Home / Knowledge Center /
Technical Publication

The identification and use of robust transaminases from a domestic drain metagenome

Transaminases (TAms) remain one of the most promising biocatalysts for use in chiral amine synthesis, however their industrial implementation has been hampered by their general substrate acceptance.
Almac recently published a manuscript (Moody, T.S. et al. Green Chemistry (2018). “The identification and use of robust transaminases from a domestic drain metagenome”). which described the identification, cloning and screening of 29 novel transaminases from a UK household drain metagenome.

View Resource
Almac Logo

Almac API, Chemical Development, Analytical & Solid State Services

Almac Sciences provides integrated services from development to commercial scale of advanced intermediates and Active Pharmaceutical Ingredients (API).

We provide a range of services for small molecules (including highly potent) and peptides. We have a proven track record of saving time and cost through the integration of our services and application of innovative biocatalysis and technology solutions.

Learn More

We offer a full suite of analytical testing for a range of different product types including small molecules, peptides, biologics, conjugates, potent and controlled substances.

Our vast pool of scientific knowledge can help to overcome the analytical challenges that typically arise during drug development.

Learn More

Download here instantly

This website uses cookies. By continuing to browse the site, you are agreeing to our use of cookies