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Insights into Flow and Continuous Systems in Pharmaceutical Manufacturing: Challenges and Opportunities
Article

Insights into Flow and Continuous Systems in Pharmaceutical Manufacturing: Challenges and Opportunities

Expert name: Megan Smyth

Megan Smyth

Angles of Insight: Exploring the Geometry of XRPD
Article

Angles of Insight: Exploring the Geometry of XRPD

A Solution To Overcome The Solution Stability Challenges Associated With Determination Of Residual Phosphine Ligands In Active Pharmaceutical Ingredients (API) And Their Intermediates
Article

A Solution To Overcome The Solution Stability Challenges Associated With Determination Of Residual Phosphine Ligands In Active Pharmaceutical Ingredients (API) And Their Intermediates

API Industry Review Roundtable: API Manufacturing – Key Trends Reshaping the Global Market
Article

API Industry Review Roundtable: API Manufacturing – Key Trends Reshaping the Global Market

Expert name: Tom Moody

Tom Moody

Case study

Optimizing API and Drug Product Development Through an Integrated CMC Strategy

Almac Voice

Environmental Monitoring in Pharmaceutical Manufacturing: Safeguarding Quality with Almac’s Expertise

Article

Almac’s Integrated Nitrosamine Impurity Solutions

Article

Ritter reactions in continuous flow catalyzed by a solid-supported sulfonic acid catalyst

Article

The Impact of Continuous Flow Technology and Collaboration between Academia and Industry

Webinar

Bioavailability Enhancement: Integrated Solutions from Early Development to GMP Manufacture

Blog

From Lab to Patient: The Importance of Stability Studies

Almac Voice

Mind Minders – Chemokines role in the inflammation associated with Schizophrenia

Almac Voice

Fusion Enzymes: Innovating Biocatalysis

Blog

Analytical Method Development for Pediatric Oral Dose Products

Case study

Precision in Biologic Development: Leveraging Orthogonal Techniques for Superior Insights

Case study

Determination of Peptide Chiral Purity Using Marfey’s Reagent and Accurate Mass Liquid Chromatography Mass Spectrometry

Blog

Bioavailability Enhancement: A Seamless Path to Clinical Success

Brochure

Continuous Flow Manufacturing Capabilities

Brochure

Speciality Chemical Development and Manufacture

Technical Sheet

A Sustainable-by-Design Process for the Selective Photooxidation of Ethylbenzene in a Scalable Agitated Baffle Reactor

Case study

Ensuring excellence in over-encapsulation manufacture amid supply chain challenges

Brochure

Bioavailability Enhancement Solutions Brochure

Case study

Sotax AT MD Semi Automated Dissolution System

Whitepaper

Use of SDS-PAGE for Residual Protein Determination

Article

Advancing Flow Chemistry Scale-Up Through Integrated Chemical Engineering

Almac Voice

Orthogonal Techniques in Biologic Development: Advancing Precision with Almac’s Expertise

Technical Publication

Synthesis of Psilocin, Psilocybin and 5-MeO-DMT Succinate, All Labeled With Carbon-14at the Indole 2-Position

Poster

Ensuring Pharmaceutical Safety: Mass Spectrometry Approaches to Nitrosamine Analysis

Podcast

Leaders in Pharma Podcast Featuring Jonathan Loughrey and Terry Ernest

Brochure

Think Almac. Targeted Theranostics

Case study

Overcoming common challenges to determine residual impurities using IC in APIs with limited water

Podcast

How Almac’s Trust Ownership Enables CDMO Success

Case study

Analytical method optimzation with Fusion QbD Software – Illustrative Case Study by Almac Sciences

Case study

Analytical method optimzation with Fusion QbD software –illustrative case studies for a synthetic peptide and small molecule Active Pharmaceutical Ingredient(API) by Almac Sciences

Article

Continuous Flow Synthesis of β-Aminoketones as Masked Vinyl Ketone Equivalents

Article

Unlocking Drug Longevity: The Crucial Role of Stability Studies

Article

Structurally Diverse Nitrogen-Rich Scaffolds via Continuous Photo-Click Reactions

Technical Publication

BioStructNet: Structure-Based Network with Transfer Learning for Predicting Biocatalyst Functions

Article

Bioalkylation Strategies to Synthesize Allylated Tetrahydroisoquinolines by Using Norcoclaurine Synthase and O-Methyltransferases

Almac Voice

The development of cutaneous limits for elemental impurities

Case study

Validation of a GC-FID headspace method for quantitative detection of silicone oils (siloxane polymers) within the lyophilisation life cycle

Whitepaper

Peak Purity of Peptides and Large Molecules by Accurate Mass LC-MS

Case study

Accurate determination of resin substitution in solid phase peptide synthesis

Almac Voice

Evaluation of the effects of residual carbon content matrix on the determination of pharmaceutically regulated elemental impurities by ICP-MS

Case study

Impurity level confirmation by Nuclear Magnetic Resonance (NMR) Spectroscopy

Article

Unlocking Bio/Pharma Potential: The Strategic Advantages of Outsourcing to CMOs and CDMO

Almac Voice

Navigating the complex world of radiopharmaceutical development with Almac

Whitepaper

Almac Sciences’ INSIGHT Platform Accelerates Genes-to-GMP Implementation

Article

Chemoselective oxidative N-debenzylation of aryl halogenated amines using the Laccase LAC97/TEMPO system

Article

Continuous Flow Approach for Benzylic Photo-oxidations Using Compressed Air

Article

Development and Scale-Up of 7‑COOH CBD Synthesis, a Key Cannabinoid Metabolite

Article

Preparative Chromatography of Peptides and Other Large Molecules

Article

Oxidation of Alcohols and Aldehydes with Peracetic Acid and a Mn(II)/Pyridin-2-Carboxylato Catalyst: Substrate and Continuous Flow Studies

Technical Publication

Modular Synthesis of Benzoylpyridines Exploiting a Reductive Arylation Strategy

Technical Publication

Origin of the enantioselectivity of alcohol dehydrogenase

Technical Publication

Application of rational enzyme engineering in a new route to Etonogestrel and Levonorgestrel: Carbonyl reductase bioreduction of ethyl secodione

Technical Publication

A pharma perspective on sustainability advantages through adoption of continuous flow

Technical Publication

Enzyme Screening and Engineering for N- and O‑Demethylation:Key Steps in the Synthesis of Buprenorphine

Technical Publication

Squalene Hopene Cyclase variants for producing Sclareolide

Technical Publication

Origin of the enantioselectivity of alcohol dehydrogenase

Article

The future of C-14 environmental tracing

Patent

Cleaning composition comprising an engineered fatty acid alpha-dioxygenase

Patent

Squalene Hopene Cyclase derivatives and use thereof for producing Ambrox

Almac Voice

Rejecting Rejection: The CCL18-CCR8 pathway may be key to stopping transplantation rejection symptoms.

Whitepaper

Generic method approach for determination of residual solvents in active pharmaceutical ingredients by gas chromatography

Brochure

Think Almac…¹⁴C Radiolabeling

Case study

Quantitative NMR of challenging materials

Technical Publication

Cleaning composition comprising an engineered fatty acid alpha-dioxygenase

Case study

Analytical method development for synthetic peptide for purity and impurities content by UHPLC

Almac Voice

Radiochemical stability of carbon-14 compounds

Almac Voice

Peptide UHPLC development

Technical Publication

A proposal that would ban manufacture, supply, and use of all Fluoropolymers and most Fluorinated Reagents within the entire EU

Article

Continuous-flow transfer hydrogenation ofbenzonitrile using formate as a safe and sustainable source of hydrogen

Article

Continuous Flow Synthesis of Cyclobutenes using LED technology

Case study

N- and C-terminal sequence analysis

Poster

An approach for the characterization of biologic products by Accurate Mass Orbitrap LC MS

Technical Publication

Nitrilase mediated mild hydrolysis of a carbon-14 nitrile for the radiosynthesis of [14C]-SHP-141

Technical Publication

Enzyme Optimization and Process Development for a Scalable Synthesis of (R)‑2-Methoxymandelic Acid

Technical Publication

Convergent Biocatalytic Mediated Synthesis of siRNA

Article

Discovery and Rational Mutagenesis of Methionine Sulfoxide Reductase Biocatalysts To Expand the Substrate Scope of the Kinetic Resolution of Chiral Sulfoxides

Almac Voice

Almac’s Radiolabeling services: enhancing drug development efficiency and regulatory compliance

Almac Voice

Profiller 1100/1120 Hand-Held Capsule Filling System for Use in Selection and Laboratory Development of Over-Encapsulated Products

Technical Publication

Continuous Flow Epoxidation of Alkenes Using a Homogeneous Manganese Catalyst with Peracetic Acid

Technical Publication

Rational engineering of a carboxylesterase for the synthesis of polyesters for biomedical applications

Brochure

Think Almac…Continuous Flow Technology

Almac Voice

Peptide mapping – navigating the way through structural characterization

Brochure

Crystallization Process Development

Almac Voice

Preformulation Development

Almac Voice

Silencing the CCL2 Chemokine

Article

Leveraging Prior Knowledge to Demonstrate Analytical Competency

Almac Voice

Registered Starting Material Testing

Technical Publication

Development of Enzymatic Variants for the Synthesis of Bioresorbable Polyesters

Technical Publication

Development of a Personalized Tumor Neoantigen Based Vaccine Formulation (FRAME-001) for Use in a Phase II Trial for the Treatment of Advanced Non-Small Cell Lung Cancer

Almac Voice

A digital approach to building better peptides

Article

Transitioning your therapeutic peptide program from research to clinic

Video

Dr Megan Smyth – Future Leaders program

Almac Voice

Chemokines signal the future in the treatment of SARS-CoV-2 infection

Almac Voice

The Road to GMP

Technical Publication

Stereoselective Transaminase-Mediated Synthesis of Serotonin and Melatonin Receptor Agonists

Poster

Modern Methods in Peptide Conjugation

Poster

Peptides for Cancer Research

Poster

Solid Phase Peptide Synthesis of Full-Length Modified Histones

Poster

5 Dimensional Structural Characterization of Synthetic Peptides

Poster

Carbon-14 Labeled Peptides

Brochure

Biocataltic Oligonucleotide Synthesis Technology

Article

Psilocybin: Characterization of the Metastable Zone Width (MSZW), Control of Anhydrous Polymorphs, and Particle Size Distribution (PSD)

Article

The Safe Hands of ICP-MS

Article

Improved peptide analytical technologies and the impact on process development

Article

Transitioning your therapeutic peptide program from research to clinic

Article

Efficient, low-energy chemical synthesis using enzymes for biocatalysis

Article

Nuclear Magnetic Resonance: The new gold standard release test of the future?

Technical Publication

Continuous flow photooxidation of alkyl benzenes using fine bubbles for mass transfer enhancement

Almac Voice

The Power of Spectroscopy in the investigation of unknown impurities

Almac Voice

Biologics…changing treatment, saving lives

Q&A

2nd Applied Biocatalysis Summit: Interview with Jill Caswell

Almac Voice

QNMR – a modern alternative to HPLC

Whitepaper

Have you got the physical form of your API under control?

Poster

Integrated CMC: Early Tox to Phase I

Article

Outsourcing analytical services…because it’s worth it

Article

Coupling Biocatalysis with High-Energy Flow Reactions for the Synthesis of Carbamates and β-Amino Acid Derivatives

Article

Interrupted Curtius Rearrangements of Quaternary Proline Derivatives: A Flow Route to Acyclic Ketones and Unsaturated Pyrrolidines

Article

Evaluating the Green Credentials of Flow Chemistry towards Industrial Applications

Almac Voice

Quality Control Release Testing – more than a tick box exercise

Poster

HPLC method development for analysis of a multi-component drug product

Poster

Trace Impurity Identification using Q-TOF Mass Spectroscopy

Article

Exploring ICP-MS expertise at Almac

Poster

Impurity Identification by Peptide Sequencing using 2D-LC MS/MS

Q&A

Molecule to Market Podcast: The stickability factor with Prof. Tom Moody

Publication

Discovery of new carbonyl reductases using functional metagenomics and applications in biocatalysis

Publication

Recent trends in enzyme immobilization – concepts for expanding the Biocatalysis toolbox

Article

The impact of the European Pharmacopeia Regulations for peptides during the change of manufacturer at late phase

Case study

Spotlight on stability: API and drug product testing

Article

Spotlight on stability: API and drug product testing

Poster

Chemical synthesis of chemokines: accessing novel research reagents

Article

Towards the enzymatic synthesis of oligonucleotides | Manufacturing Chemist

Article

Manufacturing Chemist Interview: Alistair Hay Head of Peptide Business and Process Development

Article

Flow chemistry surges forward

Technical Publication

Compatibility of Insulin Lispro, Aspart, and Glulisine with the Solo™ MicroPump, a Novel Miniature Insulin Pump

Publication

Coupling biocatalysis with high-energy flow reactions for the synthesis of carbamates and β-amino acid derivatives

Brochure

cGMP Peptide Manufacture

Article

Biocatalysis – How secret should it be?

Technical Publication

A Facile Stereoselective Biocatalytic Route to the Precursor of Woody Acetate

Technical Publication

Characterization of a solvent-tolerant haloarchaeal (R)-selective transaminase isolated from a Triassic period salt mine

Whitepaper

Ensuring Consistency in Polymorphic Drug Substances and Products

Whitepaper

Modern Perspectives on Peptide Synthesis

Technical Publication

Streamlined Preparation of Immobilized Candida antarctica Lipase B

Article

Antibody-Drug Conjugates: Carbon-14 Labeling Requirements

Webinar

Limit Test: Ensuring Consistency in Polymorphic Drug Substances & Products

Poster

Limit tests by XRPD

Article

Enzyme Processes, Past Present and Future

Whitepaper

Early phase drug development: Assessing, predicting and formulating with delivery in mind

Technical Publication

Dynamic kinetic resolution of 2-methyl-2-nitrocyclohexanol: Combining the intramolecular nitroaldol (Henry) reaction & lipasecatalysed resolution

Technical Sheet

Positron Emission Tomography Neuro-Imaging

Technical Publication

Characterization of a novel w-transaminase from a Triassic salt mine metagenome

Article

Technology-driven isotopic labeling in API development

Article

Carbon-14 Bioconjugation: Peptides and Antibody Drug Conjugates

Poster

Analytical Services: Overcoming challenges in particle size measurement by laser diffraction technique

Article

Antibody-Drug Conjugates (ADCs) – Biotherapeutic bullets

Article

Radiolabeling: Seeing Through The Mist

Technical Publication

Biocatalysis: A Three-Enzyme System Involving an Ene-Reductase for Generating Valuable Chiral Building Blocks

Article

Radiolabeling: Keeping tags on biomolecules

Technical Publication

Biocatalysis: Overcoming Equilibrium Issues with Carbonyl Reductase Enzymes

Article

Biocatalysis: Accelerating Chemical Development and Minimizing Cost for Fine Chemical / API Manufacture and Metabolite Synthesis

Article

Solid State Services: Why are Solid Forms Still Causing Headaches?

Article

Biocatalysis: Greener, sustainable processes using efficient biocatalyst purification tools at Almac Sciences

Technical Sheet

Radiolabeling: Clinical Applications of Positron Emission Tomography (PET) Imaging in Medicine: Oncology, Brain Diseases and Cardiology

Almac Voice

Radiolabeling: Synthesis of 14C-Labelled Peptide

Case study

Radiolabeling: Manufacture of ¹⁴C-Labelled Drug Product

Case study

Radiolabeling: Manufacture of 14C-Labelled Antibody Drug Conjugate

Case study

Radiolabeling: Requirement for Synthesis of Non-GMP 14C API

Case study

Biocatalysis and Quality in Drug Substance Manufacture

Case study

Mass Spectrometry: Determination of Isotopic Purity by Accurate Mass LC/MS

Case study

Key Strategies Central to Overcoming Poor API Solubility

Case study

Smarter, Faster Cheaper: How API Manufacturers Stay Ahead of The Game

Presentation

Biocatalysis Development: Shortening the Path – Pharmaceutical Materials from Enzymatic Reactions

Presentation

Rational Design of Enzymes to fit the Process Chemist Timelines

Presentation

Peptide Manufacture: Unique Challenges in Process Development

Poster

Mass Spectrometry: An HPLC-MS/MS Assay Method for the Determination of Digoxin in Human Plasma and Urine

Poster

Biocatalysis Development: From P450 to Scale-Up for Delivery of Chiral Intermediates

Poster

Biocatalysis Development: Ered Assay Development and Naphthol Synthesis

Presentation

Carbon -14 Labeled Antibody Drug Conjugates & Peptides

Presentation

Development and Scale-up of a Photochemical Route to a Steroidal API

Poster

Synthetic applications using selectAZyme technology

Presentation

HPLC method development for analysis of a multi component drug product

Technical Sheet

Challenges in the Synthesis of Modified Histones

Presentation

Development of an Efficient and Practical Route for the Multi-kilogram Manufacture of Cyanopyridone AZ10527409 and Chloropyridine AZ10146848

Presentation

Synthetic Strategies for 14C Labeling of Drug Molecules

Presentation

Carbon-14 Labeled Peptide APIs

Whitepaper

Crystallization of Pharmaceutical Compounds – the chemist’s role in protecting intellectual property

Article

Outsourcing peptide production for first in human studies

Article

Enzymes from the salt of the Earth

Article

Radiolabeling is Still Hot

Poster

Development and Scale-Up of an Antibody Drug Conjugate Tubulysin Payload

Technical Publication

Rational Design of a (S)-Selective-Transaminase for Asymmetric Synthesis of (1S)-1-(1,1′-biphenyl-2-yl)ethanamine

Technical Sheet

Making Hot ADCs

Technical Publication

Ene Reductase Enzymes for the Aromatisation of Tetralones and Cyclohexenones to Naphthols and Phenols

Technical Publication

Fluorescent PET (Photoinduced Electron Transfer) sensors as potent analytical tools

Technical Publication

Efficient Magnetic Recycling of Covalently Attached Enzymes on Carbon-Coated Metallic Nanomagnets

Technical Publication

A rapid, sensitive colorimetric assay for the high-throughput screening of transaminases in liquid or solid-phase

Technical Publication

Biocatalytic dearomatisation of para-fluorobenzoic acid

Technical Publication

Isolation and Characterization of a Halotolerant w-Transaminase from a Triassic Period Salt Mine and Its Application to Biocatalysis

Technical Publication

Engineering and application of P450 monooxygenases in pharmaceutical and metabolite synthesis

Technical Publication

Biocatalytic Approaches to the Henry (Nitroaldol) Reaction

Technical Publication

A metagenomics approach for new biocatalyst discovery: application to transaminases and the synthesis of allylic amines

Technical Publication

19th International Isotope Society (UK Group) Symposium: Synthesis & Applications of Labeled Compounds 2010

Article

Natural enzymes – key to 21st century process design

Technical Publication

Development of an Acid-Washable Tag for the Separation of Enantiomers from Bioresolutions

Technical Publication

Benzoate dioxygenase from Ralstonia eutropha B9 – unusual regiochemistry of dihydroxylation permits rapid access to novel chirons

Technical Publication

Hydrolase-mediated resolution of the hemiacetal in 2-chromanols The impact of remote substitution

Almac Voice

Influence of the position of the substituent on the efficiency of lipase-mediated resolutions of 3-aryl alkanoic acids

Technical Publication

A novel lipase enzyme panel exhibiting superior activity and selectivity over lipase B from Candida antarctica for the kinetic resolution of secondary alcohols

Almac Voice

Lipase catalyzed kinetic resolutions of 3-aryl alkanoic acids

Technical Publication

A practical chemo-enzymatic approach to highly enantio-enriched cyanohydrin acetates

Technical Publication

Efficient kinetic bioresolution of 2-nitrocyclohexanol

Technical Publication

Highly stereoselective biocatalytic reduction of alpha-halo ketones

Technical Publication

Simple one-pot process for the bioresolution of tertiary amino ester protic ionic liquids using subtilisin

Article

Biotransformations in chemical synthesis

Article

Biocatalysis is a Key Technology for Successful Chiral Synthesis at Almac

Technical Publication

Practical Methods for Biocatalysis and Biotransformations 2

Technical Sheet

Catalytic mechanism of phenylacetone monooxygenases for non-native linear substrates

Technical Publication

Case Studies Illustrating a Science and Risk-Based Approach to Ensuring Drug Quality When Using Enzymes in the Manufacture of Active Pharmaceuticals Ingredients for Oral Dosage Form

Technical Sheet

Luminescent sensors and photonic switches

Technical Publication

Application of ω‑Transaminases in the Pharmaceutical Industry

Article

Modern Developments in Isotopic Labeling

Article

Biocatalysis: Genes to GMP

Technical Publication

Application of Radionuclides and Antibody-Drug Conjugates to Target Cancer

Technical Publication

Synthesis of isotopically labeled [14C]ZT-1, [d3]ZT-1 & (-)-[d3]huperzine A, a new generation of acetylcholinesterase inhibitors

Technical Publication

Radionuclide Antibody-Conjugates, a Targeted Therapy Towards Cancer

Brochure

Think Almac…selectAZymeᵀᴹ

Brochure

Think Almac…Integrated Enzyme Technologies

Brochure

Comprehensive Chemokine Services Brochure

Brochure

Solid State Services: Solid form screening

Brochure

Almac Sciences Brochure

Brochure

Superior Peptide and Protein Solutions

Brochure

NeoPeptides

Brochure

Analytical Services Brochure

Webinar

Identification and Structural Elucidation by Amino Acid Sequencing of Peptide Impurities by 2DlC-MS/MS

Poster

Identification and Structural Elucidation by Amino Acid Sequencing of Peptide Impurities by 2D-LC MS/MS

Technical Publication

The identification and use of robust transaminases from a domestic drain metagenome

Whitepaper

Isotopic API labeling with carbon-14

Technical Sheet

Spatial requirement for PAMO for transformation of non-native linear substrate

Almac Voice

Melamine Contamination Testing

Article

Ticking a new box in enzyme chemistry

Technical Publication

Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution

Technical Publication

Molecular memory with downstream logic processing exemplified by switchable and self-indicating guest capture and release

Technical Publication

Mechanism of Phosphatidylglycerol Activation Catalyzed by Prolipoprotein Diacylglyceryl Transferase

Technical Publication

Reaction Mechanism of Histone Demethylation in αKG-dependent Non-Heme Iron Enzymes

Article

Managing and redesigning chemical processes with enzymes

Article

Changing the shape of GMP peptide manufacture

Technical Publication

An Industrial Perspective of Ene Reductase (ERED) Biocatalysis

Technical Publication

Synthesis of carbon‐14–labeled peptides

Technical Publication

Biocatalysis in seawater: Investigating a halotolerant ?-transaminase capable of converting furfural in a seawater reaction medium

Technical Publication

Building pH Sensors into Paper-Based Small-Molecular Logic Systems for Very Simple Detection of Edges of Objects

Technical Publication

Preparative access to medicinal chemistry related chiral alcohols using carbonyl reductase technology

Technical Publication

Structural effects on the pH-dependent fluorescence of naphthalenic derivatives and consequences for sensing/switching

Technical Publication

Combining luminescence, coordination and electron transfer for signaling purposes

Technical Publication

Metagenomic ene-reductases for the bioreduction of sterically challenging enones

Technical Publication

Sequential Palladium-Catalyzed Allylic Alkylation/retro-Dieckmann Fragmentation Strategy for the Synthesis of α‑Substituted Acrylonitriles

Technical Publication

A Perspective on Continuous Flow Chemistry in the Pharmaceutical Industry

Almac Voice

Conducting Nitrosamine impurity testing and analysis on drug substance and drug product

Technical Publication

FAST Hydrogenations as a Continuous Platform for Green Aromatic Nitroreductions

Technical Publication

Transaminases for industrial biocatalysis: novel enzyme discovery

Whitepaper

NMR under GxP in Drug Development Manufacturing

Article

Achieving Excellence: An Interview with Tom Moody, VP of Technology Development and Commercialization at Almac.

Whitepaper

Fluorescent Molecular Logic Gates based on Photoinduced Electron Transfer (PET) Driven by a Combination of Atomic and Biomolecular Inputs

Webinar

The Application of NMR for Drug Development and Manufacturing in a Good Manufacturing Practice Setting

Almac Voice

Inventing new GMP peptide manufacture

Technical Publication

Unconventional Biocatalytic Approaches to the Synthesis of Chiral Sulfoxides

Technical Sheet

Overcoming the hurdles and challenges associated with developing continuous industrial processes

Technical Publication

Tandem Continuous Flow Curtius Rearrangement and Subsequent Enzyme-Mediated Impurity Tagging

Almac Voice

Analytical Testing for Clinical Trials – why is it so important?

Webinar

Enzyme identification and engineering for novel industrial enzymes with Twist Biosciences

Presentation

EuroTides 2020 Showcase – Manufacture of complex peptides in a modern world

Article

Analytical Support for Biologics: A conversation with Almac Sciences

Brochure

Analytical Solutions for Biologics

Article

Successful implementation of continuous flow processes

Presentation

Keynote: Novel industrial biocatalysts from engineering/evolution

Presentation

Design of a Competitive Biocatalytic Manufacturing Process – Applied Biocatalysis Summit 2020

Article

Regio- and stereoselectivity in the CYP450BM3-catalyzed hydroxylation of complex terpenoids: a QM/MM study

Article

A mild and chemoselective CALB biocatalysed synthesis of sulfoxides exploiting the dual role of AcOEt as solvent and reagent†

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