Radiolabeling: Manufacture of 14C-Labelled Drug Product
The approach taken for a client who trusted Almac for the manufacture and supply of 14C-labelled antibody drug conjugate for their drug development program.
A large pharmaceutical organization approached Almac for the supply of a 14C-labelled drug product (IMP) to be provided as a powder in capsule formation. The 14C-API was required at a final specific activity of 1µCi/mg and as a particular polymorph (Form B) with a particle size of <5µm.
Almac API, Chemical Development, Analytical & Solid State Services
Almac Sciences provides integrated services from development to commercial scale of advanced intermediates and Active Pharmaceutical Ingredients (API).
We provide a range of services for small molecules (including highly potent) and peptides. We have a proven track record of saving time and cost through the integration of our services and application of innovative biocatalysis and technology solutions.
We offer a full suite of analytical testing for a range of different product types including small molecules, peptides, biologics, conjugates, potent and controlled substances.
Our vast pool of scientific knowledge can help to overcome the analytical challenges that typically arise during drug development.