovative biocatalysis and technology solutions.
We offer a full suite of analytical testing for a range of different product types including small molecules, peptides, biologics, conjugates, potent and controlled substances.
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