Like many other companies and institutions around the world, we are experiencing interference with some of our systems within the TNT network.
We are implementing remediation steps as quickly as possible. We have implemented operational contingencies to continue to complete collections from customers with scheduled stops. For customers who do not have a regular stop, collection should be arranged via our customer service centers.
Customers may experience delays in the transit of shipments, particularly inter-continental or non-EU European delivery, as we work to remediate our systems. Additionally, if customers do not have the facility for self-labeling, they may also experience delays.
We are not able to collect shipments of dangerous goods at this time.
We regret any inconvenience to our customers.
With our extensive experience in the synthesis and analysis of stable and 14C isotope labelled compounds – from drug discovery through to launch - we can label any compound at any stage, including small molecules, peptides and larger bio molecules.
Our custom radiolabelling service encompasses QC and analytical support, including method development and validation, method transfer and radiolabelling stability studies from our state-of-the-art facilities.
We are MHRA certified for 14C IMP manufacture and GMP compliance and we are fully equipped to deliver an industry-leading, cost-effective radiolabelling service.
Isotopic labelling imposes many synthetic challenges beyond those found in normal chemical synthesis. When the isotope is radioactive, this becomes even more demanding. That’s why we offer advice on the most appropriate label position for your molecule, including feasibility and metabolic stability.
Our strong track record in providing a complete suite of custom radiolabelling solutions includes:
- GMP & non-GMP stable & 14C-labelled API synthesis
- Biology & fermentation expertise
- Labelled metabolites
- QC & analytical support
- Solid dosage form (powder in bottle & capsule formulations)
- selectAZymeTM enzymes for selective and mild transformation
- Storage & repurification
- Stability studies & storage advice
Our highly skilled team are enabled to offer custom radiolabelling services within a dedicated controlled access GMP facility using validated quality-critical equipment including:
- Tri-Carb 2900 and 4900 scintillation analysers
- 3, 5, and 6 point analytical balances
- Multiple Agilent HPLCs with radioflow, UV and fluorescence detection
- Stromboli KF equipment
- 2-8°C, -20°C and -80°C fridges and freezers
- Malvern Mastersizer 3000
- X-ray powder diffraction (XRPD)
- Topcount 12 channel scintillation analyser